Publications by authors named "Wei-Ming Lan"
China has had a long history against schistosomiasis japonica. The most serious prognosis of chronic schistosome infection is hepatic fibrosis, which develops into advanced schistosomiasis if the process is not effectively controlled. After a more than seven decades endeavor, China has gained remarkable achievements in schistosomiasis control and achieved transmission control nationwide (infection rate of schistosomes in residents and domestic animals both less than 1%) by 2015.
View Article and Find Full Text PDF[Epidemiological features and changing patterns of intestinal parasitic diseases in Jiangxi Province].
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
June 2019
Article Synopsis
- The study aimed to analyze the changes in intestinal parasitic diseases in Jiangxi Province from 1989 to 2014 to inform prevention strategies.
- Data was collected from national surveys in 1989 and 2014, revealing an 87.89% decline in the prevalence of human intestinal parasites, from 79.59% to 9.64%.
- The findings showed that while the number of parasite species decreased, soil-transmitted nematodes remained the most common parasites, with higher prevalence rates in females across all age groups.
[Investigation of infection in children in Jiangxi Province in 2014].
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
May 2018
Article Synopsis
- - The study aimed to assess the infection status in children aged 3-6 years in Jiangxi Province in 2014, to help inform prevention and control measures for parasitic diseases.
- - A survey involving 1,486 children found an overall infection rate of 13.73%, with variations based on age and income levels, peaking at 18.24% in 5-year-olds.
- - The results indicate a significant infection problem among children in the province, prompting the need for ongoing monitoring and control efforts by health authorities.
[Current status of human hookworm infection in Jiangxi Province in 2014].
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
June 2018
Article Synopsis
- * Out of 21,615 participants, 1,095 were found to be infected, reflecting a prevalence of 5.07%, with the highest rates observed in Nanfeng County and among older females.
- * Conclusions indicated a significant decline in hookworm infections, with high-risk groups identified as low-education individuals, females, and the elderly.
[Analysis of infective status of in Jiangxi Province].
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
November 2016
Objective: To understand the current prevalence of clonorchiasis in Jiangxi Province.
Methods: A survey was performed according to the scheme of the 3rd Principal Human Parasites of Jiangxi Province. Based on the ecological regions, a stratified cluster sampling method was applied by the economic and geographic situation.
[Analysis of results of technique competition for parasitic disease diagnosis in Class A tertiary hospitals in Jiangxi Province, 2015].
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
October 2016
Objective: To understand the capability of parasitic disease diagnosis among professionals from the clinic laboratory of Class A tertiary hospitals in Jiangxi Province.
Methods: The teams that took part in the competition were formed from 20 Class A tertiary hospitals, with 2 contestants per team. The competition contents included written examination and skill operation.
[Study on immune status of patients with schistosomiasis japonica in Poyang Lake region III Humoral and cellular immune characteristics between Schistosoma japonicum high and low antibody responders].
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
February 2016
Article Synopsis
- The study aimed to understand why some schistosomiasis japonica patients test negative in immune tests despite having the disease.
- Researchers tested 142 patients in the Poyang Lake region using the ELISA method and analyzed their immune responses, comparing those with high and low antibody levels.
- Findings showed that low responders had significantly lower isotype antibodies, which may explain their weak immune response, while other immune cells and cytokine levels didn't show significant differences between the two groups.
[Preservation of live eggs of Schistosoma japonicum].
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
October 2015
Article Synopsis
- - The study aimed to find the best preservation conditions for schistosome eggs to improve quality control for hatching tests by observing the hatching rates and activity of the resulting miracidia over time.
- - Schistosome eggs were collected from infected rabbits and preserved in various solutions at two temperatures (4 °C and 15 °C), with hatching rates monitored at 7-day intervals for up to 280 days.
- - Results indicated that Mili-Q water at 4 °C was the most effective preservation method, maintaining a hatching rate below 10% for 196 days, while other solutions showed significantly lower viability much sooner.
[Development and assessment of Schistosoma japonicum antibody test kit (IHA)].
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
December 2013
Objective: To develop a Schistosoma japonicum antibody test kit (IHA).
Methods: According to the requirement of Good Manufacturing Practice (GMP) and Quality Control (QC) of drugs, the components of kit as well as its preparation method and procedure were studied, and the test kit was assembled and its diagnostic effect was assessed.
Results: The sensitivity and specificity were up to 94.
[Investigation of infections of soil-transmitted nematodes in Fusheng Village of Poyang Lake area in Jiangxi Province].
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
February 2013
Article Synopsis
- The study aims to assess the prevalence of soil-transmitted nematode infections among residents in Fusheng Village, Poyang Lake area, Jiangxi Province, based on stool samples collected in 2008.
- The findings reveal a high overall infection rate of 37.97%, with notable variations: higher rates in females for Ascarid lumbricoides and hookworm, and age-related trends show increased infections with older age.
- The conclusion emphasizes the need for effective control strategies, including health education, regular treatments, proper waste management, and environmental improvements to reduce transmission.
Article Synopsis
- * The study introduces a new method called the formalin-ethyl acetate sedimentation-digestion (FEA-SD) technique, designed to effectively isolate and identify S. japonicum eggs in the feces of infected water buffaloes, improving previous methods.
- * By removing about 70% of the debris in fecal samples, the FEA-SD technique enhances visualization of the eggs under a microscope, making it a valuable surveillance tool for monitoring infection rates in animal populations, especially in areas where schistosomiasis control efforts are ongoing.
[A case of Thelazia callipaeda infection].
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi
April 2011
[A case of severe strongyloidiasis].
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi
April 2009