Edge contacts offer a significant advantage for enhancing the performance of semiconducting transition metal dichalcogenide (TMDC) devices by interfacing with the metallic contacts on the lateral side, which allows the encapsulation of all of the channel material. However, despite intense research, the fabrication of feasible electrical edge contacts to TMDCs to improve device performance remains a great challenge, as interfacial chemical characterization via conventional methods is lacking. A major bottleneck in explicitly understanding the chemical and electronic properties of the edge contact at the metal-two-dimensional (2D) semiconductor interface is the small cross section when characterizing nominally one-dimensional edge contacts.
View Article and Find Full Text PDFGastric duplication cysts (GDCs) are rare cystic neoplasms that are often difficult to distinguish from other entities. Accurate diagnosis of cysts before resection is difficult even using the most advanced imaging techniques. We present a case of a gastric duplication cyst in a 17-year-old female, presenting with discomfort in the upper abdomen.
View Article and Find Full Text PDFInt Immunopharmacol
January 2025
Type 2 diabetes (T2D) is a metabolic disease, in which inflammation is a key factor. It has been well established that T cells play important role in antigen-driven immune disorders or immune defense, but were less discussed in inflammatory metabolic diseases. However, accumulating evidences suggest that CD186 (also known as CXCR6)-positive tissue infiltrating T cells might play a key role in inflammatory metabolic diseases.
View Article and Find Full Text PDFThree novel compounds, including an aromatic amino acid, dimorine A (1), a suncheonoside derivative, dimoroside A (2), and a phenylpropanoid glycoside, dimoroside B (3), together with four known compounds (4-7) were separated from Umbelopsis dimorpha VDG10, the predominant endophytic fungus found in the roots of Vaccinium dunalianum Wight (Ericaceae). Their structures were elucidated by spectroscopic methods, and the ECD spectrum confirmed the absolute configuration of 3. In addition, the antifungal activities of novel compounds against five phytopathogenic fungi were evaluated.
View Article and Find Full Text PDFThe development of two-dimensional (2D) semiconductors is limited by the lack of doping methods. We propose surface isovalent substitution as an efficient doping mechanism for 2D semiconductors by revealing the evolution of the structure and electronic properties of 2D Se/Te. Because of the different electronegativity of Se and Te, Se substitution for Te at the specific lattice sites introduces electric dipoles and leads to charge redistribution, which lowers the work function and tunes the Te films from p-type to n-type semiconductors.
View Article and Find Full Text PDFLiquid scintillator consists of an organic solvent and one or more scintillation solutes, which can emit light pulses after absorbing X- and γ-rays, or high-energy particles. It has the characteristics of strong neutron/γ-ray (n/γ) discrimination, short decay time, unlimited size and low cost, which plays an important role in high-sensitivity and large-scale radiation detection, especially in the construction and safe operation of nuclear facilities. However, the impact of solvent selection and moisture content on the fluorescence-scintillation properties of scintillators has not been adequately investigated in the literature.
View Article and Find Full Text PDFis a valuable ornamental, edible, and medicinal plant with promising prospects for bioactivity development. We screened the bioactivity of eight fractions (Fr. A-I) obtained from the ethyl acetate phase of via silica gel column chromatography.
View Article and Find Full Text PDFJ Phys Condens Matter
November 2024
Realizing novel two-dimensional (2D) magnetic states would accelerate the development of advanced spintronic devices and the understandings of 2D magnetic physics. In this paper, we have examined the magnetic and electronic properties of 20 dynamically stable and exfoliable MXO (M = Ti-Ni; X = S-Te; excluding CoTeO). It has been unveiled that [XO]-and [M]-crystal fields govern the M-3orbital splittings in MXO.
View Article and Find Full Text PDFContrary to oxide or polymeric glasses, metallic glasses are infamously known for their relatively limited thermal stability, which is often characterized by their narrow supercooled liquid regions. Nonetheless, we successfully fabricated metallic-glass based nanomembranes with an ultrahigh thermal ability by a polymer surface buckling enabled exfoliation technique. These nanomembranes exhibit a distinctive nanostructure with nanosized metallic-glasses encapsulated within an interconnected nanoamorphous-oxide network.
View Article and Find Full Text PDFFerroptosis is an iron-dependent cell death that occurs due to the peroxidation of phospholipids in the cell membrane. In this study, we find that the protein level of NSUN2 is significantly decreased in hepatocyte ferroptosis. This is attributed to STUB1-mediated ubiquitination of NSUN2 at lysines 457 and 654, promoting NSUN2 degradation in ferroptosis.
View Article and Find Full Text PDFOne-dimensional (1D) conjugated metal-organic frameworks (c-MOFs) have garnered widespread research interest in chemical energy storage and conversion. In this work, we introduce a universal principle to engineer the topological bands of 1D c-MOFs. Connected by orbitals of transition metals, two equivalent hidden molecular π orbitals in 1D c-MOFs can generate a staggered hopping within and between the organic ligands, forming Su-Schrieffer-Heeger-shaped 1D topological bands.
View Article and Find Full Text PDFEnhanced electronic coupling gives rise to many intriguing properties in π-d conjugated metal-organic frameworks (CMOFs). By low-temperature scanning tunneling microscopy and density functional theory calculation, we investigate the electronic coupling in one-dimensional (1D) π-d conjugated FeQDI polymers. Our experiments have resolved the bulk and end states stemming from Fe atoms in different coordination environments and their spatial extension due to π-d conjugation.
View Article and Find Full Text PDFResearch (Wash D C)
September 2024
Melting and solidification of lunar regolith are pivotal for comprehending the evolutionary dynamics of lunar volcanism, geology, and impact history. Additionally, insights gained from these processes can contribute to the advancement of in situ resource utilization technologies, for instance additive manufacturing and resource extraction systems. Herein, we conduct the direct observation of the melting and rapid solidification of lunar particles returned by the Chang'E 5 mission.
View Article and Find Full Text PDFBackground: The status of the sentinel lymph nodes (SLNs) is an important prognostic factor for many different types of cancer. The one-step nucleic acid amplification (OSNA) assay has emerged as a rapid intraoperative molecular diagnostic tool for LN metastasis detection. We aimed to evaluate and summarize the value of the OSNA assay for the diagnosis of SLN metastasis in cytokeratin 19 (CK19)-positive breast cancer.
View Article and Find Full Text PDFBackground And Purpose: This study aims to examine the global, regional, and national burden of ischemic stroke from 1990 to 2021.
Method: We used data from the Global Burden of Disease (GBD) 2021 database to comprehensively assess ischemic stroke indicators globally, regionally, and in 204 countries, including incidence, deaths, disability-adjusted life years (DALYs), estimated annual percentage change (EAPC), and Joinpoint regression analysis.
Results: In 2021, there were a total of 7,804,449 cases of ischemic stroke globally (95% uncertainty interval = 6,719,760-8,943,692), with an age-standardized incidence rate (ASIR) of 92.
The global climate change has resulted in substantial modifications to the distribution patterns of narrowly distributed species across different time periods, leading to an imminent threat to the survival of some vulnerable species. J. R.
View Article and Find Full Text PDFObjective: To investigate the value of intraoperative assessment of spread through air spaces (STAS) on frozen sections (FS) in peripheral small-sized lung adenocarcinoma.
Background: Surgical decision-making based on FS diagnosis of STAS may be useful to prevent local control failure after sublobar resection.
Methods: We conducted a multicenter prospective observational study of consecutive patients with cT1N0M0 invasive lung adenocarcinoma to evaluate the accuracy of FS for the intraoperative detection of STAS.
Metal-oxide interfaces with poor coherency have specific properties comparing to bulk materials and offer broad applications in heterogeneous catalysis, battery, and electronics. However, current understanding of the three-dimensional (3D) atomic metal-oxide interfaces remains limited because of their inherent structural complexity and the limitations of conventional two-dimensional imaging techniques. Here, we determine the 3D atomic structure of metal-oxide interfaces in zirconium-zirconia nanoparticles using atomic-resolution electron tomography.
View Article and Find Full Text PDFObjective: To systematically evaluate the efficacy and safety of anlotinib targeted therapy for the treatment of patients with advanced digestive system neoplasms (DSNs).
Methods: Clinical trials were extracted from PubMed, the Cochrane Library, Web of Science, Embase, China National Knowledge Infrastructure (CNKI) and the Wanfang database up to October 2023. Outcome measures, including therapeutic efficacy, quality of life (QOL) and adverse events, were extracted and evaluated.