Publications by authors named "Wei-Yi Shi"

To inhibit eutrophication caused by endogenous pollutants release, the experiment explored the efficiency and mechanism of the synchronous control of nitrogen (N) and phosphorus (P) release from sediments in shallow lakes under wind disturbance by modified Ca/Al-based sludge (MS) and modified zeolite (MZ). High-temperature calcination and NaCl impregnation increased the pore volume of MS and Na content of MZ, and the adsorption capacity of MS for PO-P and MZ for NH-N was as high as 42.01 and 20.

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Article Synopsis
  • - KRAS mutations lead to aggressive tumors and drug resistance in colorectal cancer, making treatment difficult, particularly with targeted therapies like regorafenib.
  • - TRIM21, influenced by ERK2 and KRAS signaling, plays a key role in regulating c-Myc, which affects glycolysis and contributes to resistance to regorafenib.
  • - Targeting TRIM21 to inhibit its phosphorylation may improve treatments for KRAS-mutant colorectal cancer, with the antidepressant vilazodone showing promise in enhancing the effectiveness of regorafenib in research models.
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A composite wetland (CECW) was constructed by introducing P-adsorption filler (EPAF) and activated sludge into traditional wetlands for treating actual sewage. The results showed that EPAF improved P removal through physico-chemical adsorption, and it could be stably regenerated after adsorption saturation without potential risks. Meanwhile, zeolite promoted NH-N reduction in sewage by cation exchange.

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To explore the appropriate controlled ovarian hyperstimulation (COH) protocols in infertility patients who received the fertilization (IVF)/intracytoplasmic sperm injection (ICSI) treatments during the COVID-19 pandemic. This retrospective cohort study evaluated the efficiency of the early follicular-phase long-acting GnRH-agonist long (EFLL) protocol (a new protocol developed by Chinese clinicians), prolonged pituitary down-regulation of EFLL protocol (Pro-EFLL), and the GnRH-ant protocol for couples meeting the study criteria between February 2020 and June 2020 who were treated by the First Affiliated Hospital of Zhengzhou University during the COVID-19 pandemic, and compared the pregnancy rates and miscarriage rates per fresh transfer cycle, number of retrieved oocytes, endometrial thickness on the day of hCG injection and the number of fertilized oocytes, mature oocytes, fertilized oocytes, and transferable embryos among the three protocols. We found that the prolonged pituitary down-regulation during the COVID-19 pandemic by utilizing a full-dose of GnRH-a administrated in infertility patients were no differences in clinical outcomes than other protocols, The prolonged pituitary down-regulation protocol and EFLL protocol were associated with a higher Endometrial thickness on the day of hCG injection (12.

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The robot-assisted insertion surgery plays a crucial role in biopsy and therapy. This study focuses on determining the optimum puncture pattern for robot-assisted insertion, aiming at the matching problem of needle insertion parameters, thereby to reduce the pain for patients and to improve the reachability to the lesion point. First, a 6-degrees of freedom (DOFs) Computed Tomography (CT)-guided surgical robotic system for minimally invasive percutaneous lung is developed and used to perform puncture experiments.

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Background: Robot-assisted puncture has gradually attracted more attention and practical clinical application. The lesion positioning and the needle positioning are the basis to ensure the accuracy of puncture and the key techniques in insertion operation.

Methods: A lesion positioning method is established which is realized only by the robot-CT system without using external positioning system, and an omnidirectional needle positioning method is also developed and realized by using VRCM, in order to make the puncture needle always keep pointing to the lesion point.

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