Prevalence and risk factors of peripheral arterial disease in diabetic patients over 50 years old in China.

Objective: To investigate the prevalence of peripheral arterial disease (PAD) in China type 2 diabetic patients and to demonstrate the relationships between putative risk factors and PAD.

Methods: In total 1,397 type 2 diabetic patients aged 50 years and older were enrolled and determined ankle-brachial index (ABI) and brachial-ankle pulse wave velocity (baPWV) in 15 Class III Grade A hospitals in 7 major cities of China.

Results: Mean patient age was 63.

[Analysis of peripheral arterial obstructive disease related factors among diabetic population aged > or = 50].

Objective: To analyze the peripheral arterial obstructive disease (PAD) related factors among diabetic population aged > or = 50 in China.

Methods: The clinical data of 1397 diabetic patients aged > or = 50 with at least one of the following risk factors: smoking, hypertension, and hyperlipidemia, from 15 Class III Grade A hospitals in 7 major cities of China were collected. Diagnosis of PAD was based on the ankle brachial index (ABI) < 0.

[Effects of captopril on myocardial tissue energy metabolism and inflammation in rats with diabetic cardiomyopathy].

Objective: To study the protective mechanism of captopril in diabetic cardiomyopathy by means of DNA microarray.

Methods: Rat models of diabetic cardiomyopathy were divided into test and control groups (n=5), and the rats in the test group were given oral captopril (1.5 mg/kg b.

[Expression of energy metabolism-related genes in myocardial tissues of rats with diabetic cardiomyopathy].

Objective: To study the pathogenesis of diabetic cardiomyopathy using DNA microarray.

Methods: Experimental rats were grouped into a diabetic cardiomyopathy and a normal control group. The cDNA probes were prepared by labeling the mRNA extracted from normal tissue and tissue of diabetic cardiomyopathy with Cy3-dUTP and Cy5-dUTP respectively through reverse transcription.