[Analysis of influencing factors of early femoral head necrosis after femoral neck fracture and construction of nomogram prediction model].

Objective: To explore the risk factors of early femoral head necrosis in patients with femoral neck fracture after operation, and to establish a nomogram prediction model.

Methods: A total of 167 patients with femoral neck fracture from January 2020 to April 2022 were selected and divided into necrosis group and non-necrosis group according to whether femoral head necrosis occurred in the early postoperative period. There were 21 males and 17 females in the necrosis group, aged from 33 to 72 years old, with an average of (53.

Preoperative prediction of axillary lymph node metastasis in patients with breast cancer based on radiomics of gray-scale ultrasonography.

Background: To investigate the performance of a radiomics model based on gray-scale ultrasonography (US) for the preoperative non-invasive prediction of ipsilateral axillary lymph node (ALN) metastasis in patients with breast cancer (BC).

Methods: A total of 192 pathologically confirmed BC patients were included in this study. The training set was comprised of 132 patients from hospital 1 and the test set was comprised of 60 patients from hospital 2.

NeoPeptide: an immunoinformatic database of T-cell-defined neoantigens.

Therapeutic vaccines represent a promising immunotherapeutic modality against cancer. Discovery and validation of antigens is the key to develop effective anti-cancer vaccines. Neoantigens, arising from somatic mutations in individual cancers, are considered as ideal cancer vaccine targets because of their immunogenicity and lack of expression in normal tissues.

The value of virtual touch tissue imaging quantification in the differential diagnosis between benign and malignant breast lesions.

Purpose: To evaluate the value and diagnostic performance of virtual touch tissue imaging quantification (VTIQ) and to determine the optimum cut-off value for differential diagnosis between benign and malignant breast lesions.

Methods: Conventional ultrasonography (US) and VTIQ were performed in 454 patients with 466 breast lesions with a Siemens Acuson S3000 ultrasound machine. All lesions were assessed by an ultrasound Breast Imaging Reporting and Data System (BI-RADS) and confirmed by histopathology.

Effects of ZJ0273 on barley and growth recovery of herbicide-stressed seedlings through application of branched-chain amino acids.

In this study, we evaluated the effect of the herbicide propyl 4-(2-(4,6-dimethoxypyrimidin-2-yloxy)benzylamino) benzoate (ZJ0273) on barley growth and explored the potential to trigger growth recovery through the application of branched-chain amino acids (BCAAs). Barley plants were foliar-sprayed with various concentrations of ZJ0273 (100, 500, or 1000 mg/L) at the four-leaf stage. Increasing either the herbicide concentration or measurement time after herbicide treatment significantly impaired plant morphological parameters such as plant height and biomass, and affected physiological indexes, i.

Size-independent neural networks based first-principles method for accurate prediction of heat of formation of fuels.

Neural network-based first-principles method for predicting heat of formation (HOF) was previously demonstrated to be able to achieve chemical accuracy in a broad spectrum of target molecules [L. H. Hu et al.

Can Molecular Quantum Interference Effect Transistors Survive Vibration?

Quantum interference in cross-conjugated molecules can be utilized to construct molecular quantum interference effect transistors. However, whether its application can be achieved depends on the survivability of the quantum interference under real conditions such as nuclear vibration. We use two simulation methods to investigate the effects of nuclear vibration on quantum interference in a meta-linked benzene system.

[Prediction and Identification of HLA-A*0201 Restricted CTL Epitopes from Eps8].

Objective: To find and identify HLA-A*0201 restricted cytotoxic T lymphocyte (CTL) epitopes from epidermal growth factor pathway substrate number 8 (Eps8) for specific immunotherapy based on Eps8-derived epitopes in clinic.

Methods: Online biological softwares involved C-proteasomal cleavage, MHC class I binding affinity and TAP transport efficiency were used for prediction of HLA-A*0201 restricted epitopes from Eps8. Then, T2-binding assays and peptide/MHC complex stability tests were used to further verify the predicted epitopes.

[Effect of irregular bedrock topography on the soil profile pattern of water content in a Karst hillslope.].

Based on three manually excavated trenches (projection length of 21 m, width of 1 m) along a typical Karst hillslope, the changing trends for soil-bedrock structure, average water content of soil profile and soil-bedrock interface water content along each individual trench were studied. The effect of irregular bedrock topography on soil moisture distribution was discussed. The results showed that the surface topography was inconsistent with the bedrock topography in the Karst hill-slopes.

[High resolution melting analysis for detecting of JAK2V617F mutation in patients with myeloproliferative neoplasms].

This study was purposed to investigate the feasibility of high resolution melting (HRM) in the detection of JAK2V617F mutation in patients with myeloproliferative neoplasm (MPN). The 29 marrow samples randomly selected from patients with clinically diagnosed MPN from January 2008 to January 2011 were detected by HRM method. The results of HRM analysis were compared with that detected by allele specific polymerase chain reaction (AS-PCR) and DNA direct sequencing.

[Diagnostic values of breast imaging and reporting data system and ultrasonic elastography for benign and malignant breast lesions].

Objective: To explore the diagnostic values of breast imaging and reporting data system (BI-RADS) and ultrasonic elastography (UE) for benign and malignant breast lesions.

Methods: A total of 122 breast lesions were studied with BI-RADS and UE scoring to compare the sensitivity and specificity according to the pathologic results. Receiver operating characteristic (ROC) curves were used to assess the diagnostic value of BI-RADS, UE and combination.

[Desorption characteristics of phosphorus in tea tree rhizosphere soil].

In order to explore the phosphorus (P) release process and its supply mechanism in tea tree rhizosphere soil, an exogenous P adsorption and culture experiment was conducted to study the P desorption process and characters in the tea tree rhizosphere soils having been cultivated for different years and derived from different parent materials. The least squares method was used to fit the isotherms of P desorption kinetics. There was an obvious difference in the P desorption process between the rhizosphere soils and non-rhizosphere soils.

[The application value of BI-RADS lexicon and high-frequency CDFI scoring in differentiation of benign from malignant lesions of the breast].

Objective: To explore the diagnostic value with BI-RADS lexicon and high-frequency color doppler ultrasonic scoring for breast diseases.

Methods: A total of 108 breast lesions were studied with BI-RADS lexicon and high-frequency color doppler ultrasonic scoring, and compared with pathologic results. Calculated the sensitivity, specificity, accuracy, positive predictive value, and negative predictive value.

A randomized controlled study on the effects of bisoprolol and atenolol on sympathetic nervous activity and central aortic pressure in patients with essential hypertension.

Objective: β-blockers (BBs) with different pharmacological properties may have heterogeneous effects on sympathetic nervous activity (SNA) and central aortic pressure (CAP), which are independent cardiovascular factors for hypertension. Hence, we analyzed the effects of bisoprolol and atenolol on SNA and CAP in hypertensive patients.

Methods: This was a prospective, randomized, controlled study in 109 never-treated hypertensive subjects randomized to bisoprolol (5 mg) or atenolol (50 mg) for 4-8 weeks.

[Advancement of peptide vaccines for hematologic malignancies].

Despite recent significant advances in the treatment of hematological malignancies, relapse of this disease is of great note with the existence of the minimal residual disease (MRD). Tumour peptide vaccine seems to be one of the effective immunotherapies for eliminating tumor cells of MRD. This review focuses on the late results of clinical trails of peptide vaccination protocols targeting WT1, RHAMM, BCR-ABL, PR1 in hematological malignancies and the development of specific immune responses to PRAME and Survivin peptides.

[Application of successive projections algorithm to nondestructive determination of total amino acids in oilseed rape leaves].

Near infrared (NIR) spectroscopy combined with successive projections algorithm (SPA) was investigated for the fast and nondestructive determination of total amino acids (TAA) in oilseed rape leaves. Total amino acids are important indices of the growing status of oilseed rape. A total of 150 leave samples were scanned, the calibration set was composed of 80 samples, the validation set was composed of 40 samples and the prediction set was composed of 30 samples.

Circulating endothelial progenitor cells in Chinese patients with acute stroke.

To test the hypothesis that a mobilization of endothelial progenitor cells (EPCs) occurs after acute cerebrovascular diseases, we evaluated the number of EPCs in the process of acute stroke. A total of 203 individuals were examined, including 100 patients with ischemic strokes, 36 patients with hemorrhagic strokes and 67 healthy controls. Ninety-eight patients were observed at days 1, 7, 14 and 28 after acute stroke.

[Content of soil heavy metals and characteristics of environmental quality in tea plantations of Changsha Baili Tea Zone].

The distributing and changing characteristics and content of soil heavy metals was studied using methods of field survey and sampling, indoor analysis, and pollution index were used to investigate the soil environmental quality in the tea plantations of Changsha Baili Tea Zone. The results showed that the content of soil total Pb, Hg, Cd, Cr, As, Ni basically was in the soil background value, their averages were 42.7, 0.

Imidacloprid susceptibility survey and selection risk assessment in field populations of Nilaparvata lugens (Homoptera: Delphacidae).

Imidacloprid has been used for many years to control planthopper Nilaparvata lugens (Stål) (Homoptera: Delphacidae) in China. To provide resistance assessment for the national insecticide resistance management program, we collected a total of 42 samples of the planthoppers from 27 locations covering eight provinces to monitor their dose responses and susceptibility changes to imidacloprid over an 11-yr period (1996-2006). Results showed that most field populations maintained susceptibility from 1996 to 2003 except for a population from Guilin, Guangxi, in 1997, which showed a low level of resistance to imidacloprid.

Survey of susceptibilities to monosultap, triazophos, fipronil, and abamectin in Chilo suppressalis (Lepidoptera: Crambidae).

To provide a foundation for national resistance management of the Asiatic rice borer, Chilo suppressalis (Walker) (Lepidoptera: Crambidae), a study was carried out to determine dose-response and susceptibility changes over a 5-yr period in the insect from representative rice, Oryza sativa L., production regions. In total, 11 populations were collected from 2002 to 2006 in seven rice-growing provinces in China, and they were used to examine their susceptibility levels to monosultap, triazophos, fipronil, and abamectin.

Comparison of dose responses and resistance ratios in four populations of the rice stem borer, Chilo suppressalis (Lepidoptera: Pyralidae), to 20 insecticides.

Background: Chemical control is a major strategy for suppressing the rice stem borer, Chilo suppressalis (Walker). Owing to their high toxicity and increasing resistance development in the target insect, many insecticides will be phased out entirely in 2007 in China. Alternatives with relatively low toxicity are urgently needed to replace traditional chemicals for rice stem borer control.

[Effects of fertilization on microbial biomass C and N in paddy soils derived from different parent materials].

Based on the monitoring of soil fertility, this paper studied the characteristics of microbial biomass C (MBC) and N (MBN) in paddy soils derived from different parent materials in Hunan Province. The results showed different fertilization systems had different effects on soil MBC and MBN. After 18 years fertilization, the MBC and MBN in different paddy soils had similar variation trend, with the sequence of paddy soil derived from lake sediment > from river alluvium and quaternary red earth > from limestone > from shale.

[Clinical study on the correlation between high sensitivity C-reactive protein and risk factors in cerebral vessel [corrected] disease].

Objective: To investigate correlation between high sensitivity C-reactive protein (hs-CRP) and risk factors of acute stroke and cerebrovascular disease.

Methods: Hs-CRP levels were determined in 118 hypertensive patients with acute stroke (86 patients with cerebral infarction and 32 patients with cerebral hemorrhage) and in 67 healthy volunteers as normal control group by scattered radiation immunoturbidimetry. The difference in hs-CRP was analyzed in these two groups, and the correlation between hs-CRP and the cerebrovascular disease risk factors were analyzed.