Efficacy of long-term orthokeratology treatment in children with anisometropic myopia.

Aim: To explore the efficacy of the orthokeratology lens for anisometropic myopia progression.

Methods: A retrospective study was performed. Cycloplegic refraction and axial length (AL) were collected from 50 children (10.

MicroRNA-190b regulates lipid metabolism and insulin sensitivity by targeting IGF-1 and ADAMTS9 in non-alcoholic fatty liver disease.

Nonalcoholic fatty liver disease (NAFLD) is characterized by ectopic lipid accumulation and insulin resistance, yet the underlying molecular mechanisms are poorly understood. MiR-190b is thought to play a role in hepatocellular carcinoma by modulating insulin resistance; however, its role in NAFLD remains unknown. Here, we found that miR-190b expression was significantly increased in the liver tissues of patients with NAFLD, compared to normal tissues.

Evaluation of the safety and efficacy of therapeutic bandage contact lenses on post-cataract surgery patients.

Aim: To evaluate the safety of therapeutic bandage contact lens for post-cataract surgery patients and to illustrate its efficacy on post-operative comfort and tear-film stability.

Methods: A total of 40 participants were recruited and randomly divided into two groups. Group one was instructed to wear bandage contact lenses for a week and use antibiotic eye drops for a month since the first day after surgery.

Effect of infusion pressure during cataract surgery on ganglion cells measured using isolated-check visual evoked potential.

Aim: To detect the relationship between infusion pressure and postoperative ganglion cells function.

Methods: This prospective observational cohort study included sixty-one eyes that underwent uncomplicated cataract surgery. Patients were divided into two groups according to infusion time (IT) recorded using surgery equipment [Group A: IT>IT (27 eyes); Group B: IT View Article and Find Full Text PDF

TLR-4/miRNA-32-5p/FSTL1 signaling regulates mycobacterial survival and inflammatory responses in Mycobacterium tuberculosis-infected macrophages.

Macrophages play a pivotal role in host immune response against mycobacterial infection, which is tightly modulated by multiple factors, including microRNAs. The purpose of the present study was to investigate the biological function and potential mechanism of miR-32-5p in human macrophages during Mycobacterium tuberculosis (M.tb) infection.

[Randomly sampling survey of dry eye awareness in general eye clinic].

Objective: To determine the dry eye awareness in the populations visiting general eye clinic.

Methods: This was a cross-sectional study. A questionnaire about dry eye was designed and administrated to Peking University Third Hospital General Eye Clinic patients (n = 804) from June 2010 to June 2011.