[Latest Research Findings on Immune Microenvironment Regulation in Jawbone-Related Diseases].

Among the bones of the whole body, the jawbone is considered the region where remodeling takes place the most actively. In this region, the homeostasis of the bones is maintained by the balanced activities of osteoblasts and osteoclasts. The bone immune microenvironment can simultaneously regulate osteoblasts and osteoclasts.

[Role of m A Reader YTHDC2 in Differentiation of Human Bone Marrow Mesenchymal Stem Cells].

Objective: To study the regulatory effect of YTH domain-containing protein 2 (YTHDC2), a member of N -methyladenosine (m A) readers, on the osteogenic or adipogenic differentiation of human bone marrow mesenchymal stem cells (hBMSCs).

Methods: 2 expression was knocked down by small interfering RNA (siRNA) . Osteogenic differentiation and adipogenic differentiation of hBMSCs were induced after 2 knockdown in order to study the changes in the differentiation phenotype of hBMSCs.

Comparison of Artificial Neural Networks and Response Surface Methodology towards an Efficient Ultrasound-Assisted Extraction of Chlorogenic Acid from .

Chlorogenic acid (CGA), a bioactive compound commonly found in plants, has been demonstrated possessing nutraceutical potential in recent years. However, the more critical issue concerning how to improve production efficacy of CGA is still limited. It is a challenge to harvest a large amount of CGA without prolonging extraction time.

Statistical optimization of alkaline protease production from Penicillium citrinum YL-1 under solid-state fermentation.

Proteases from halotolerant and halophilic microorganisms were found in traditional Chinese fish sauce. In this study, 30 fungi were isolated from fermented fish sauce in five growth media based on their morphology. However, only one strain, YL-1, which was identified as Penicillium citrinum by internal transcribed spacer (ITS) sequence analysis, can produce alkaline protease.

Correlation between fluorescence in situ hybridization and testicular biopsy for the prediction of spermatogenesis in 37 patients with nonobstructive azoospermia.

Objectives: We applied interphase fluorescence in situ hybridization (FISH) to testis sections to examine the evidence of spermatogenesis in patients with nonobstructive azoospermia. This technique was evaluated and compared with conventional testicular histopathologic findings for the possibility of additional clinical applications.

Methods: Thirty-seven consecutive patients with nonobstructive azoospermia were carefully evaluated clinically.