Screw trajectory affects screw cut-out risk after fixation for nondisplaced femoral neck fracture in elderly patients.

Background: Incidence of femoral neck fracture has risen with the aging of the population and has critical implications with regard to patient death, functional dependence, and social costs. Screw fixation using triangular configurations and calcar placement are still the preferred treatment for nondisplaced femoral neck fracture, to reduce the risk of loss of reduction and nonunion. However, this method is still controversial in terms of the effects of screw trajectory, including parallel or nonparallel configurations, on fixation of femoral neck fractures.

Worsen depression after viscosupplementation treatment for geriatric people with knee osteoarthritis?

Knee osteoarthritis (OA) in older people may result in psychological impairment, including anxiety and depression. This study investigates the effect of intraarticular hyaluronic acid injection (IAHA) on geriatric patients with OA. A total of 102 geriatric patients with knee OA undergoing IAHA were prospectively enrolled in this study.

Effectiveness of Strontium Ranelate in the Treatment of Rat Model of Legg-Calve-Perthes Disease.

Background: Legg-Calve-Perthes disease (LCPD) causes osteonecrosis of the femoral head (ONFH) by temporarily interrupting the blood supply in children. Even with potential toward bone regeneration and revascularization in LCPD, the prognosis depends on the deformity of femoral heads, and successful rate with the current treatments varies. Antiresorptive therapy such as bisphosphonate, which maintains mechanical stability of the femoral head by inhibiting necrotic bone resorption, has proven effective in animal models.

Participation of GATA-3 in regulation of bone healing through transcriptional upregulation of bcl-x expression.

We have previously demonstrated the expression of GATA-DNA-binding protein (GATA)-3, a transcription factor, in osteoblasts and have verified its function in transducing cell survival signaling. This translational study was further designed to evaluate the roles of GATA-3 in regulating bone healing and to explore its possible mechanisms. A metaphyseal bone defect was created in the left femurs of male ICR mice.

Single-Stage Cartilage Repair Using Platelet-Rich Fibrin Scaffolds With Autologous Cartilaginous Grafts.

Background: To avoid complicated procedures requiring in vitro chondrocyte expansion for cartilage repair, the development of a culture-free, 1-stage approach combining platelet-rich fibrin (PRF) and autologous cartilage grafts may be the solution.

Purpose: To develop a feasible 1-step procedure to combine PRF and autologous cartilage grafts for articular chondral defects.

Study Design: Controlled laboratory study Methods: The chemotactic effects of PRF on chondrocytes harvested from the primary culture of rabbit cartilage were evaluated in vitro and ex vivo.

Arthroscopic extended rotator interval release for treating refractory adhesive capsulitis.

Purpose: To present the clinical results of arthroscopic extended rotator interval release with a stretching program for treating refractory adhesive capsulitis.

Study Design: Case series; level of evidence, 4.

Methods: Arthroscopy-assisted extended rotator interval tissue release including anterior capsular was performed in 26 patients with refractory adhesive capsulitis.

Autoclaved metal-on-cement spacer versus static spacer in two-stage revision in periprosthetic knee infection.

Background: Periprosthetic knee infection is troublesome for Orthopedic surgeons and a catastrophy for patients. Reported rates of periprosthetic joint infection following primary total knee arthroplasty (TKA) are 0.39-2%.

Control of body's center of mass motion relative to center of pressure during uphill walking in the elderly.

Uphill walking places more challenges on the locomotor system than level walking does when the two limbs work together to ensure the stability and continuous progression of the body over the base of support. With age-related degeneration older people may have more difficulty in maintaining balance during uphill walking, and may thus experience an increased risk of falling. The current study aimed to investigate using gait analysis techniques to determine the effects of age and slope angles on the control of the COM relative to the COP in terms of their inclination angles (IA) and the rate of change of IA (RCIA) during uphill walking.

Acute compartment syndrome secondary to disruption of the perforating branch of the peroneal artery following an acute inversion injury to the ankle.

Introduction: Although ankle sprain by inversion is common in daily practice, acute compartment syndrome following ankle inversion injury is unusual. Only a few cases of this uncommon entity have been reported.

Presentation Of Case: This report describes a case of acute compartment syndrome following severe inversion of an ankle injury secondary to disruption of the perforating branch of the peroneal artery 3h after the trauma.

Clinical results of hamstring autografts in anterior cruciate ligament reconstruction: a comparison of femoral knot/press-fit fixation and interference screw fixation.

Purpose: To compare the clinical outcomes of femoral knot/press-fit anterior cruciate ligament (ACL) reconstruction with conventional techniques using femoral interference screws.

Methods: Among patients who underwent arthroscopic ACL reconstruction with hamstring autografts, 73 were treated with either a femoral knot/press-fit technique (40 patients, group A) or femoral interference screw fixation (33 patients, group B). The clinical results of the 2 groups were retrospectively compared.

Clavicular hook plate may induce subacromial shoulder impingement and rotator cuff lesion--dynamic sonographic evaluation.

Background: Clavicular hook plates are effective fixation devices for distal clavicle fractures and severe acromioclavicular joint dislocations. However, increasing number of studies has revealed that subacromial portion of the hook may induce acromial bony erosion, shoulder impingement, or even rotator cuff damage. By sonographic evaluation, we thus intended to determine whether the presence of hook plate may induce subacromial shoulder impingement and its relationship relative to surrounding subacromial structures.

Redistribution of intra- and inter-limb support moments during downhill walking on different slopes.

Downhill walking presents a greater risk of falling as a result of slipping or loss of balance in comparison with level walking. The current study aimed to investigate the effects of inclination angles on the intra-limb (inter-joint) and inter-limb sharing of the body support during downhill walking for a better understanding of the associated control strategy. Fifteen young male adults (age: 32.

One-stage arthroscopic repair of rotator cuff tears with shoulder stiffness.

Purpose: The purpose of this study is to describe a 1-stage treatment with concomitant arthroscopic capsular release and rotator cuff repair and present clinical outcomes with a minimum follow-up of 2 years.

Methods: Arthroscopic rotator cuff repair was performed in 211 consecutive patients. Forty-three patients had severe concomitant shoulder stiffness at the time of the repair.

Arthroscopic treatment of rotator cuff tears with shoulder stiffness: a comparison of functional outcomes with and without capsular release.

Background: In a single arthroscopic surgery for rotator cuff tears with a stiff shoulder, closed manipulation with or without arthroscopic capsular release has been combined with the repair. Few studies have reported functional results after this surgery, and a clinical comparison has not been reported.

Purpose: To compare functional outcomes with and without capsular release in arthroscopic treatment of rotator cuff tears with a stiff shoulder.

SATB2 participates in regulation of menadione-induced apoptotic insults to osteoblasts.

Special AT-rich sequence binding protein 2 (SATB2), a nuclear matrix attachment region-binding protein, can regulate embryonic development, cell differentiation, and cell survival. Previous studies showed that SATB2 is involved in osteoblast differentiation and skeletal development. In this study, we evaluated the role of SATB2 in oxidative stress-induced apoptotic insults to human osteoblast-like MG63 cells and mouse MC3T3-E1 cells.

Non-hardware posterior cruciate ligament reconstruction using knot/press-fit technique with periosteum-enveloped hamstrings tendon autograft.

Background: Several posterior cruciate ligament reconstruction procedures have been proposed to manage ruptures.

Purpose: This study was intended to present the clinical results of non-hardware reconstruction of posterior cruciate ligament using a knot/press-fit technique with periosteum-enveloped autogenous hamstring tendons.

Study Design: Case series; Level of evidence, 4.

Drynaria fortunei J. Sm. promotes osteoblast maturation by inducing differentiation-related gene expression and protecting against oxidative stress-induced apoptotic insults.

Aim Of The Study: Drynaria fortunei J. Sm. is one variety of the traditional Chinese medical herb Gusuibu.

Creation of a reflecting formula to determine a patient's indication for undergoing total knee arthroplasty.

Background: The aim of this study was to develop, from patients' characteristics and radiography, a formula reflecting the decision for total knee arthroplasty (TKA) in patients with a painful osteoarthritic knee.

Methods: We reviewed medical records of 193 consecutive patients who had knee osteoarthritis and underwent primary TKA surgery and 133 consecutive patients with knee osteoarthritis who did not have surgery in one institution during the preceding 5 years. Two skeletal radiologists graded, from 0 to 3, radiographic joint space narrowing (JSN), osteophytes, subchondral sclerosis, and subchondral cysts.

Runx2-mediated bcl-2 gene expression contributes to nitric oxide protection against hydrogen peroxide-induced osteoblast apoptosis.

Nitric oxide (NO) can regulate osteoblast activities. This study was aimed to evaluate the protective effects of pretreatment with sodium nitroprusside (SNP) as a source of NO on hydrogen peroxide-induced osteoblast insults and its possible mechanisms. Exposure of human osteosarcoma MG63 cells to hydrogen peroxide significantly increased cellular oxidative stress, but decreased ALP activity and cell viability, inducing cell apoptosis.

Intervertebral disk degeneration related to reduced vertebral marrow perfusion at dynamic contrast-enhanced MRI.

Objective: The purpose of this study was to use dynamic contrast-enhanced MRI to ascertain the relation between intervertebral disk degeneration and lumbar vertebral marrow blood perfusion.

Subjects And Methods: We recruited 25 patients (50 vertebral bodies) who underwent dynamic contrast-enhanced MRI of the lumbar spine. The peak signal enhancement of each vertebral body was calculated from the time signal after curve fitting of a pharmacokinetic model.

Radiographic joint space narrowing in osteoarthritis of the knee: relationship to meniscal tears and duration of pain.

Objective: The objective of this study was to assess, with knee radiography, joint space narrowing (JSN) and its relationship to meniscal tears, anterior cruciate ligament (ACL) ruptures, articular cartilage erosion, and duration of pain in patients with knee osteoarthritis.

Materials And Methods: A total of 140 patients who had knee osteoarthritis and underwent primary total knee replacement (TKR) surgery, with unicompartmental medial tibiofemoral JSN (grade 1 or greater) and normal lateral compartments, were recruited. Polytomous logistic regression was used to assess the relationship between JSN and risk factors.

Closed reduction and internal fixation for acute midshaft clavicular fractures using cannulated screws.

Background: Although most acute midshaft clavicular fractures can be successfully treated nonsurgically, surgery is more appropriate for cases with severe displaced fractures, skin tenting, initial shortening of fracture ends, and associated with multiple injuries. However, methods of surgical treatment for such fractures remain controversial. This study discusses a closed reduction and internal fixation technique for midshaft clavicular fracture.

Intermuscular cavernous lymphangioma presenting with overgrowth of fat: MRI findings.

We present a case of an intermuscular cavernous lymphangioma with predominantly composed of fatty tissue. A 58-year-old man complained a palpable painless mass over his right arm for 1 month. Magnetic resonance imaging (MRI) showed a 14-cm mass with predominantly composed of fatty tissue between long and short heads of triceps muscle.