Publications by authors named "Weibo Cheng"

Quality control and grading of Korla fragrant pears significantly impact their commercial value. Rapid and non-destructive detection of soluble solids content (SSC) and firmness is crucial to improving this. This study proposes a method combining near-infrared spectroscopy (NIRS) with machine learning for the rapid, non-destructive detection of SSC and firmness in Korla pears.

View Article and Find Full Text PDF

A route for nitrification and C-H activation/cyclization of ()--allyl-'-benzylidenebenzenesulfonohydrazide and cobalt nitrate via an iron(II)-catalyzed cascade reaction to synthesize nitrated dihydropyrazoles has been developed. The method features convenient operation and good functional group tolerance. In addition, it employs insensitive and inexpensive FeSO as the catalyst and provides a direct approach for the preparation of dihydropyrazoles.

View Article and Find Full Text PDF

Background: Breast cancer is a prevalent malignancy globally, necessitating accurate diagnostic tools for early detection and intervention. Ultrasound imaging plays an important role in breast lesion assessment, with various morphological features serving as key indicators of malignancy.

Objective: This study aimed to employ logistic regression analysis to investigate ultrasound indices for effectively distinguishing between benign and malignant breast masses.

View Article and Find Full Text PDF
Article Synopsis
  • Silicosis is a serious health problem caused by inhaling tiny silica dust, which makes the lungs hurt and can cause permanent damage.
  • Researchers studied how a specific change in RNA (called m6A methylation) is affected when mice are exposed to silica at two different times (7 days and 28 days).
  • The study found that a particular molecule (demethylase FTO) that helps control m6A levels was lower in cells from the lungs of the mice, suggesting it could be important for diagnosing and treating silicosis in people.
View Article and Find Full Text PDF

We report experimental results on the formation of microvoids in bulk sapphire produced through the single-shot illumination of the sample by near-infrared, simultaneously spatially and temporally focused (SSTF) laser beams. Compared with the cases of tightly focused femtosecond Gaussian and flattop beams, the SSTFs produce internal microvoids with significantly larger volumes and without cracks between the interaction sites, which may be beneficial for applications in volumetric data storage and for the studies of exotic, super-dense elemental phases contained in the densified shells surrounding the microvoids.

View Article and Find Full Text PDF

We investigate damage inside the bulk of borosilicate glass by a single shot of IR picosecond laser pulse both experimentally and numerically. In our experiments, bulk damage of borosilicate glass with aspect ratio of about 1:10 is generated. The shape and size of the damage site are shown to correspond to an electron cloud with density of about 1020 cm-3.

View Article and Find Full Text PDF

We introduce a technique to measure fluence distributions in femtosecond laser beams with peak intensity of up to several hundred terawatts per square centimeter. Our approach is based on the dependence of single-shot laser ablation threshold for gold on the angle of incidence of the laser beam on the gold sample. We apply this technique to the profiling of fluence distributions in femtosecond laser filaments at a wavelength of 800 nm in air.

View Article and Find Full Text PDF

The functional significance of the proteasome activator REGγ in the regulation of cell proliferation and apoptosis has been recognized. However, pathological contributions to tumor development remain to be elucidated. Both oncogenic proteins and tumor suppressors are targeted by REGγ for proteasomal degradation.

View Article and Find Full Text PDF

We report for the first time (to our knowledge) a diode-pumped Nd:YAG laser emitting at 869 nm based on the (4)F(3/2)-(4)I(9/2) transition, generally used for a 946 nm emission. Power of 453 mW at 869 nm has been achieved in cw operation with a fiber-coupled laser diode emitting 35.4 W at 809 nm.

View Article and Find Full Text PDF

From April 2009 onward, a new strain of human H1N1 influenza virus has swept over the world. The genome of influenza virus consists of 8 segments, encoding 10 proteins, respectively. The reassortments among the 8 segments cause the variation of influenza virus.

View Article and Find Full Text PDF

We report for the first time (to our knowledge) cw orange-yellow emission at 589 nm from a compact double-end diffusion-bonded Nd(3+):LuVO(4) self-Raman laser with intracavity frequency doubling in LiB(3)O(5), pumped by an 880 nm diode laser. A 3.5 W cw orange-yellow emission with an overall diode-to-visible conversion efficiency of 13.

View Article and Find Full Text PDF

We generated efficient blue laser output at 454 nm by intracavity frequency doubling of a continuous-wave (cw) diode-pumped Nd:YLiF(4) (Nd:YLF) laser at 908 nm based on the (4)F(3/2)-(4)I(9/2) transition. With 32.8 W of incident pump power at 880 nm and the frequency-doubling crystal LiB(3)O(5), a level as high as 4.

View Article and Find Full Text PDF

Objective: To explore the mechanism and the compensation proceeding of thyroid hyperplasia caused by PTU.

Methods: PTU was administered to rats by gavage at a dose of 5.0 mg/kg B.

View Article and Find Full Text PDF

Objective: To observe the effects of Panax notoginseng saponins (PNS) on anti-hyperglycemic, anti-obese and prevention from kidney pathological changes in a type 2 diabetic KK-Ay gene mice model.

Methods: All animals were divided into 4 groups: Normal control group (C57BL/6J mice) were treated by NS 10 mL/kg, KK-Ay mice were subdivided into 3 groups as DM administrated NS 10 mL/kg, PNS 50 mg/kg, PNS 200 mg/kg respectively. All the animals received daily intraperitoneal injections for 30 days consecutively.

View Article and Find Full Text PDF

Objective: To observe the efficacy of hydrogel dressings in preventing and treating vein injury of rabbits so as to provide a experimental evidence for clinical application.

Methods: Twenty-four healthy large-eared Japanese rabbits (48 ears) were chosen, weighing (2.15 +/- 0.

View Article and Find Full Text PDF

Objective: Establish an effective method for in vivo short-time standardized discriminating system of thyroid hormone disruptors.

Methods: 4 experimental groups treated with PTU lavage for 3, 6, 9, 12 days respectively and one dissolvent group for control. 10 rats in each group were sacrificed in due time with the serum being extracted and detected for T3, T4 and TSH by chemoluminescence.

View Article and Find Full Text PDF

To investigate the evidence of electrified death without electric mark, four animal models were developed, which were electrified to death without electric mark left, contrasted with four non-electrified to death models. Erythrocyte and endothelium of aorta and pulmonary artery were observed by scanning electron microscope. It was suggested that some pores can only be seen on the surface of erythrocytes and endothelial cells of aorta and pulmonary artery of those death models group two electrified.

View Article and Find Full Text PDF

Objective: To study the changes of HSP 70 mRNA and c-fos mRNA expression and to find a method to differentiate antemortem from postmortem electrocution.

Methods: Fifteen New Zealand rabbits were randomly divided into three groups, the antemortem electrocution group, the postmortem electrocution group, and the control group. Each group consists of five rabbits.

View Article and Find Full Text PDF
Article Synopsis
  • This study aimed to examine the levels of adiponectin in the placenta and its relationship with preeclampsia in pregnant women.
  • Researchers collected placental samples from three groups: normal pregnancies, mild preeclampsia, and severe preeclampsia, and used immunohistochemistry and RT-PCR to measure adiponectin protein and mRNA levels.
  • Results showed that adiponectin protein levels were significantly lower in the severe preeclampsia group compared to both normal and mild preeclampsia groups, suggesting a potential link between reduced adiponectin expression and the severity of preeclampsia.
View Article and Find Full Text PDF

Objective: To study the preventing effects of procyanidins (PC) on selenite cataract in rats and the time-effect relationship.

Method: Forty five SD rats were divided into three groups: control, model and experiment groups. The rats in the experiment group were fed additionally with the PC by 80 mg x kg(-1) when they were supplied the equal selenite with the model group.

View Article and Find Full Text PDF

Some electrocution deaths occur without detectable current marks on the skin, making forensic examination to determine the true cause of death more difficult. Because arterial thrombosis was a frequent finding in victims of electrocution, we investigated injury to the endothelium of the aorta and pulmonary artery with a scanning electron microscope in five cases of death known to be caused by electrocution. We found large pores on the surface of endothelial cells of the aorta and pulmonary artery in those who died of electrocution, but no endothelial membrane perforation was found in those who died of cardiac diseases.

View Article and Find Full Text PDF

Objective: To study the expression rule of proliferating cell nuclear antigen (PCNA) in thyroid when the hyperplasia of male rat thyroid is induced by propylthiouracil (PTU).

Methods: PTU was administered to rats by gavage at a dose of 5.0 mg/kg B.

View Article and Find Full Text PDF

Objective: To study the effect of pesticide N'N-methylene-bis on thyroid function in rats, and the time-effect relationship.

Methods: N'N-methylene-bis dimethylsulfoxide solution was administered to rats by gavage at a dose of 50 mg/kg body weight for 1, 3, and 5 days respectively. The rats in the control group were given solvent dimethylsulfoxide by oral gavage at the same volume.

View Article and Find Full Text PDF

Objective: To explore the character of the ICAM-1 induced change of polymorphonuclear neutrophil (PMN) in the pancreas and lung of rats with acute necrotizing pancreatitis (ANP) and to evaluate the effects of Chinese medicine WPY on ANP.

Methods: ANP model was induced by retrograde injection of 3.5% sodium taurocholic acid into the biliopancreatic duct of Wistar rats.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to examine the estrogenic effects of para-nonylphenol (p-NP) on immature SD rats and understand the mechanisms involved in its action.
  • Rats were given different doses of p-NP and estradiol benzoate (E2B) to assess their impact on uterine weight and cell signaling indicators through immunohistochemistry.
  • Results showed that p-NP increased uterine weight and the expression of progesterone and estrogen receptors, indicating that these markers may be more sensitive than just measuring uterine weight in determining estrogenic activity.
View Article and Find Full Text PDF