Publications by authors named "Wei-wei Gong"
Article Synopsis
- The study aimed to evaluate the accuracy of FreeStyle Libre Pro (FSL-Pro) continuous glucose monitoring (CGM) in patients with type 2 diabetes and acute myocardial infarction.
- A total of 97 patients participated, undergoing blood glucose tests and CGM, revealing that CGM indicated significantly lower average blood glucose levels compared to traditional finger-prick tests, especially in the first day.
- The results also showed that while CGM detected more instances of hypoglycemia, there was noted variability in its results compared to finger-prick testing, though a strong correlation between the two methods was established.
Objective: This study aimed to quantify the severity of metabolic syndrome(MetS) and investigate its association with cardiovascular disease(CVD) risk on Chinese adults.
Methods: 13,500 participants from the Zhejiang Adult Chronic Disease Study were followed up between 2010 and 2021. A continuous MetS severity score derived from the five components of MetS was used to quantify MetS severity, and the association between MetS severity and the risk of incident CVD was assessed using Cox proportional hazard and restricted cubic spline regression.
Increased bacterial drug resistance has become a serious global public health problem. The application of antibiotics involves various clinical departments, and the rational application of antibiotics is the key to improving their efficacy. To provide a basis for further improving the etiological submission rate and standardizing the rational use of antibiotics, this article discusses the intervention effect of multi-department cooperation in improving the etiological submission rate before antibiotic treatment.
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- RORα is a type of nuclear hormone receptor that plays a significant role in the cardiovascular system by influencing various processes like inflammation and oxidative stress, which are crucial in heart-related diseases.
- The review highlights both the protective effects of RORα in conditions like atherosclerosis and hypertension, as well as the current advancements and challenges in developing RORα-based therapies.
- Future progress in creating effective RORα-related drugs could benefit from interdisciplinary research to overcome limitations in translating lab findings into clinical treatments.
Backgrounds: Cancer is one of the main causes of death worldwide, seriously threatening human health and life expectancy. We aimed to analyze the cancer incidence and mortality rates during 2016 in Zhejiang Province, Southeast China.
Methods: Data were collected from 14 population-based cancer registries across Zhejiang Province of China.
Article Synopsis
- A study conducted in Zhejiang Province, China, explored the link between diabetes and thyroid cancer risk, involving 2,937 thyroid cancer cases matched with 2,937 healthy controls from 2015 to 2017.
- The study found that overall, there was no significant association between diabetes or its duration and thyroid cancer risk.
- However, in certain groups (older adults, females, overweight/obese individuals, and those with a family history of diabetes), shorter diabetes duration (≤ 5 years) was linked to a lower risk of developing thyroid cancer.
Objective: To investigate the sleep duration and correlates from lifestyle, dietary and weight control behaviors in Chinese adolescents.
Methods: Data were from 2017 Zhejiang Youth Risk Behavior Survey. A total of 17059 adolescents were included in this study and sleep duration and other behaviors information was collected via a self-reported questionnaire.
Background: Limited population-based studies have investigated the secular trend of prevalence of gestational diabetes mellitus (GDM) in mainland China. Therefore, this study aimed to estimate the prevalence of GDM and time trends in Chinese female population.
Methods: Based on Diabetes Surveillance System of Zhejiang Province, 97,063 diagnosed GDM cases aged 20-50 years were identified from January 1, 2016 to December 31, 2018.
Article Synopsis
- - The study investigated the relationship between reproductive factors, such as menstrual history and breastfeeding, and thyroid cancer risk in Chinese women, finding inconsistent results in prior research.
- - Data was collected through a matched case-control study involving 2,261 pairs of female subjects, with analysis done using logistic regression to determine odds ratios for thyroid cancer risk.
- - The results indicated that a later age at first pregnancy and longer breastfeeding duration were linked to a reduced risk of thyroid cancer, particularly in women aged 50 or younger.
Dihydromyricetin (DHY), a flavonoid component isolated from Ampelopsis grossedentata, exerts versatile pharmacological activities. However, the possible effects of DHY on diabetic vascular endothelial dysfunction have not yet been fully elucidated. In the present study, male C57BL/6 mice, wild type (WT) 129S1/SvImJ mice and sirtuin 3 (SIRT3) knockout (SIRT3) mice were injected with streptozotocin (STZ, 60 mg/kg/day) for 5 consecutive days.
View Article and Find Full Text PDFIntroduction: Previous research has indicated that weight control behaviors are linked to cigarette smoking, whether these relationships extend to electronic cigarettes (e-cigarettes) is unknown. This study aims to examine the association between weight control behaviors and current e-cigarette usage among middle and high school students in China.
Methods: Based on the 2017 Zhejiang Youth Risk Behavior Survey, 17359 students were included and relevant data involving e-cigarette and weight control behaviors were collected via self-reported questionnaires.
Aims: Population-based incidence data are paramount to assess the effects of prevention strategies for diabetes, yet the relevant studies in mainland China are scarce. This study is aimed at estimating the type 2 diabetes mellitus (T2DM) incidence and time trends in Chinese adults. .
View Article and Find Full Text PDFObjectives: The present study aims at examining the prevalence of awareness and current use of electronic cigarettes (e-cigarettes) among middle and high school students from Zhejiang, China. Smoking-related factors associated with e-cigarettes use will also be explored.
Methods: This cross-sectional study was based on 2017 Zhejiang Youth Risk Behavior Survey.
Analysis of Mortality and Survival Rate of Liver Cancer in Zhejiang Province in China: A General Population-Based Study.
Can J Gastroenterol Hepatol
March 2020
Background: Few accurate up-to-date studies provide liver cancer mortality and survival information in Zhejiang province. This research aimed to depict the mortality and survival of liver cancer in Zhejiang province in China during 2005-2010.
Methods: The data were collected from the Zhejiang Chronic Disease Surveillance Information and Management System, and the mortality rates of liver cancer were calculated by gender, age, and areas.
Aims/introduction: Evidence has shown that stressful life events are associated with the development of diabetes, yet studies in mainland China are scarce. In the present study, we explored the associations between cumulative and specific stressful life events and the prevalence of diabetes in Chinese adults.
Materials And Methods: The cross-sectional data were from the China Kadoorie Biobank study, which enrolled approximately 500,000 adults aged 30-79 years from 10 diverse regions of China.
Article Synopsis
- - The study aimed to identify factors affecting the age at natural menopause among over 17,000 postmenopausal Chinese women as part of the China Kadoorie Biobank research.
- - It found the average age at onset of natural menopause was around 48.94 years, with specific lifestyle and demographic factors influencing whether menopause occurred early or late.
- - Key associations included that higher education, moderate meat consumption, and having more children generally led to later menopause, while smoking, being underweight, and a high activity level were linked to earlier menopause.
Article Synopsis
- * Researchers analyzed data from over 17,000 women and found that 7.54% had type 2 diabetes.
- * Results indicated that women who experienced menopause later (≥53 years) were 1.21 times more likely to have diabetes compared to those who underwent menopause between 46-52 years.
Background: Life expectancy is a statistical measure of the average time an organism is expected to live. The purpose of this study was to evaluate the impact of injury-related mortality on life expectancy in Zhejiang Province.
Methods: Our study used standard life tables to calculate life expectancy and cause-removed life expectancy based on mortality data from the Zhejiang Chronic Disease Surveillance System.
Article Synopsis
- The study aimed to assess the links between sleep duration, snoring, and diabetes among different gender and menopausal status groups in rural China.
- Researchers analyzed data from over 57,000 participants aged 30-79 using logistic regression to determine the odds of diabetes based on sleep patterns and snoring.
- Results indicated a U-shaped relationship between sleep duration and diabetes risk in postmenopausal women, while snoring was associated with diabetes across all groups, impacted by factors like socioeconomic status and health behaviors.*
Evidence indicates that breakfast consumption is associated with a cluster of health-related behaviors, yet studies in mainland China are scarce. This study is conducted to describe the frequency of breakfast consumption among Chinese adolescents and examine its associations with other dietary, physical activity, sedentary, sleep, cigarette-smoking, and alcohol-drinking behaviors. Breakfast consumption and other health-related behaviors data was collected via a self-administered questionnaire in a cross-sectional study in Zhejiang Province, China.
View Article and Find Full Text PDFThe microRNA-21 (miR-21) is known to play a major role in cancer progression; however, its function in the cardiovascular system appears to be even more complex and conflicting. To characterize miR-21 expression in the plasma of individuals with or without metabolic syndrome (MetS), 58 MetS cases and 96 non-MetS controls were investigated. Expression levels of miR-21 were significantly decreased in the circulation of MetS subjects (OR=0.
View Article and Find Full Text PDFEvidence indicates an increased cancer risk among type 2 diabetes mellitus (T2DM) patients, yet studies in mainland China are scarce. Based on Diabetes Surveillance System linking to Cancer Surveillance System of Zhejiang Province in China, we explored the cancer risk among T2DM patients. Totally, 327,268 T2DM patients were identified and followed from January 1, 2007 to December 31, 2013.
View Article and Find Full Text PDFGeographic distribution and epidemiology of lung cancer during 2011 in Zhejiang province of China.
Asian Pac J Cancer Prev
April 2015
Background: To explore etiology for providing scientific clues for the prevention of lung cancer.
Materials And Methods: Data for lung cancer incidence and meteorological geographic factors from 25 counties in Zhejiang province of China during 2011 were studied. Stepwise multiple regression and correlation analysis were performed to analyze the geographic distribution and epidemiology of lung cancer.
Background: Whether cigarette smoking and alcohol consumption are associated with the risk of metabolic syndrome (MetS) remains controversial. This study investigated the associations of cigarette smoking and alcohol consumption with MetS in a male population in China.
Methods: We conducted a cross-sectional study.
[Survival rate of colorectal cancer patients during 2005-2010 in Zhejiang province, China].
Zhonghua Liu Xing Bing Xue Za Zhi
December 2013
Objective: To analyze the survival rate of colorectal cancer, using data from the population-based cancer registry during 2005-2010 in Zhejiang.
Methods: The last follow-up activities on 17 235 cases regarding the survival status was December 31, 2012. Both cumulative observed survival rate (OS) and relative survival rate (RS) were calculated with SURV 3.