Publications by authors named "Wei-ling Xiao"

Article Synopsis
  • - Myocardial infarction is a serious health issue caused by a blockage in the coronary arteries, leading to reduced blood flow and damage to the heart muscle.
  • - Current treatments aim to lower the heart's oxygen needs and relieve symptoms, but achieving effective results has been challenging.
  • - Research shows that using mesenchymal stem cells (MSCs) to treat myocardial infarction is both safe and effective, but there are ongoing debates about the best practices for their use, which need to be resolved for MSCs to become a standard treatment option.
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Aim: To analyze the effect of recombinant IL-1β on proliferation, migration, and the effect on IFNα induced cell growth inhibtion.

Methods: The vector pLIVE-mIL-1β was transfected into Hepa1-6 cells mediated by transIT-LT1. Gene expression level of IL-1β was analyzed by RT-PCR and Sandwich ELISA.

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Aim: To investigate the effect of the expression of recombinant IL-1beta in H22 hepatoma cells on its response to NK cell mediated cytotoxicity.

Methods: BALB/c mouse was stimulated by 6% of starch. Total RNA was prepared from peripheral blood monocytes (PBMCs).

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Aim: To investigate the inhibitory effect of IL-1beta antisense RNA on the sensitivity of HepG2 cells to the NK cell mediated cytotoxicity.

Methods: Two gene segments of IL-1beta [IL-1beta1(17-331, 315 bp) and IL-1beta2(246-505, 260 bp)] were selected for antisense RNA. Total RNA was extracted from PBMC of a healthy donor treated with LPS.

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