Smoking cessation is a protective factor for lung cancer onset and mortality: a population-based prospective cohort study.

Background: Smoking is a pivotal modifiable risk factor for lung cancer (LC). Previous studies have indicated that a smoking cessation program might be incorporated into the LC screening program. However, the effects of smoking cessation and its duration with the age at onset (AAO) of LC, all-cause mortality, and LC-specific mortality remain unclear.

Prevalence of mental disorders and their associations with age at diagnosis and time since diagnosis of nasopharyngeal cancer.

Background: Despite advancements in cancer treatment, understanding the long-term mental health implications for nasopharyngeal carcinoma (NPC) survivors remains an underexplored area. This study aims to examine the prevalence of mental disorders and their correlations with age at diagnosis and time since diagnosis among NPC survivors.

Methods: A total of 1872 NPC patients were surveyed from September 2020 to June 2021 in this cross-sectional survey.

Phase engineered amorphous-crystalline MIL-101(CuFe)@AuNPs with enhanced photothermal activity for sensitive immunochromatographic bimodal detection of streptomycin.

Phase engineering-assisted tuning of the plasma resonance properties of multifunctional nanocomposites provides an excellent opportunity to improve analytical performance. It is anticipated to break the dominating bottleneck of insufficient signal brightness in identifying imperceptible variation of the target concentration and further enhance the sensitive immunochromatographic assays (ICAs) analysis. Herein, by simply assembling isolated gold nanoparticles (AuNPs) on the surface of MIL-101(CuFe) (named MCF) with a tunable size and crystal phase, we synthesized amorphous-crystalline MCF@AuNPs nanocomposites as immuno signal tracers.

Defect-Engineering-Induced Vacancy-Rich BiS@AuNPs with Enhanced Photothermal Activity for Sensitive Bimodal-Type Gentamicin Monitoring.

One of the most promising approaches to effectively modulate the performance of immunochromatography (ICA) is the rational design of nanomaterials. It is anticipated to facilitate highly sensitive ICA analysis by introducing and controlling the internal defect structures of nanomaterials. Herein, we designed BiS@AuNPs with deep-level defect properties, revealing that these deep defects act as electron-hole nonradiative complex centers to promote phonon production, ultimately leading to photothermal analytical performance in ICA.

Joint modeling of longitudinal health-related quality of life during concurrent chemoradiotherapy period and long-term survival among patients with advanced nasopharyngeal carcinoma.

Background: To investigate the prognosis of longitudinal health-related quality of life (HRQOL) during concurrent chemoradiotherapy (CCRT) on survival outcomes in patients with advanced nasopharyngeal carcinoma (NPC).

Methods: During 2012-2014, 145 adult NPC patients with stage II-IVb NPC were investigated weekly using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire core 30 (EORCT QLQ-C30) during their CCRT period. The effects of longitudinal trends of HRQOL on survival outcomes were estimated using joint modeling, and hazard ratios (HRs) with 95% confidence intervals (95% CIs) were reported as a 10-point increase in HRQOL scores.

Drought reduces nitrogen supply and NO emission in coastal bays.

Severe droughts are increasingly prevalent under global climate change, disrupting watershed hydrology and coastal nitrogen cycling. However, the specific effects of drought on nitrogen transport from land to sea and subsequent nitrogen dynamics remain inadequately understood. In this study, we evaluated the consequences of the 2020-2022 drought on nitrogen supply and NO emissions in Xiamen Bay, Southeast China.

Enhancing the performance of organic phototransistors using a sandwich-heterostructure.

To weaken the adverse effects of traditional planar heterojunctions on phototransistors, an effective strategy for achieving low dark-current and high photoresponsive organic phototransistors constructing a sandwich heterostructure is demonstrated. This work offers a new route for the design and development of high-performance phototransistor devices.

Bulk Trapping Organic Semiconductor with Amino-Additive Enabling Ultrasensitive NO Sensors.

Organic semiconductor (OSC) gas sensors have garnered considerable attention due to their promising selectivity and inherent flexibility. Introducing a functional group or modification layer is an important route to modulate the doping/trapping state of the active layer and the gas absorption/desorption process. However, the majority of the functionalization lies in the surface/interface assembling process, which is difficult to control the functional group density.

Multi-trajectories of health-related quality of life and their associated factors in patients with nasopharyngeal carcinoma: A longitudinal study.

Background: The trajectories of health-related quality of life (HRQoL) of nasopharyngeal carcinoma (NPC) during and after the treatment along with their associated factors are seldom investigated in longitudinal studies. This study aims to investigate the longitudinal trajectories of HRQoL over time and their associated factors in patients with newly diagnosed NPC.

Methods: Between July 2018 and September 2019, a total of 500 patients were finally involved in this study.

Family context as a double-edged sword for psychological distress amid the COVID-19 pandemic with the mediating effect of individual fear and the moderating effect of household income.

Background: The COVID-19 pandemic drives psychological distress. Previous studies have mostly focused on individual determinants but overlooked family factors. The present study aimed to examine the associations of individual and family factors with psychological distress, and the mediating effect of individual fear and the moderating role of household income on the above associations.

Factors associated with willingness and preferences to attend family services in Hong Kong: A population-based survey.

Objective: Family services are open to the community at large as well as vulnerable groups; however, little is known about the willingness of communities to attend such services. We investigated the willingness and preferences to attend family services and their associated factors (including sociodemographic characteristics, family wellbeing, and family communication quality) in Hong Kong.

Methods: A population-based survey was conducted on residents aged over 18 years from February to March 2021.

Mycoviral gene integration converts a plant pathogenic fungus into a biocontrol agent.

Mycovirus-infected fungi can suffer from poor growth, attenuated pigmentation, and virulence. However, the molecular mechanisms of how mycoviruses confer these symptoms remain poorly understood. Here, we report a mycovirus Stemphylium lycopersici alternavirus 1 (SlAV1) isolated from a necrotrophic plant pathogen that causes altered colony pigmentation and hypovirulence by specifically interfering host biosynthesis of Altersolanol A, a polyketide phytotoxin.

COVID-19 pandemic fatigue and its sociodemographic and psycho-behavioral correlates: a population-based cross-sectional study in Hong Kong.

Pandemic fatigue is a growing public health concern of the lingering COVID-19 pandemic. Despite its widespread mass media coverage, systematic empirical investigations are scarce. Under the Hong Kong Jockey Club SMART Family-Link Project, we conducted online and telephone surveys amid the pandemic in February to March 2021 to assess self-reported pandemic fatigue (range 0-10) in Hong Kong adults (N = 4726) and its associations with sociodemographic and psycho-behavioral (high vs low to moderate) variables.

Skipping Breakfast and Eating Breakfast Away From Home Were Prospectively Associated With Emotional and Behavioral Problems in 115,217 Chinese Adolescents.

Background: Breakfast is deemed the most important meal of the day. We examined the prospective associations of breakfast habits with emotional/behavioral problems in adolescents and potential effect modification.

Methods: 115,217 Primary 6 students (United States Grade 6; mean age, 11.

Molecular characterization of a novel fusarivirus infecting the plant-pathogenic fungus Alternaria solani.

A novel mycovirus belonging to the proposed family "Fusariviridae" was discovered in Alternaria solani by sequencing a cDNA corresponding to double-stranded RNA extracted from this phytopathogenic fungus. The virus was tentatively named "Alternaria solani fusarivirus 1" (AsFV1). AsFV1 has a single-stranded positive-sense (+ssRNA) genome of 6845 nucleotides containing three open reading frames (ORFs) and a poly(A) tail.

Luminescent cadmium(ii) coordination polymers of 1,2,4,5-tetrakis(4-pyridylvinyl)benzene used as efficient multi-responsive sensors for toxic metal ions in water.

Reactions of Cd(NO)·4HO with 1,2,4,5-tetrakis(4-pyridylvinyl)benzene (4-tkpvb) and 5-tert-butylisophthalic acid (5-tert-HBIPA), 1,3,5-benzenetricarboxylic acid (1,3,5-HBTC) or 1,4-naphthalenedicarboxylic acid (1,4-HNDC) under solvothermal conditions afforded three two-dimensional (2D) Cd(ii) coordination polymers [Cd(4-tkpvb)(5-tert-BIPA)] (1), [{Cd(4-tkpvb)(1,3,5-HBTC)}·0.5DMF] (2) and [Cd(4-tkpvb)(1,4-NDC)] (3). Compounds 1-3 were structurally characterized by IR, elemental analysis, powder X-ray diffraction, and single crystal X-ray diffraction.

BZLF1 Attenuates Transmission of Inflammatory Paracrine Senescence in Epstein-Barr Virus-Infected Cells by Downregulating Tumor Necrosis Factor Alpha.

Unlabelled: Recent studies have shown that inflammatory responses trigger and transmit senescence to neighboring cells and activate the senescence-associated secretory phenotype (SASP). Latent Epstein-Barr virus (EBV) infection induces increased secretion of several inflammatory factors, whereas lytic infections evade the antiviral inflammatory response. However, the changes in and roles of the inflammatory microenvironment during the switch between EBV life cycles remain unknown.

Synthesis of DMF-protected Au NPs with different size distributions and their catalytic performance in the Ullmann homocoupling of aryl iodides.

DMF-stabilized Au nanoparticles (NPs) with three different particle sizes were prepared by controlling the reaction temperatures and times. In the absence of any additional ligands, these Au NPs showed high catalytic activity in the Ullmann homocoupling of aryl iodides in DMF. The effects of Au particle size on the coupling reaction were investigated by the use of three Au catalysts with mean particle sizes of ca.

Synthesis and structure of a ferric complex of 2,6-di(1H-pyrazol-3-yl)pyridine and its excellent performance in the redox-controlled living ring-opening polymerization of ε-caprolactone.

The reaction of FeCl3 with a pincer ligand, 2,6-di(1H-pyrazol-3-yl)pyridine (bppyH2), produced a mononuclear Fe(III) complex [Fe(bppyH2)Cl3] (1), which could be reduced to the corresponding Fe(II) dichloride complex [Fe(bppyH2)Cl2] (2) by suitable reducing agents such as Cp2Co or Fe powder. 1 and 2 exhibited a reversible transformation from each other with appropriate redox reagents. 1 could be utilized as a pre-catalyst to initiate the ring-opening polymerization of ε-caprolactone in the presence of alcohol but did not work.

An unprecedented octahedral {Cd30} nanocage supported by twelve pendant-armed tetraacetate macrocyclic ligands.

An unprecedented octahedral {Cd(30)} nanocage supported by twelve pendant-armed tetraacetate macrocyclic ligands was synthesized through the reaction of macrocyclic tetraethyl ester and Cd(OAc)(2)·2H(2)O in a 1 : 2 stoichiometry, where the surface photovoltage and photoluminescent properties have been studied for the nanocage.