Publications by authors named "Wei-Xuan Chen"

Article Synopsis
  • This study reports on the initial experience of one-stage flexible ureteroscopic lithotripsy (FURL) using specific ureteral access sheaths and digital flexible ureteroscopes for treating upper ureteral and renal stones in 900 adult patients.
  • The results show that the procedure was successful for the majority, with a stone-free rate of nearly 90% one month post-surgery, while only a small percentage experienced complications like fever or pain.
  • The study concludes that FURL is a practical, safe, and effective treatment option for most adults with upper urinary tract stones, without the need for stenting prior to the procedure.
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Depression is increasingly recognized as an inflammatory disease, with inflammatory crosstalk in the brain contributing its pathogenesis. Life stresses may up-regulate inflammatory processes and promote depression. Although cytokines are central to stress-related immune responses, their contribution to stress-induced depression remains unclear.

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Objective: To understand the epidemiological characteristics of malaria in Wuxi City, and explore effective strategies and measures for malaria elimination.

Methods: The data on malaria cases in Wuxi from 2005 to 2014 were collected and analyzed.

Results: In Wuxi City, from 2005 to 2014, 201 malaria cases were reported, of which, there were 52 local cases and 149 imported cases.

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Objective: To understand the capability of parasitic disease control and prevention among professional and technical personnel in medical and health institutions in Wuxi City, so as to provide the evidence for promoting relative capability building.

Methods: Forty-one professional and technical persons from 22 medical and health institutions received the evaluation through the theoretical knowledge exam and laboratory operation skill assessment.

Results: The average score of theoretical knowledge exam was (76.

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Objective: To provide the scientific evidence for expansion of medicinal parts of Zanthoxylum nitidum by comparing the effects of anti-contusion injury, analgesia and anti-inflammation of its root and stem.

Methods: The pharmacological effects between root and stem of Zanthoxylum nitidum were compared by observing the anti-injury effect in rats with injury struck by hammer. The analgesic effect in mice was evaluated by writhing test and hot plate test, and the anti-inflammatory effect on paw edema induced by carrageenan and granuloma induced by cotton pellet were investigated in rats.

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Objective: To provide the experimental evidence for expansion of medicinal parts of Zanthoxylum nitidum by comparing the effects of anti-gastritis,gastric mucosal protection and gastrointestinal movement promotion of its root and stem.

Methods: The pharmacological effects between root and stem of Zanthoxylum nitidum were compared by observing the anti-gastritis effect on rats with chronic superficial gastritis induced by iodoacetamide, evaluating the gastric mucosal protective effect on rats’ gastric ulcer induced by stress, indometacin and pylorus ligation test, and investigating gastrointestinal movement promotion effect on mice gastric evacuation and intestinal propelling.

Results: Both root and stem of Zanthoxylum nitidum showed effects of relieving the inflammation symptoms of rats’ gastric mucosa induced by iodoacetamide, gastric ulcer respectively induced by stress, and presenting a strong inhibition of free acid and pepsin activity in gastric juice.

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Objective: To establish the HPLC fingerprint chromatograms of crude Notoginseng, cell wall-broken powder and cell wall-broken decoction pieces of Notoginseng and provide evidence for quality control of cell wall-broken decoction pieces of Notoginseng.

Methods: The HPLC procedure was performed on the chromatographic column of Hypersil ODS2, and the mobile phase was acetonitrile and water in gradient elution with the flow velocity of 1.0 mL/min.

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