Publications by authors named "Wei-Meng Cai"
Background: Previous studies have demonstrated a significant correlation between obstructive sleep apnea (OSA) and frailty. However, the association of mean pulse oxygen saturation (MSpO) with frailty among OSA patients remains unconfirmed. This study aimed to explore this potential association using data from a multicenter, prospective cohort.
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- The study explored gut microbiota differences in patients with severe obstructive sleep apnea (OSA) and how these changes occur after three months of CPAP treatment.
- Using various analysis methods, the research found specific bacterial populations significantly altered in OSA patients compared to healthy controls and showed correlations between certain gut bacteria and blood pressure levels.
- The findings indicate that gut microbiota and metabolic pathways are notably different in OSA patients, and that CPAP therapy can meaningfully impact both gut bacteria composition and overall health.
Background: The concomitant rise in the prevalence of obstructive sleep apnea (OSA) and frailty among the elderly population has been linked to an increase in mortality rates. Despite continuous positive airway pressure (CPAP) being the gold standard treatment for OSA, its impact on incident frailty remains inadequately explored.
Methods: In this cohort study, we analyzed data from 1290 patients diagnosed with OSA, aged 60 years and older.