Publications by authors named "Weichun Cao"

Article Synopsis
  • The study analyzes tumor genomes from over 10,000 cancer patients in China using advanced DNA sequencing technology to identify actionable genomic alterations.
  • It compares genetic changes and tumor characteristics between Chinese and American patient populations, highlighting both similarities and differences.
  • The research reveals that 64% of Chinese patients have clinically actionable genomic alterations, which could influence treatment decisions for targeted therapy and immunotherapy, aiding in personalized medicine approaches.
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Background: Long noncoding RNAs (lncRNAs) have been highlighted as crucial elements in cancer biology. LncRNA activated by transforming growth factor-β (ATB) was identified to promote the development of multiple cancers and may serve as a potential therapeutic target in human cancers. However, to the best of our knowledge, the functional role of ATB in cervical cancer has not been verified yet.

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