Isolation, identification, and optimization of conditions for the degradation of four sulfonamide antibiotics and their metabolic pathways in DLY-21.

Overuse of sulfonamides in aquaculture and agriculture leads to residual drugs that cause serious pollution of the environment. However, the residues of sulfonamides in the environment are not unique, and the existing microbial degradation technology has a relatively low degradation rate of sulfonamides. Therefore, in this study, a strain (DLY-21) with the ability to degrade four common SAs was screened and isolated from aerobic compost.

Study on the Effect of AO-Coupled Constructed Wetlands on Conventional and Trace Organic Pollutant Treatment.

In this study, a pilot-scale integrated process was developed, which combined the integrated biological contact oxidation technology (AO) and the improved constructed wetland technology. The results showed significant removal efficiency for both conventional and trace organic pollutants. The average removal efficiencies for COD, NH-N, and TP were 78.

BAD inactivation exacerbates rheumatoid arthritis pathology by promoting survival of sublining macrophages.

The resistance of synovial sublining macrophages to apoptosis has a crucial role in joint inflammation and destruction in rheumatoid arthritis (RA). However, the underlying mechanism is incompletely understood. Here we report that inactivation of the pro-apoptotic BCL-2 family protein BAD is essential for survival of synovial sublining macrophage in RA.