CdSe/TiONTs Heterojunction-Based Nonenzymatic Photoelectrochemical Sensor for Glucose Detection.

Compared with a single semiconductor, the heterojunction formed by two different semiconductors usually has higher light utilization and better photoelectric performance. By using stable TiO nanotubes as the main subject, CdSe/TiONTs heterojunctions were synthesized by a hydrothermal method. XRD, TEM, SEM, PL, UV-vis, and EIS were used to characterize the fabricated CdSe/TiONTs.

[Exploration of the theory of pulse method recorded in the ].

pulse method is one of the classical pulse methods of acupuncture-moxibustion in the , which is also a classical clinical paradigm for diagnosing and treating meridian diseases in the ancient times. Based on comprehensive review of literature and clinical practice, this paper reveals that this method compares the size of the neck pulse with hand pulse to determine the change of and excess-deficiency identifying the affected meridians. The -well, -spring, and -stream points of the surface and interior meridians of affected meridians are mainly selected to regulate deficiency and excess through reinforcing and reducing methods.

CdS-Modified TiO Nanotubes with Heterojunction Structure: A Photoelectrochemical Sensor for Glutathione.

The formation of heterojunction structures can effectively prevent the recombination of photogenerated electron-hole pairs in semiconductors and result in the enhancement of photoelectric properties. Using TiO nanotubes (prepared using the hydrothermal-impregnation method) as carriers, CdS-TiONTs were fabricated as a photoelectrochemical (PEC) sensor, which can be used under visible light and can exhibit good PEC performance due to the existence of the heterojunction structure. The experimental results show that the prepared CdS-TiONTs electrode had a linear response to 2-16 mM glutathione (GSH).

Job-related stress associated with work-related upper extremity musculoskeletal disorders (UEMDs) in municipal waste collectors: the moderation and mediation effect of job support.

Background: Since the policy of "keeping trash off of the ground" in Taiwan, long-term exposure to repetitive motion in waste collection process results in high risk of upper extremity musculoskeletal disorders (UEMDs). Thus, we assessed the moderation and mediation effects of job-related stress and job support on work-related UEMDs among municipal waste collectors.

Methods: A cross-sectional study was conducted in two cities located at northern Taiwan during 2018-2019.

Moderating and Mediating Effects of Over-Commitment on the Association Between Effort-Reward Imbalance (ERI) with Upper Back and Hand/Wrist Disorders in Municipal Solid Waste Collectors.

Purpose: Despite repetitive activities and the frequency of high workload for municipal solid waste (MSW) collectors, the risks of work-related stress on upper extremity pain are inconclusive. The objective of this study is to assess the moderation and mediation effect of effort-reward imbalance (ERI) and over-commitment (OC) on upper back and hand/wrist disorders in MSW collectors.

Methods: A cross-sectional study was conducted with MSW collectors from two cities in Taiwan.

Two CRISPR/Cas9 Systems Developed in Thermomyces dupontii and Characterization of Key Gene Functions in Thermolide Biosynthesis and Fungal Adaptation.

, a widely distributed thermophilic fungus, is an ideal organism for investigating the mechanism of thermophilic fungal adaptation to diverse environments. However, genetic analysis of this fungus is hindered by a lack of available and efficient gene-manipulating tools. In this study, two different Cas9 proteins from mesophilic and thermophilic bacteria, with expression of a single guide RNA (sgRNA) under the control of tRNA, were successfully adapted for genome editing in We demonstrated the feasibility of applying these two gene editing systems to edit one or two genes in The mesophilic CRISPR/Cas9 system displayed higher editing efficiency (50 to 86%) than the thermophilic CRISPR/Cas9 system (40 to 67%).

PI3K-Akt-mTOR inhibition by GNE-477 inhibits renal cell carcinoma cell growth and .

Sustained activation of PI3K-Akt-mTOR cascade is important for renal cell carcinoma (RCC) cell progression. GNE-477 is a novel and efficacious PI3K-mTOR dual inhibitor. The current study tested its anti-RCC cell activity.

[Therapeutic effect of tadalafil on lower urinary tract symptoms with erectile dysfunction].

Objective: To investigate the therapeutic effect of low-dose tadalafil on BPH-induced lower urinary tract symptoms (LUTS) complicated with ED.

Methods: We randomly assigned 126 patients with BPH-induced LUTS and ED to receive daily administration of tadalafil (5 mg) plus tamsulosin hydrochloride sustained-release capsules (0.2 mg) (treatment group Ⅰ ［T-Ⅰ］, n = 42), tadalafil (5 mg) only (treatment group Ⅱ ［T-Ⅱ］, n = 42) or placebo (control group, n = 42), all for 12 weeks.

Left atrial appendage orifice diameter measured with trans-esophageal echocardiography is independently related with peri-device leakage after Watchman device implantation.

Percutaneous left atrial appendage closure (LAAC) has emerged as an alternative of stroke prevention in non-valvular atrial fibrillation (NVAF) patients. Peri-device leakage after LAAC is common. This retrospective, case-control study aimed to identify risk factors related with peri-device leakage after LAAC with Watchman devices.

Role of Soluble ST2 Levels and Beta-Blockers Dosage on Cardiovascular Events of Patients with Unselected ST-Segment Elevation Myocardial Infarction.

Background: Serum soluble ST2 (sST2) levels are elevated early after acute myocardial infarction and are related to adverse left ventricular (LV) remodeling and cardiovascular outcomes in ST-segment elevation myocardial infarction (STEMI). Beta-blockers (BB) have been shown to improve LV remodeling and survival. However, the relationship between sST2, final therapeutic BB dose, and cardiovascular outcomes in STEMI patients remains unknown.

LncRNA THOR promotes human renal cell carcinoma cell growth.

Background: Recent studies have characterized a novel but extremely conserved long non-coding RNA (LncRNA) THOR. THOR directly associates with insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) to promote mRNA stabilization of key pro-cancerous genes.

Results: Here, we show that THOR is expressed in human renal cell carcinoma (RCC) tissues and established/primary human RCC cells.

Efficacy and Safety of the WATCHMAN Left Atrial Appendage System for Stroke Prevention in Chinese Patients with Nonvalvular Atrial Fibrillation: A Single-center, Prospective, Observational Study.

Background: In patients with nonvalvular atrial fibrillation (NVAF), embolic stroke is thought to be associated with left atrial appendage (LAA) thrombi. The WATCHMAN LAA Occlusion Device has been shown to be noninferior to conventional oral anticoagulation with warfarin for stroke prevention in patients with NVAF. This study aimed to evaluate the procedural feasibility, safety and 12-month outcomes of the WATCHMAN LAA Occlusion Device in NVAF patients with high risk for stroke in China.

Huperzine A protects sepsis associated encephalopathy by promoting the deficient cholinergic nervous function.

Neuroinflammatory deregulation in the brain plays a crucial role in the pathogenesis of sepsis associated encephalopathy (SAE). Given the mounting evidence of anti-inflammatory and neuroprotective effects of the cholinergic nervous system, it is surprising that there is little information about its changes in the brain during sepsis. To elucidate the role of the cholinergic nervous system in SAE, hippocampal choline acetyltransferase, muscarinic acetylcholine receptor-1, acetylcholinesterase and acetylcholine were evaluated in LPS-induced sepsis rats.

Electrically-pumped plasmonic lasers based on low-loss hybrid SPP waveguide.

A low-loss surface plasmonic polariton (SPP) laser is designed as a candidate for the light-source in large-scale integrated (LSI) photonic circuits. Key design parameters of the laser are discussed and optimized to enhance the optical gain and minimize the metallic absorption loss. Performance of the laser is calculated to verify the device feasibility in the designed application.

Electro-optical phase-change 2 × 2 switching using three- and four-waveguide directional couplers.

Theoretical modeling and numerical simulation have been performed at λ=2100  nm on silicon-on-insulator channel-waveguide directional couplers in which the outer two Si waveguides are passive and the central waveguide(s) are electro-optical (EO) "islands." The EO channel(s) utilize a 10 nm layer of Ge2Sb2Te5 phase-change-material sited at midlevel of a doped Si channel. A voltage-driven phase change produces a large change in the effective index of the TE(o) and TM(o) modes, thereby inducing crossbar 2×2 switching.

Electro-optical switching at 1550 nm using a two-state GeSe phase-change layer.

New designs for electro-optical free-space and waveguided 2 x 2 switches are presented and analyzed at the 1.55 μm telecoms wavelength. The proposed devices employ a ~10 nm film of GeSe that is electrically actuated to transition the layer forth-and-back from the amorphous to the crystal phase, yielding a switch with two self-sustaining states.

Long range mid-infrared propagation in Si and Ge hybrid plasmonic-photonic nano-ribbon waveguides.

We have investigated a hybrid plasmonic-photonic mode in Si and Ge channel waveguides over the 1.55-8.0 μm wavelength range.

[Brief discussion on the life of ZENG Tian-zhi, a follower of Chengjiang acupuncture school].

ZENG Tian-zhi, as one of the disciples of Mr. CHENG Dan-an, is considered as one of the major successors of the Chengjiang acupuncture school in the South of the Five Ridges. By collecting Mr.

Insights into complex Berenger modes: a view from the weighted optical path distance perspective.

We present a simple and efficient approach for higher-order Berenger mode computation. We establish the physical mapping between radiation modes and complex Berenger modes, and theoretically prove that the higher-order substrate Berenger modes and cladding Berenger modes can converge to a cluster of complex modes with the same phase angle. This model can be explained by weighted optical path distance in both cladding and substrate, and can be implemented by adjusting parameters of perfectly matched layers.

[Results of different postoperative adjuvant therapies for stage Ib-IIa cervical carcinoma with risk factors].

Objective: To investigate the effects of postoperative adjuvant chemotherapy (CT) and chemoradiotherapy (CRT) or radiotherapy(RT) for Ib-IIa cervical cancer with risk factors.

Methods: From March 1995 to June 2010, there were 137 patients underwent radical hysterectomy and systematic pelvic lymphadenectomy for stage Ib-IIa cervical cancer admitted at Peking University First Hospital. These patients had risk factors, intermediate risk factors including bulky tumor ( > 4 cm) , lymph vascular space invasion, deep stromal invasion; high risk factors including positive surgical margin, parametrial invasion, lymph node involvement.

[Procalcitonin change pattern in patients with septic shock and its relationship with prognosis].

Objective: To investigate procalcitonin (PCT) change pattern in patients with septic shock and its relationship with prognosis.

Methods: Sixty-three septic shock patients were enrolled, and levels of PCT, C-reactive protein (CRP) as well as white blood cell (WBC) on 1st, 3rd, 5th,7th day after admission to intensive care unit (ICU) were checked. Patients were divided into survival group and death group according to 28-day survival result.

[Distribution and antibiotic resistance of bacteria causing bloodstream infections in patients in intensive care unit].

Objective: To investigate the distribution and antibiotic resistance of bacteria causing bloodstream infections in intensive care unit (ICU) patients and to provide a basis for rational clinical use of antibiotics.

Methods: The data of positive specimens, including whole blood, catheter blood and bone marrow samples, were isolated from ICU patients from January 2010 to December 2012. Disc diffusion method, micro-dilution and Etest method were used to test drug sensitivity.

[Clinical value of extravascular lung water and preload parameters in weaning of mechanical ventilation in patients with septic shock].

Objective: To investigate the values of extravascular lung water and preload parameters of weaning from mechanical ventilation on patients with septic shock.

Methods: A prospective study was conducted. A total of 52 septic shock patients with mechanical ventilation were enrolled from January 2010 to July 2012.

WNT10A plays an oncogenic role in renal cell carcinoma by activating WNT/β-catenin pathway.

Renal cell carcinoma (RCC) is a malignancy with poor prognosis. WNT/β-catenin signaling dysregulation, especially β-catenin overactivation and WNT antagonist silencing, is associated with RCC carcinogenesis and progression. However, the role of WNT ligands in RCC has not yet been determined.

[Significance of serum procalcitonin levels in the evaluation of severity and prognosis of patients with systemic inflammatory response syndrome].

Objective: To observe the dynamic changes in serum procalcitonin (PCT), C-reactive protein (CRP), and white blood cell (WBC) count in systemic inflammatory response syndrome (SIRS) and their implication in assessment of illness severity and prognosis.

Methods: A prospective case control study was conducted. Seventy-two patients with SIRS in Guangdong General Hospital were enrolled in intensive care unit (ICU) from May, 2010 to June, 2011.