Publications by authors named "Wei-ni Ou"

Background And Aim: With the changes in diet structure and lifestyle, the incidence of fatty liver disease is increasing in China, especially in cities. The goal of the present study was to accurately determine the prevalence and risk factors of fatty liver disease in Beijing residents, China.

Methods: By using random multistage stratification and cluster sampling, residents aged > 20 years in Dongcheng District and Tongzhou District were recruited, and questionnaire survey, physical examination, detection of fasting glucose, blood lipids and liver biochemistry, and ultrasonography of the liver, gallbladder, and spleen were carried out.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to assess the effectiveness of interferon (IFN) retreatment in chronic hepatitis C patients who relapsed after prior IFN therapy, focusing on various influencing factors.
  • Significant results indicated that PEG-IFNalpha-2a treatment led to higher end of treatment virus response (ETVR) and sustained viral response (SVR) rates compared to CIFNalpha-2a, particularly in patients with genotype 1.
  • Overall, while some patients did not respond to retreatment, PEG-IFNalpha-2a was found to be more effective than CIFNalpha-2a, with viral load having no impact on treatment response.
View Article and Find Full Text PDF

Objective: To investigate the HCV genotypes distribution in northern and southern cities in China and the difference between patients infected with HCV by transfusion and non-transfusion routes.

Methods: The HCV genotypes of the patients with chronic hepatitis C from 9 cities belonging to different regions were genotyped by the PCR products of 5 prime untranslated region NTR digested with restriction endonucleases, and the HCV genotypes distribution among different cities or between the patients infected with HCV through transfusion and other routes was analyzed.

Results: The HCV genotypes of 214 in 219 cases were determined; 197 patients were infected with monogenotype HCV.

View Article and Find Full Text PDF
[Studies on IgG antibodies of SARS patients].

Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi

March 2004

Objective: To investigate the significance of detecting specific serum IgG antibodies in clinical diagnosis of SARS as well as affecting factors.

Methods: Enzyme-linked immunoassay kit for SARS coronavirus antibodies developed by HuaDa Biological Company was applied to detect specific serum IgG from SARS patients and the production of SARS specific antibodies among patients of different age groups, sex and with or without steroid treatment were statistically compared.

Results: Out of 121 patients studied, 71.

View Article and Find Full Text PDF