Publications by authors named "Wei-zheng Meng"

Acute lung injury (ALI) caused by gas explosion is common, and warrants research on the underlying mechanisms. Specifically, the role of abnormalities of coagulation and fibrinolysis in this process has not been defined. It was hypothesized that the abnormal coagulation and fibrinolysis promoted ALI caused by gas explosion.

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  • This study examined the impact of infection and timing of surgery on burn healing in 318 patients with deep second-degree burns from a gas explosion in China.
  • It analyzed data, including bacterial cultures and patient outcomes, comparing those who had early (within 24 hours), middle (2-7 days), and late (>7 days) excision.
  • Results showed that early excision led to lower heart rates and faster healing, while a high percentage of bacteria found were resistant to certain antibiotics, highlighting the importance of timely medical intervention.
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  • The study focuses on lung injuries caused by gas explosions over a 20-year period, analyzing 132 cases in total.
  • Most patients showed significant complications, such as cough and hemothorax, with many suffering from additional injuries like burns and infections.
  • The findings highlight high mortality rates primarily due to respiratory failure, emphasizing the importance of timely interventions like tracheotomy and mechanical ventilation for better outcomes.
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A novel technique of three-dimensional (3D) reconstruction, segmentation, display and analysis of series slices of images including microscopic wide field optical sectioning by deconvolution method, cryo-electron microscope slices by Fourier-Bessel synthesis and electron tomography (ET), and a series of computed tomography (CT) was developed to perform simultaneous measurement on the structure and function of biomedical samples. The paper presents the 3D reconstruction segmentation display and analysis results of pollen spore, chaperonin, virus, head, cervical bone, tibia and carpus. At the same time, it also puts forward some potential applications of the new technique in the biomedical realm.

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