Publications by authors named "Wei-cheng Deng"

Advanced schistosomiasis, encompassing a wide range of pathologic entities and multi-complications, poses a serious threat on the patients' health. Through comprehensive analysis and evaluation on related aspects regarding clinical classification, main methods of auxiliary examination and treatment (including types of surgical procedure) of advanced schistosomiasis, we think that the individual based multidisciplinary comprehensive treatment according to varying conditions of patients is the most optimal treatment mode of advanced schistosomiasis. It is further proposed that multidisciplinary collaborative diagnosis and treatment system should be undoubtedly established, multidisciplinary case discussions be regularly organized, and treatment expert teams be stably formed, in order to significantly improve the level of diagnosis and treatment of advanced schistosomiasis, so as to reduce the misdiagnosis and improve the therapeutic effect in advanced schistosomiasis control.

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Advanced schistosomiasis is the most serious clinical type of schistosomiasis. Its diagnosis and treatment are related to many special departments, such as gastroenterology, general surgery, neurology, endocrinology, radiology, traditional Chinese medicine, blood purification, endoscopy, intervention, and ICU. It is necessary to apply a multidisciplinary treatment (MDT) mode.

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Article Synopsis
  • The Chinese government's medical assistance program for advanced schistosomiasis patients, initiated in Hunan Province ten years ago, has developed effective management practices and technologies.
  • The author conducted a retrospective study of the program's impact from 2006 to 2015, finding it to have a high therapeutic success rate and strong patient and societal satisfaction.
  • The paper aims to share insights and strategies to improve the management of this medical assistance program with professionals in other provinces, while also addressing current challenges.
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This paper summarizes the clinical diagnosis and treatment of imported African schistosomiasis, in order to make the therapeutic standards. Imported African schistosomiasis includes mainly schistosomiasis haematobia and schistosomiasis mansoni in China. In order to set up the operational standards, enhance diagnostic and cure rates, and reduce the complications, we review the related literature combined with our experience over years, and summarize, in this paper, the pathogenic mechanism, and key points of clinical diagnosis and treatment of schistosomiasis haematobia and schistosomiasis mansoni, so as to provide the reference for clinical doctors.

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Objective: To understand the direct medical expense for surgical patients with splenomegalic advanced schistosomiasis and its influencing factors, so as to provide evidences for relevant departments to improve the rescue strategy of advanced schistosomiasis.

Methods: The data about the expenses of patients with splenomegalic advanced schistosomiasis hospitalized in Xiangyue Hospital affiliated to Hunan Institute of Schistosomiasis Control from January 2010 to August 2014 were collected, the hospitalization expense and hospital stays of the patients were analyzed, and the factors influencing the hospital expenses were analyzed by the univariate and multi-factor analyses.

Results: From January 2010 to August 2014, totally 249 cases were hospitalized in the hospital, their average hospital stays and hospital expenses were 28.

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In order to further standardize the diagnosis and treatment of schistosomiasis japonica in China, on the basis of evidence-based medicine, the experts on schistosomiasis control from Hunan, Hubei and Jiangxi provinces summarized their consensuses on the disease after the discussion on the current situation and progress of clinical diagnosis and treatment of schistosomiasis in China, with the reference to the Diagnostic Criteria for Schistosomiasis (WS261-2006), which aimed to establish the therapeutic standards or guideline of schistosomiasis in China.

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Objective: To explore a surgical treatment of advanced schistosomiasis with cavernous transformation of the portal vein.

Method: The clinical data of 18 patients who suffered from advanced schistosomiasis with cavernous transformation of the portal vein were collected and analyzed retrospectively in the Affiliated Xiangyue Hospital of Hunan Institute of Parasitic Diseases.

Results: Two cases were undertaken the endoscopic variceal ligation, and the upper gastrointestinal bleeding happened 32 months and 40 months after the treatment respectively, and they received the splenectomy and esophagogastric devascularization again; 16 cases were undertaken the splenectomy and esophagogastric devascularization.

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Objective: To assess the efficiency of multi-disciplinary treatment (MDT) for advanced schistosomiasis.

Methods: A total of 173 advanced schistosomiasis patients who received MDT were selected from January 2010 to December 2011. These patients included 75 splenomegaly cases and 98 ascites cases.

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According to the long-term clinical experience on schistosomiasis control of Hunan Institute of Schistosomiasis and the latest clinical guidelines, this paper makes a discussion on the clinical pathways of 3 types of schistosomiasis, and establishes the pathway management including diagnosis, therapy, hospital stays, and treatment after discharge, nursing, recovery, follow-up and so on, aiming to formulate a standardized flow or a pathway for schistosomiasis treating.

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Objective: To recommend a new clinical classification of advanced schistosomiasis for improving the diagnosis and evaluation of therapeutic effect of advanced schistosomiasis.

Methods: The medical records of 11 092 cases of advanced schistosomiasis from the Xiang-Yue Hospital from January 1990 to January 2010 and the medical aid centre for advance schistosomiasis in Hunan Province from January 2004 to January 2010 were collected and classified with the current and new clinical classification methods and the results were statistically analyzed and compared.

Results: Based on the current classification method, there were huge splenomegaly (5 710 cases), ascites (2 993 cases), colon proliferative (834 cases), and dwarf (54 cases).

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