Yanghe decoction alleviates osteoarthritis by AMPK-SIRT3 positive feedback loop-mediated Mitochondrial autophagy.

Ethnopharmacological Relevance: Yanghe Decoction(YHD) is a traditional Chinese medicine compound known for its efficacy in treating osteoarthritis (OA).

Aim Of The Study: We aimed to explore the underlying mechanisms of YHD in relation to OA.

Materials And Methods: UHPLC-MS technology was used to identify the material basis of YHD.

Shi-Style Cervical Mobilizations Versus Massage for Cervical Vertigo: A Multicenter, Randomized, Controlled Clinical Trial.

Large sample and high-quality evidence to evaluate the preliminary safety of the mobilizations and massage for cervical vertigo are not yet available. Thus, the present study aimed to investigate the comparative effectiveness and preliminary safety of Shi-style cervical mobilizations (SCM) compared with traditional massage (TM) in cervical vertigo patients. A prospective, multicenter, open-label, randomized, controlled clinical trial with a 1:1 allocation ratio.

Shi-style cervical manipulations for cervical radiculopathy: A multicenter randomized-controlled clinical trial.

Background: There is a lack of high-quality evidence supporting the use of manipulation therapy for patients with cervical radiculopathy (CR). This study aimed to evaluate the effectiveness of Shi-style cervical manipulations (SCMs) versus mechanical cervical traction (MCT) for CR.

Methods: This was a randomized, open-label, controlled trial carried out at 5 hospitals in patients with CR for at least 2 weeks and neck pain.