Publications by authors named "Wei-Sheng Jiang"

Article Synopsis
  • The study aimed to analyze the changes in intestinal parasitic diseases in Jiangxi Province from 1989 to 2014 to inform prevention strategies.
  • Data was collected from national surveys in 1989 and 2014, revealing an 87.89% decline in the prevalence of human intestinal parasites, from 79.59% to 9.64%.
  • The findings showed that while the number of parasite species decreased, soil-transmitted nematodes remained the most common parasites, with higher prevalence rates in females across all age groups.
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Soil transmitted helminths (STHs) burden was enormous in China several decades ago, however, rigorous control efforts have been successful with appreciable reduction in diseases burden. Here, we assessed provincial-level data derived from cross sectional surveys, executed in 1989, 2002 and 2014, on the prevalence of STHs among populations in Jiangxi province, China. This study, also, reported STHs integrated control intervention aimed at reducing STHs transmission and worm burden among population at county-level.

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Article Synopsis
  • * A 2016 survey revealed that 19.51% of residents eat raw freshwater fish, with infection rates varying by age and correlating positively with this eating behavior.
  • * Only a small percentage (11.46%) of residents understood the health risks associated with raw-fish consumption, indicating a need for improved health education and changing dietary habits to effectively control clonorchiasis.
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  • - The study aimed to assess the infection status in children aged 3-6 years in Jiangxi Province in 2014, to help inform prevention and control measures for parasitic diseases.
  • - A survey involving 1,486 children found an overall infection rate of 13.73%, with variations based on age and income levels, peaking at 18.24% in 5-year-olds.
  • - The results indicate a significant infection problem among children in the province, prompting the need for ongoing monitoring and control efforts by health authorities.
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  • * Out of 21,615 participants, 1,095 were found to be infected, reflecting a prevalence of 5.07%, with the highest rates observed in Nanfeng County and among older females.
  • * Conclusions indicated a significant decline in hookworm infections, with high-risk groups identified as low-education individuals, females, and the elderly.
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Article Synopsis
  • A study was conducted to analyze soil-transmitted nematode infections in Jiangxi Province between 1989 and 2014, using data from three epidemiological surveys and stool examinations.
  • The results showed a dramatic decrease in overall infection rates by 91.89%, with significant reductions in various types of nematodes, although females generally had higher infection rates than males across different ages and ecological districts.
  • Despite the overall decline in infections, soil-transmitted nematodes remained the most common intestinal parasite, affecting mainly rural females and the elderly population.
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Objective: To understand the current prevalence of clonorchiasis in Jiangxi Province.

Methods: A survey was performed according to the scheme of the 3rd Principal Human Parasites of Jiangxi Province. Based on the ecological regions, a stratified cluster sampling method was applied by the economic and geographic situation.

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Objective: To understand the capability of parasitic disease diagnosis among professionals from the clinic laboratory of Class A tertiary hospitals in Jiangxi Province.

Methods: The teams that took part in the competition were formed from 20 Class A tertiary hospitals, with 2 contestants per team. The competition contents included written examination and skill operation.

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Objective: To understand and analyze the epidemic status of principal human parasites in Jiangxi Province, so as to provide the evidence for formulating The 13rd Five-Year Project of Parasites Control.

Methods: A survey was performed according to the scheme of The 3rd National Survey of Principal Human Parasites as well as the specific situation of Jiangxi Province. The survey of the soil-transmitted nematodes and intestinal protozoa were performed based on the ecological regions and stratified by economic and geographic situation.

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  • - The study aimed to find the best preservation conditions for schistosome eggs to improve quality control for hatching tests by observing the hatching rates and activity of the resulting miracidia over time.
  • - Schistosome eggs were collected from infected rabbits and preserved in various solutions at two temperatures (4 °C and 15 °C), with hatching rates monitored at 7-day intervals for up to 280 days.
  • - Results indicated that Mili-Q water at 4 °C was the most effective preservation method, maintaining a hatching rate below 10% for 196 days, while other solutions showed significantly lower viability much sooner.
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  • The study aimed to assess the characteristics of water contact among residents in Poyang Lake, where schistosomiasis is common, following the Three Gorges Project.
  • A survey revealed that 69.77% of residents had infested water contact, predominantly during spring, summer, and autumn, with activities like fishing and swimming contributing most to exposure.
  • The findings indicate a shift in exposure activities, with fishing becoming the main activity linked to infested water contacts, while traditional activities like farming are now less frequent.
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Objective: To develop a Schistosoma japonicum antibody test kit (IHA).

Methods: According to the requirement of Good Manufacturing Practice (GMP) and Quality Control (QC) of drugs, the components of kit as well as its preparation method and procedure were studied, and the test kit was assembled and its diagnostic effect was assessed.

Results: The sensitivity and specificity were up to 94.

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Article Synopsis
  • The study aims to assess the prevalence of soil-transmitted nematode infections among residents in Fusheng Village, Poyang Lake area, Jiangxi Province, based on stool samples collected in 2008.
  • The findings reveal a high overall infection rate of 37.97%, with notable variations: higher rates in females for Ascarid lumbricoides and hookworm, and age-related trends show increased infections with older age.
  • The conclusion emphasizes the need for effective control strategies, including health education, regular treatments, proper waste management, and environmental improvements to reduce transmission.
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Objective: To explore the relationship between fecal examinations and worm collection results in a community investigation of Ascaris lumbricoides infection.

Methods: A total of 1 019 residents in Zhangxi Village, Nanchang County, Jiangxi Province were investigated with the Kato-Katz technique and worm collection after deworming.

Results: Among 1 019 residents investigated, the actual prevalence of A.

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Objective: To evaluate the medium-term effect and stability of the schistosomiasis comprehensive control strategy based on infectious source control after its popularization and application in marshland endemic areas.

Methods: The schistosomiasis comprehensive control strategy based on infectious source control including "replacing buffalo with machine", "marshlands isolation and grazing forbidden", etc. was implemented in all villages of Sanli Township, a heavy endemic area with schistosomiasis in Jianxian County.

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Article Synopsis
  • * The study introduces a new method called the formalin-ethyl acetate sedimentation-digestion (FEA-SD) technique, designed to effectively isolate and identify S. japonicum eggs in the feces of infected water buffaloes, improving previous methods.
  • * By removing about 70% of the debris in fecal samples, the FEA-SD technique enhances visualization of the eggs under a microscope, making it a valuable surveillance tool for monitoring infection rates in animal populations, especially in areas where schistosomiasis control efforts are ongoing.
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Objective: To evaluate the effect of schistosomiasis control by forbidding livestock denaturing on marshland with Oncomelania snails and to analyse its influencing factors.

Methods: The village of Aiguo, Xinhe, Huangjia, Fanrong, Fengfu and Caomen and its respective nearby marshland, i.e.

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Objective: To study the impact of water level changes on the distribution of snails around lakes, and to study the possibility of forecasting the distribution of snails according to changes of water level reacted by remote sensing images.

Methods: All information including water level information of Xingzi Hydrometric Station from 1997 to 2007, twelve TM images of Poyang Lake between 1998 and 2006 were collected. The water areas of Poyang Lake was extracted by MNDWI threshold approach, and the relationships between water areas from TM images and water level from Hydrometric Station was analyzed; Majiawan and Menqiantan marshland of Zhuxi village, Xingzi county was chosen as study pilot to set frames and investigate snails 2991 frames in 2007, and the information of snails of this pilot from 1998 to 2006 was collected to analyze the relationships between snails and water level.

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Objective: To explore the diagnostic efficiency of circulating antigen using the TM5.28 mAB-biotin-avidin system for the detection of schistosomiasis japonica.

Methods: A mAb-biotin-avidin system was set up using a TM5.

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