Publications by authors named "Wei-Na Wan"

Article Synopsis
  • The study followed 61 patients with subacute thyroiditis (SAT) over 2 years to investigate early signs of hypothyroidism and changes in thyroid volume.
  • During the follow-up, thyroid volumes in SAT patients were significantly smaller than those in healthy controls and decreased over time, particularly in those who developed hypothyroidism.
  • Early maximum TSH levels measured within 3 months of SAT onset were strongly correlated with the likelihood of developing hypothyroidism, suggesting they could serve as a reliable early indicator.
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Background: Recent studies have demonstrated that microRNA-22 (miR-22) was deregulated in many types of cancers and was involved in various cellular processes related to carcinogenesis. However, the clinical significance and prognostic value of miR-22 in epithelial ovarian cancer (EOC) haven't been investigated.

Methods: 109 pairs of fresh EOC tissue and matched adjacent normal tissue specimens were collected between May 2007 and March 2013.

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The purpose of this study was to explore the expression of ATAD2 in ovarian tumor tissue as well as its relationship with degree of malignancy. Tumor tissue from 110 cases of ovarian cancer was collected in accordance with the Declaration of Helsinki for evaluation of ATAD2 expression immunohistochemistry, quantitative PCR (qPCR) and Western blotting. The correlation between the ATAD2 expression and and the prognosis of ovarian cancer was evaluated by Cox regression model.

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