Publications by authors named "Wei-Ping Xia"
Background: Kidney damage often develops into renal fibrosis. Apoptosis and inflammatory response are the main factors driving the process of renal fibrosis. Here we showed that lncRNA XIST/ miR-19b / SOX6 signal axis regulated apoptosis and inflammation of renal fibrosis.
View Article and Find Full Text PDFArticle Synopsis
- - Propofol, a common anesthetic, requires dosage adjustment based on aging, and researchers hypothesize that telomere length (TL) could help predict the appropriate dose needed, especially in elderly patients.
- - In a study involving 100 surgical patients, researchers analyzed the correlation between propofol dosage and factors such as TL, body weight, sex, and changes in the Bispectral Index (BIS) during anesthesia, finding a strong connection with TL (r = 0.78).
- - The study concluded that TL is a significant factor in predicting propofol dosage, which could enhance anesthesia safety and decrease complications, while mutations in the telomerase RNA component (TERC) were not detected. *
This study investigated the correlation between periprostatic fat thickness (PPFT) measured on magnetic resonance imaging and lower urinary tract symptoms, erectile function, and benign prostatic hyperplasia (BPH) progression. A total of 286 treatment-naive men diagnosed with BPH in our department between March 2017 and February 2019 were included. Patients were divided into two groups according to the median value of PPFT: high (PPFT >4.
View Article and Find Full Text PDFObjective: To establish a Wistar rat model of chronic abacterial prostatitis (CAP) by injecting purified prostate protein and Freund's complete adjuvant, and to study the influence on the morphology and proinflammatory expression.
Methods: Male rats were injected with the Pertussis-Diphteria-Tetanus vaccine into the abdominal cavity and purified prostate protein and Freund's complete adjuvant intradermally at 0 and 30 days. At 60 days, the rats were sacrificed, and then the prostate specimens were observed, under the light microscope and electron microscope, and the changes of proinflammatory expression was observed too, using PCR technique.
[Effect of immunological orchitis on sperm specific enzyme and fertility].
Zhonghua Nan Ke Xue
August 2003
Objective: To investigate the effect of immunological orchitis on spermatic specific enzyme and fertility.
Methods: Experimental allergic orchitis (EAO) model of guinea pigs was duplicated. The histological and morphological changes of spermatic acrosomal protease and hyaluronidase, lactate dehydrogenase, sperm in epididymis and testes were observed by means of enzyme kinetical spectrophotometry and gelatin fixation of substrate thin membrane.