Publications by authors named "Wei-Ran Gen"
Article Synopsis
- This study investigates the effect of linagliptin, a drug that inhibits DPP-4, on heart recovery after being preserved in low temperatures for 9 hours.
- The research shows that adding linagliptin to the preservation solution significantly reduces cardiac dysfunction caused by hypothermia, by inhibiting oxidative stress markers and proteins related to mitochondrial fragmentation.
- Ultimately, linagliptin improves heart function recovery by preventing specific protein modifications that damage mitochondria, indicating its potential as a cardioprotective agent.
