Serum advanced glycation end products are associated with insulin resistance in male nondiabetic patients with obstructive sleep apnea.

Purpose: Advanced glycation end products (AGEs) play an important role in the pathogenesis of diabetic vascular complications. Recently, growing evidence has shown that AGEs could be involved in the pathogenesis of insulin resistance. It has also been suggested that circulating AGE are associated with insulin resistance in nondiabetic patients.

The active alkaloids of Gelsemium elegans Benth. are potent anxiolytics.

Rationale: An increasing number of herbal products has been introduced to treat anxiety and depression. Gelsemium elegans Benth (G. elegans) is a well-known herbal plant in Asia.