Publications by authors named "Wei-wei Fu"

Article Synopsis
  • Chakouyi (CKY) horses from the Qinghai‒Xizang Plateau are specifically noted for their unique gaits and adaptations to high altitudes, but the genetic reasons behind these traits are still not well understood.
  • A study analyzed the genomes of CKY horses and other horse breeds, finding CKY horses genetically closer to other highland breeds and showing signs of reduced genetic diversity and lower inbreeding, likely due to selective pressures.
  • The research identified a key mutation in the DMRT3 gene linked to CKY's lateral gaits and highlighted the importance of the EPAS1 and CAT genes for high-altitude resilience, suggesting that preserving genetic diversity is crucial for maintaining these unique traits in CKY horses
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Predation is widely recognized as a powerful selective pressure on primate behavior and ecology, although knowledge of predator-prey relationships remains limited partly due to the rarity of directly observed attacks on primates. Here, we describe four confirmed or suspected instances of leopard (Panthera pardus) predation on free-ranging Sichuan (golden) snub-nosed monkeys (Rhinopithecus roxellana), a highly endangered colobine species endemic to China. We recorded predation events and the reactions of monkey group members.

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Understanding how evolutionary pressures related to climate change have shaped the current genetic background of domestic animals is a fundamental pursuit of biology. Here, we generated whole-genome sequencing data from native goat populations in Iraq and Pakistan. Combined with previously published data on modern, ancient (Late Neolithic to Medieval periods), and wild species worldwide, we explored the genetic population structure, ancestry components, and signatures of natural positive selection in native goat populations in Southwest Asia (SWA).

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Background: The gastric microbiota in patients with gastric cancer (GC) has received increasing attention, but the profiling of the gastric microbiome through the histological stages of gastric tumorigenesis remains poorly understood, especially for patients with -negative GC (HPNGC).

Aim: To characterize microbial profiles of gastric mucosa and juice for HPNGC carcinogenesis and identify distinct taxa in precancerous lesions.

Methods: The 16S rRNA gene analysis was performed on gastric mucosa from 134 -negative cases, including 56 superficial gastritis (SG), 9 atrophic gastritis (AG), 27 intestinal metaplasia (IM), 29 dysplasia (Dys), and 13 GC cases, to investigate differences in gastric microbial diversity and composition across the disease stages.

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Background: Morule-like component (MLC) was a rare structure in primary lung adenocarcinoma. We aimed to reveal the clinicopathological, radiological, immunohistochemical, and molecular features of lung adenocarcinoma with MLCs.

Methods: Twenty lung adenocarcinomas with MLCs were collected, and computed tomographic and histological documents were reviewed.

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Background: Lymphangiomatosis is a multisystem disorder that is rarely localized to the gastrointestinal tract. Lymphangiomatosis usually has no specific clinical presentation and is easily misdiagnosed. A case report and review of the literature on lymphangiomatosis associated with protein-losing enteropathy will help to improve the overall understanding of this disease.

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We previously showed that different skeletal muscles in Daurian ground squirrels () possess different antioxidant strategies during hibernation; however, the reason for these varied strategies remains unclear. To clarify this issue, we studied REDD1, FOXO4, PGC-1α, FOXO1 and atrogin-1 proteins to determine the potential cause of the different antioxidant strategies in Daurian ground squirrels during hibernation, and to clarify whether different strategies affect atrophy-related signals. Results showed that the soleus (SOL) muscle experienced intracellular hypoxia during interbout arousal, but no oxidative stress.

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Background: Enteropathy-associated T-cell lymphoma (EATL) is a rare invasive lymphoma derived from gastrointestinal epithelial T lymphocytes. EATL involving the whole gastrointestinal tract accompanied with early colon cancer is extremely rare.

Case Summary: We present the case of a 67-year-old man with diarrhea for more than 5 mo whose colonoscopy in another hospital showed multiple colonic polyps, which indicated moderate to severe dysplasia and focal early cancer.

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We previously showed that different skeletal muscles in Daurian ground squirrels (Spermophilus dauricus) possess different antioxidant strategies during hibernation; however, the reason for these varied strategies remains unclear. To clarify this issue, we studied REDD1, FOXO4, PGC-1α, FOXO1, and atrogin-1 proteins to determine the potential cause of the different antioxidant strategies in Daurian ground squirrels during hibernation, and to clarify whether different strategies affect atrophy-related signals. Results showed that the soleus (SOL) muscle experienced intracellular hypoxia during interbout arousal, but no oxidative stress.

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Purpose: To retrospectively analyze the clinical characteristics of impacted supernumerary teeth in 115 patients.

Methods: One hundred and fifteen patients with im-pacted supernumerary teeth who were admitted to the Department of Oral and Max-illofacial Surgery of Hefei Stomatological Hospital were selected randomly. The age, sex, number of teeth, location, direction, clinical manifestation, anaes-thesia method and operation time were analyzed retrospectively, T test and Chi-square test were used to determine the statistical differences with SPSS 19.

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Golden snub-nosed monkeys (), as typical arboreal group-living Old World monkeys, provide an appropriate animal model to research manual laterality and explore the factors affecting hand preference in nonhuman primates. This study investigated hand preference based on 63 subjects and four spontaneous manual tasks (including unimanual and bimanual feeding and grooming), and assessed the effects of age, gender and type of task on handedness in . A population-level left-handedness was found not only in the bimanual coordinated tasks (bimanual feeding and grooming), but also in one unimanual reaching task (unimanual feeding).

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Two new coordination polymers, namely, poly[[μ-3-(1-benzimidazol-2-yl)propionato]zinc(II)], [Zn(CHNO)] , (), and poly[bis-[μ-3-(1-benzimid-azol-2-yl)propionato]cadmium(II)], [Cd(CHNO)] , () have been synthesized from 3-(1-benzoimidazol-2-yl)propanoic acid ligands through a mixed-ligand synthetic strategy under a solvothermal environment, and studied by single-crystal X-ray diffraction. Complex crystallizes in the ortho-rhom-bic space group and features a two-dimensional structure formed by a binuclear ZnO core. Complex , however, crystallizes in the monoclinic space group 2/ and forms a one-dimensional chain structure.

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A new complex, namely bis-[4'-(furan-2-yl)-2,2':6',2''-terpyridine]-nickel(II) dichloride deca-hydrate, [Ni(CHNO)]Cl·10HO, has been crystallized by solvent evaporation and characterized by single-crystal X-ray diffraction. The coordination environment of the Ni cation is distorted octa-hedral with slight deviations from an idealized geometry. The most intriguing structural feature is an infinite two-dimensional hybrid water-chloride network parallel to (011) constructed by O-H⋯O and O-H⋯Cl hydrogen bonds involving two independent chloride ions and ten independent solvent water mol-ecules with an l-shaped pattern.

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Objective: We analyzed a case of medulloblastoma with atypical dynamic imaging changes retrospectively to summarize the atypical magnetic resonance imaging (MRI) features of medulloblastoma by reviewing the literature.

Methods: An atypical case of medulloblastoma in the cerebellar hemisphere confirmed by pathology was analyzed retrospectively, and the literature about it was reviewed.

Results: The radiologic findings of the patient were based on 3 examinations.

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The bifunctional pyridine-2,3-dicarboxylic acid (Hpdc) ligand has one N atom and four O atoms, which could bind more than one Ag centre with diverse binding modes. A novel infinite one-dimensional Ag coordination polymer, namely catena-poly[[silver(I)-(μ-pyridine-2,3-dicarboxylato-κN:O)-silver(I)-tris(μ-5-methyl-1,3,4-thiodiazol-2-amine-κN:N')] monohydrate ethanol monosolvate], {[Ag(CHNO)(CHNS)]·HO·CHOH}, has been synthesized using Hpdc and 5-methyl-1,3,4-thiadiazol-2-amine (tda), and characterized by single-crystal X-ray diffraction. One Ag atom is located in a four-coordinated AgN tetrahedral geometry and the other Ag atom is in a tetrahedral AgNO geometry.

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We compared the effects of hibernation inactivity and 14-day hindlimb unloading in non-hibernating period on biochemical, rheological, and hematological parameters of blood in Daurian ground squirrels (Spermophilus dauricus). Twenty-four squirrels were randomly divided into four groups: control (CON), hibernation (HIB), post-hibernation (POST), and 14-day hindlimb unloading (HU). The results showed that serum enzymes (L-lactate dehydrogenase, alanine aminotransferase, and aspartate aminotransferase) activities decreased in HIB, POST, and HU squirrels compared with CON.

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The design and synthesis of functional coordination polymers is motivated not only by their structural beauty but also by their potential applications. Zn(II) and Cd(II) coordination polymers are promising candidates for producing photoactive materials because these d(10) metal ions not only possess a variety of coordination numbers and geometries, but also exhibit luminescence properties when bound to functional ligands. It is difficult to predict the final structure of such polymers because the assembly process is influenced by many subtle factors.

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From the viewpoint of crystal engineering, the construction of crystalline polymeric materials requires a rational choice of organic bridging ligands for the self-assembly process. Multicarboxylate ligands are of particular interest due to their strong coordination activity towards metal ions, as well as their various coordination modes and versatile conformations. The structural chemistry of dicarboxylate-based coordination polymers of transition metals has been developed through the grafting of N-containing organic linkers into carboxylate-bridged transition metal networks.

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The design and preparation of crystalline polymeric materials has attracted increasing attention due to their diverse applications as functional materials in gas storage, separation, catalysis, sensing and photoluminescence. The judicious selection of organic linkers is critical for varying the coordination behaviour of the metal ions and determining the overall characteristics of the networks. A new adenine-based Zn(II) coordination polymer, [Zn(C6H2O4S)(C5H5N5)]n or [Zn(tdc)(9H-ade)] (H2tdc is thiophene-2,5-dicarboxylic acid and ade is adenine), has been prepared hydrothermally and the crystal structure exhibits in its packing two-dimensional (4,4) grid sheets parallel to the ab plane, featuring two distinct square cavities delimited by the two types of ligands and the Zn(II) ions with the dimensions 6.

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The vitellogenin receptor (VgR) plays a key role on embryonic development in oviparous animals. Here, we cloned a VgR gene, which was identified from the wild silkworm Bombyx mandarina (BmaVgR) using reverse transcriptase polymerase chain reaction (RT-PCR) and rapid amplification of cDNA ends (RACE). Sequence analysis revealed that BmaVgR is 5,861 bp long with an open reading frame encoded by 1,811 amino acid residues.

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The title compound, C20H14N4, is a new polymorph of the previously reported structures, which were ortho-rhom-bic, space group Pbca [Bei et al. (2000). Acta Cryst.

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Insects possess an innate immune system that responds to invading microorganisms. In this study, a subtractive cDNA library was constructed to screen for immune response-related genes in the fat bodies of Antheraea pernyi (Lepidoptera: Saturniidae) pupa challenged with Escherichia coli. Four hundred putative EST clones were identified by suppression subtractive hybridization (SSH), including 50 immune response-related genes, three cytoskeleton genes, eight cell cycle and apoptosis genes, five respiration and energy metabolism genes, five transport genes, 40 metabolism genes, ten stress response genes, four transcription and translation regulation genes and 77 unknown genes.

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Synopsis of recent research by authors named "Wei-wei Fu"

  • - Wei-Wei Fu's research primarily focuses on the ecological interactions and adaptive behaviors of primates, particularly emphasizing the effects of predator-prey dynamics, as evidenced by documented instances of leopard predation on the endangered Sichuan snub-nosed monkeys.
  • - Additional studies by Fu explore habitat alterations and their influence on the dispersal behaviors of golden snub-nosed monkeys, highlighting the complex interplay between environmental changes and primate adaptability in the Qinling Mountains, China.
  • - Fu's work encompasses broader biological investigations, including the genomic analysis of indigenous goat populations in Southwest Asia, revealing ancient adaptive traits linked to desert climates, which provides insights into evolutionary pressures faced by domestic animals in response to climate change.

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