Publications by authors named "Wei-Ru Jia"
AAPS PharmSciTech
June 2020
Article Synopsis
- The study explores how modifying the surface of curcumin-loaded PLGA nanoparticles using fungal hydrophobin can impact their effectiveness as drug carriers in cancer treatment.
- Results showed that the hydrophobin-coated nanoparticles had better cytotoxicity and cellular uptake in cancer cell lines compared to non-coated ones, while maintaining a similar drug release pattern.
- Despite increased antitumor efficacy of the hydrophobin-coated nanoparticles in mice, there was no significant difference in blood retention time compared to the uncoated nanoparticles, indicating the need for further research on tissue distribution.
