Publications by authors named "Wei-ming Lu"
Article Synopsis
- The study investigates in-gap states (IGSs) in perovskite oxide heterojunction films and their importance in forming and influencing interfacial two-dimensional electron gas (2DEG).
- It finds that IGSs can trap electrons, hindering charge transfer between the film and the interface, which can lead to insulating behavior at the interface.
- An ion trapping model is proposed to explain both the IGS phenomenon and experimental results like the unexpected detection of 2DEG at a normally insulating interface, along with the effects of substitution layers on 2DEG formation.
Objective: The monocyte chemoattractant protein-1 (MCP-1) -A2518G gene polymorphism has been found to be involved in the susceptibility to inflammatory bowel disease (IBD); however, the results of existing studies are controversial. The aim of this meta-analysis was to assess the relationship between the MCP-1 -A2518G polymorphism and the risk of IBD.
Methods: PubMed, EMBASE and MEDLINE were searched for studies assessing the relationship between the -A2518G polymorphism in MCP-1 gene and the risk of IBD.
[Fabrication of tissue engineered vein containing valve scaffolds].
Zhonghua Yi Xue Za Zhi
April 2012
Objective: To fabricate porous biodegradable tissue engineered vein containing valve scaffolds.
Methods: Based on the self-made cast, the tissue engineered vein containing valve scaffolds was fabricated by injection molding plus thermally induced phase separation. Poly (lactic-co-glycolic acid) (PLGA, LA/GA mole ratio 75:25) was used as matrices.
Background: Vascular anomalies are common and multidisciplinary involved diseases. The greatest impediment to their treatment in the past was their confusing terminology and clinical heterogeneities. This hospital-based retrospective study assessed some clinical characteristics, diagnosis, therapies and outcomes of patients with vascular anomalies in southeast China.
View Article and Find Full Text PDF[Risk factors and therapeutic strategies of deep venous thrombosis during pregnancy].
Zhonghua Yi Xue Za Zhi
November 2010
Objective: To summarize the epidemiology and risk factors of deep venous thrombosis (DVT) during pregnancy and develop therapeutic strategies.
Methods: Twenty-nine pregnant women with DVT were admitted into our hospital between 1991 and 2010. And their clinical data were retrospectively reviewed.
[Risk factors and therapeutic management of deep venous thrombosis in hospitalized children].
Zhonghua Yi Xue Za Zhi
April 2010
Objective: The incidence and treatment regimen for deep venous thrombosis (DVT) in hospitalized children in China are rarely reported. This report was to assess the incidence, risk factors and treatment strategy for deep venous thrombosis (DVT) among hospitalized children admitted to the First Affiliated Hospital, Sun Yat-sen University, a single tertiary-care hospital.
Methods: In twenty years between 1989 and 2009, 12 DVTs in hospitalized children (< 17 years old) were identified in this hospital.
To assess the effect of intensive statins therapy on the outcome of small-diameter vascular prosthesis, we investigated whether atorvastatin treatment (30 mg/d) could accelerate the re-endothelialization process and improve the patency rate in a canine infrarenal abdominal aorta-expanded polytetrafluoroethylene (ePTFE) bypass model. Furthermore, we also evaluated the effect of atorvastatin on the migratory and adherent capacity of circulating endothelial progenitor cells (EPCs) in vitro. Improved patency was confirmed by Doppler sonography and arteriography.
View Article and Find Full Text PDFObjective: To evaluate the effect of preoperative embolization of the feeding vessels of carotid body tumor in the treatment thereof.
Methods: 33 patients with carotid body tumors not less than 3 cm in diameter were examined by color Doppler ultrasound. Polyvinyl alcohol particle 250-1000 microm in diameter were suspended in meglumine diatrizoate or Ultravist and then injected via microcatheter into the feeding vessels until detainment or reflux was seen.
Background: Our objective was to identify the effects of MCP-1 siRNA in vivo transfection in an atherosclerosis model on local expression of MCP-1 and pathogenesis of atherosclerosis.
Methods: Carotid atherosclerosis was induced in 28 New Zealand white rabbits. Rabbits were divided into three groups randomly: RNAi group, model group, and blank plasmid group.
Objective: To observe the effect of L-arginine on diabetic rats.
Methods: Forty adult male Lewis rats were randomized equally into diabetic and normal control groups, and the former rats were treated intraperitoneally with streptozotocin to induce diabetes mellitus. Seven days later, half of the diabetic and normal rats were injected intraperitoneally with L-arginine at the daily dose of 1 g/kg, while the remainder were given saline instead.
[Effect of interleukin-8 in cell invasion and proliferation of human breast cancer].
Zhonghua Wai Ke Za Zhi
December 2005
Objective: To identify the effect of interleukin-8 in cell progression and invasion of human breast cancer.
Methods: Human cytokine antibody arrays were applied to screen a panel of cytokine expression from 11 human breast cancer cell lines, and the mechanism of identified key factors involved in breast cancer progression was studied.
Results: Profiling of cytokine expression showed the expression of interleukin-8 was related to estrogen receptor status, metastasis and vimentin status in the 11 human breast cancer cell lines.