Publications by authors named "Wei-nan Xu"
Article Synopsis
- Flammulina filiformis is a commercially important edible mushroom with medicinal properties, but the details of its biosynthesis at the molecular level are not well understood.* -
- The study sequenced the genome of a wild strain and found 10,396 gene models, including multiple biosynthetic gene clusters for terpenoids and polysaccharides, with differences in gene expression between wild and cultivated strains.* -
- The results showed that the wild strain has more genes related to terpenoid synthesis, with higher levels of expression in certain developmental stages, shedding light on the biology of F. filiformis and its potential uses.*
Objective: To observe the effect of moxibustion on cardiac function and expression of myocardial tumor suppressor protein p53, mammalian target of rapamycin (mTOR) and phosphorylated(p)-mTOR (excessive autophagy-associated proteins of cardiomyocytes) in rats with chronic heart failure (CHF), so as to explore its mechanisms underlying improvement of CHF.
Methods: SD rats were divided into blank control (＝11), model(＝8), autophagy activator (＝8), autophagy inhibitor (＝9) and moxibustion(＝9) groups. The CHF model was established by i．p.
NADPH oxidases are enzymes that have been reported to generate reactive oxygen species (ROS) in animals, plants and many multicellular fungi in response to environmental stresses. Six genes of the NADPH oxidase complex components, including vvnoxa, vvnoxb, vvnoxr, vvbema, vvrac1 and vvcdc24, were identified based on the complete genomic sequence of the edible fungus Volvariella volvacea. The number of vvnoxa, vvrac1, vvbema and vvcdc24 transcripts fluctuated with ageing, and the gene expression patterns of vvnoxa, vvrac1 and vvbema were significantly positively correlated.
View Article and Find Full Text PDF[Analysis of the academic features of the moxibustion of ' physicians].
Zhongguo Zhen Jiu
February 2019
' acupuncture and moxibustion physicians have a lot of talented people. Their academic theories promote the development of moxibustion theory. - used acupuncture and moxibustion together in clinic, and emphasized reinforcing and reducing method.
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- Lnc-IL7R is a long non-coding RNA that plays a crucial role in regulating inflammation and has been investigated for its potential as a biomarker in acute respiratory distress syndrome (ARDS).
- The study involved comparing plasma levels of lnc-IL7R in 85 ARDS patients and 49 healthy controls, revealing that lnc-IL7R levels were significantly lower in ARDS patients, particularly in severe cases, and correlated with disease severity.
- The findings suggest that lnc-IL7R could serve as a reliable biomarker for diagnosing ARDS and predicting the 28-day mortality rate among affected individuals.
A recent multi-center case-control study identified several single nucleotide polymorphisms (SNPs) within the cytokine-inducible SRC homology 2 domain (CISH) gene that are associated with susceptibility to tuberculosis (TB) in both African and Asian populations. To acquire a more robust and well-powered estimate of the putative influence of these SNPs on TB susceptibility, we conducted a well-designed case-control study in the Chinese Han population. We genotyped 3 previously identified SNPs within CISH in 600 patients with pulmonary TB and 618 healthy controls, and we calculated the pooled P-values and ORs of several studies that have also been conducted in the Chinese populations.
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