Recyclable -Heterocyclic Carbene Porous Coordination Polymers with Two Distinct Metal Sites for Transformation of CO to Cyclic Carbonates.

Single-component catalysts with integrated multiple reactive centers could work in concert to achieve enhanced activity tailored for specific catalytic reactions, but they remain underdeveloped. Herein, we report the construction of heterogeneous bimetallic porous coordination polymers (PCPs) containing both porphyrin and -heterocyclic carbene (NHC) metal sites via the coordinative assembly of the NHC functionalities. Three heterobimetallic PCPs (, and ) have been prepared to verify this facile synthetic strategy for the first time.

Postsynthetic Modification of Half-Sandwich Ruthenium Complexes by Mechanochemical Synthesis.

A mild and environmentally friendly method to synthesize half-sandwich ruthenium complexes through the Wittig reaction between an aldehyde-tagged half-sandwich ruthenium complex and phosphorus ylide mechanochemically is reported herein. The mechanochemical synthesis of valuable half-sandwich ruthenium complexes resulted in a fast reaction, good yield with simple workup, and the avoidance of harsh reaction conditions and organic solvents. The synthesized half-sandwich ruthenium complexes exhibited high catalytic activity for transfer hydrogenation of ketones using 2-propanol as the hydrogen source and solvent.

Lipoprotein A, combined with alanine aminotransferase and aspartate aminotransferase, contributes to predicting the occurrence of NASH: a cross-sectional study.

Background: Nonalcoholic steatohepatitis (NASH) progresses from simple nonalcoholic fatty liver (NAFL) and has a poor prognosis. Abnormal lipid metabolism is closely related to the occurrence and development of nonalcoholic fatty liver disease (NAFLD). This study aimed to study the relationships between serum lipid metabolites and NASH, and to improve the early diagnosis of NASH.

A ruthenium bisoxazoline complex as a photoredox catalyst for nitro compound reduction under visible light.

An unreported ruthenium(ii) complex containing bisoxazoline ligands has been synthesized and characterized. To test the catalytic ability of the ruthenium complex, the synthesis of anilines from nitro compounds in the presence of a mild reducing agent sodium borohydride and visible light has been developed. Mechanistic studies involving the experiment and DFT calculations suggest that the reaction could involve a radical pathway with the assistance of a photoredox catalyst.

Coordination-driven self-assembly vs dynamic covalent chemistry: versatile methods for the synthesis of molecular metallarectangles.

Supramolecular coordination assemblies have a range of potential applications in chemical and biological sciences. Herein, simple modular methods for the synthesis of metallarectangles are described. The desired tetranuclear metallarectangles were synthesized by using coordination-driven self-assembly of half-sandwich rhodium-based organometallic clip units and organic ligands.

[Identification and preparation of a glycol-protein fraction AN from tea extracts and its and anti-hyperglycosemia activity].

The present study compared active ingredients of tea from different sources to select tea type and the fraction of tea extracts for the highest anti-hyperglycemic activity, and to verify anti-hyperglycemic activity of the selected tea extract. Tea extracts were separated and enriched by molecular weight using ultra-filtration technology. The extracts were first screened by -glucosidase inhibition assay, followed by using a rat inverted intestine sac system to measure the effect on glucose transport.

Half-sandwich cycloruthenated complexes from aryloxazolines: synthesis, structures, and catalytic activities.

Seven half-sandwich cycloruthenated complexes [Ru(p-cymene)LCl] (2a-2g) (L = 2-phenyl-2-oxazoline (2a), 2-p-tolyl-4,5-dihydrooxazole (2b), 4,4-dimethyl-2-phenyl-2-oxazoline (2c), 2-(4-chlorophenyl)-4,5-dihydrooxazole (2d), 2-(4-bromophenyl)-4,5-dihydrooxazole (2e), 2-(4-fluorophenyl)-4,5-dihydrooxazole (2f) and 2-(4-nitrophenyl)-4,5-dihydrooxazole (2g)) were synthesized and characterized. All half-sandwich cycloruthenated complexes were fully characterized by (1)H and (13)C NMR spectra, elemental analyses and infrared spectroscopy. The molecular structures of 2a, 2d and 2e were confirmed by single-crystal X-ray diffraction methods.

Crystal structure of 3,3'-diisopropyl-1,1'-(pyridine-2,6-di-yl)bis-[1H-imidazole-2(3H)-thione].

In the title compound, C17H21N5S2, the dihedral angles between the central pyridine ring and its pendant imidazole rings are 29.40 (9) and 40.77 (9)°; the pendant rings are twisted in an opposite sense with respect to the central ring.

Six Zn(II) and Cd(II) coordination polymers assembled from a similar binuclear building unit: tunable structures and luminescence properties.

Six Zn(ii) and Cd(ii) coordination polymers were constructed by treating a 2-substituted 8-hydroxyquinolinate ligand containing a pyridyl group with zinc or cadmium salts, and characterized by a variety of techniques. Interestingly, based on a similar binuclear Zn(ii) or Cd(ii) building unit, the supramolecular structures of the six coordination polymers () exhibit an unprecedented structural diversification due to the different choices of metal salts. and represent a novel 2D framework containing 1D infinite right- and left-handed helical chains.

Synthesis and characterization of bisoxazolines- and pybox-copper(II) complexes and their application in the coupling of α-carbonyls with functionalized amines.

Binuclear complexes [{(DMOX)CuCl}2(μ-Cl)2] (1), mononuclear complexes [(DMOX)CuBr2] (2) (DMOX = 4,5-dihydro-2-(4,5-dihydro-4,4-dimethyloxazol-2-yl)-4,4-dimethyloxazole) and the pybox Cu(II) complex [(Dm-Pybox)CuBr2] (3) (Dm-Pybox = 2,6-bis[4',4'-dimethyloxazolin-2'-yl]pyridine) were obtained by reactions of CuX2 (X = Cl, Br) with DMOX and Dm-Pybox ligands, respectively. The molecular structures of 1, 2 and 3 have been determined by single-crystal X-ray diffraction analyses. The complexes 2 and 3 are efficient in catalyzing α-amination of ketones and esters through α-bromo carbonyl intermediate.

Half-sandwich Ir-based neutral organometallic macrocycles containing pyridine-4-thiolato ligands.

Neutral organometallic cyclic tri- and tetra-nuclear half-sandwich iridium complexes and , connected with pyridine-4-thiolato ligands, were synthesized and characterized by X-ray crystallography.

Syntheses and structures of half-sandwich iridium(III) and rhodium(III) complexes with organochalcogen (S, Se) ligands bearing N-methylimidazole and their use as catalysts for norbornene polymerization.

The organochalcogen ligands derived from 3-methyl-imidazole-2-thione/selone groups, Mbit, Mbis, Ebit and Ebis [Mbit = 1,1'-methylenebis(3-methyl-imidazole-2-thione); Mbis = 1,1'-methylenebis(3-methyl-imidazole-2-selone), Ebit = 1,1'-(1,2-ethanediyl)bis(3-methyl-imidazole-2-thione), Ebis = 1,1'-(1,2-ethanediyl)bis(3-methyl-imidazole-2-selone)] have been synthesized and characterized. Reactions of [Cp*Ir(micro-Cl)Cl]2 and [Cp*Rh(micro-Cl)Cl]2 (Cp* = eta5-pentamethylcyclopentadienyl) with Mbit, Mbis, Ebit and Ebis result in the formation of the complexes [Cp*Ir(Mbit)Cl]Cl 1a x Cl), [Cp*Ir(Mbis)Cl]Cl (3a x Cl), [Cp*Ir(Ebit)Cl]Cl (1b x Cl), [Cp*Ir(Ebis)Cl]Cl (2a x Cl), [Cp*Rh(Mbit)Cl]Cl (2b x Cl), Cp*Rh(Mbis)Cl][Cp*RhCl(3)] (3b x[Cp*RhCl(3)]), [Cp*Rh(Ebit)Cl]Cl (4a x Cl) and [Cp*Rh(Ebis)Cl]Cl (4b x Cl), respectively. All compounds have been characterized by elemental analysis, NMR and IR spectra.

Template-controlled topochemical photodimerization based on "organometallic macrocycles" through single-crystal to single-crystal transformation.

Organometallic macrocycles and undergo [2+2] photochemical cycloaddition to form and in quantitative yield, accompanied by a single-crystal to single-crystal transformation.

[The feasibility exploration of cultured newborn rat ventricular myocyte taking the place of acutely enzymatic isolated myocardium for study in electrophysiology of pacemaker current].

Objective: To investigate the feasibility of cultured rat ventricular myocytes taking the place of acutely enzymatic isolated myocardia for study in the pacemaker current electrophysiology.

Methods: By using patch-clamp technique, the whole-cell pacemaker currents were recorded to study the difference of pacemaker current electrophysiology between neonatal rat ventricular myocytes isolated acutely and maintained in cell culture.

Results: The cell membrane capacitances (Cm) were significantly decreased in myocardia even upon short term of cell culture.