Elucidating the chemical interaction effects of herb pair Danshen-Chuanxiong and its anti-ischemic stroke activities evaluation.

Ethnopharmacological Relevance: Salvia miltiorrhiza Bunge (Danshen) and Ligusticum chuanxiong Hort. (Chuanxiong) is the core herb pair in traditional Chinese medicines (TCMs) formulae for treating ischemic stroke. However, the synergistic effect of Danshen-Chuanxiong against anti-ischemic stroke and its compatibility mechanism remains unclear.

Uncovering genomic regions controlling plant architectural traits in hexaploid wheat using different GWAS models.

Wheat is a major food crop worldwide. The plant architecture is a complex trait mostly influenced by plant height, tiller number, and leaf morphology. Plant height plays a crucial role in lodging and thus affects yield and grain quality.

Infectious bronchitis virus inhibits activation of the TLR7 pathway, but not the TLR3 pathway.

Various strains of infectious bronchitis virus (IBV) cause different forms of infectious bronchitis with different clinical signs. Here, primary chicken embryo kidney (CEK) cells and specific-pathogen-free (SPF) chickens were infected with three pathogenic IBV strains, and it was observed that the TLR7-MYD88 pathway was inhibited but the TLR3-TIRF pathway was activated. After treatment with poly(I:C)-LMW, poly (I:C)-LMW/LyoVec, and Imiquimod, the replication of IBV was significantly suppressed after 24 h.

[Endemic features and space - time clustering of schistosomiasis in Xinjian District, Nanchang City from 2009 to 2014].

Objective: To understand the endemic situation and distribution features of schistosomiasis in Xinjian District, Nanchang City, Jiangxi Province from 2009 to 2014, so as to provide a reference for the prevention and control of schistosomiasis in the future.

Methods: The endemic data of schistosomiasis in Xinjian District were collected by taking the village as a unit from 2009 to 2014. An endemic database was established, and the SaTScan software was applied to analyze the spatiotemporal aggregation areas of infection in crowd, snails and cattle.

[Current status of human Schistosoma japonicum infection and reinfection in marshland and lake regions of Xinjian County, Jiangxi Province, China].

Objective: To understand the dynamics of human infection and reinfection of Schistosoma japonicum after chemotherapy in marshland and lake endemic regions so as to provide the evidence for developing a cost-effective control strategy.

Methods: From 2007 to 2011, the schistosome infection, intensities and reinfection of population were investigated and the results were analyzed dynamically in Caohui Village, a national schistosomiasis surveillance site in Changyi Township, Xinjian County, Jiangxi Province, China.

Results: The schistosome infection rate was 3.

[Advanced schistosomiasis chemotherapy and assistance in Xinjian County, 2005-2009].

Objective: To understand the status of chemotherapy and assistance for advanced schistosomiasis patients in Xinjian County, 2005-2009.

Methods: The data of chemotherapy and assistance for patients with advanced schistosomiasis in Xinjian County from 2005 to 2009 were collected and analyzed statistically by using The Information Management System for Advanced Schistosomiasis Chemotherapy and Assistance in Jiangxi Province.

Results: Among 636 cases, the sex ratio of male to female was 1.

[Surveillance of schistosomiasis in Caohui Village, Xinjian County, 2005 - 2010].

The surveillance of schistosomiasis in a national schistosomiasis surveillance site, Caohui Village, Xinjian County, 2005-2010 showed that the infection rates of residents and livestock decreased to below 3% and 5%, respectively. However, the endemic situation was still of instability. Therefore, we should strengthen the comprehensive control measures including the control of infectious sources in the light of local conditions to control the schistosomiasis endemic situation.

[Study on an intervention model of "schools without infected students with schistosoma japonica" in heavy endemic areas].

Objective: To study an intervention model of "schools without infected students with schistosoma japonica", to control and prevent students from schistosoma infection.

Methods: Twelve primary schools of four heavy endemic counties (districts) with schistosomiasis in the Poyang Lake areas were selected as the study fields, of which, ten schools were the experimental groups, and the other two schools were the control groups by cluster random sampling. All enrolment students were the target population.

[Establishment and application of school-based health promotion and intervention model of schistosomiasis in lake-type endemic area].

Objective: To establish an intervention model of school health promotion, and apply it in developing "schistosomiasis-free schools".

Methods: At the pilot stage, all students of Henghu primary school and Banshan primary school in Xinjian County of Jiangxi Province were selected as experiment group and control group, respectively. A baseline survey covered knowledge and attitude on schistosomiasis control, water contact behaviors and Schistosoma japonicum infection rate.