Background And Aims: An ulcerative colitis rat model was established with baicalin as the treatment.
Materials And Methods: Quantitative real-time polymerase chain reaction (QRT-PCR) and Western blot analysis were used to determine inflammatory factor expression in interstitial cells of Cajal.
Results: Baicalin treatment reduced the ulcerative colitis symptoms, such as bloody diarrhea, reduction in body weight, and vomiting.
Colorectal cancer is cancer of the colon or rectum and is the third most prevalent form of cancer. Currently, there are several shortcomings in the prognosis and early detection of colon cancer. The present study aims to address questions pertaining to the role of microRNA (miR)-137 in colon cancer progression and the mode of regulation.
View Article and Find Full Text PDFBACKGROUND Colorectal adenocarcinoma is the second leading cause of cancer-related death in the world. The stage of the disease is related to the survival of the patient, and in early phases surgery is the main modality of treatment. The main aim of modern medicinal chemistry is to synthesize small molecules via drug designing, especially by targeting tumor cells.
View Article and Find Full Text PDFWorld J Gastroenterol
December 2014
Gastric ulcer is a common disorder of the digestive system. Current therapeutic regimens largely rely on Western medicine. However, numerous studies have demonstrated that herbal medicines can effectively treat gastric ulcer in humans and various animal models via divergent mechanisms.
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