Protective effect of 13-methylberberine against mouse enteritis caused by MRSA.

Ethnopharmacological Relevance: The emergence and spread of antibiotic resistance bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA), urgently need to develop alternative strategies or novel antibacterial drugs. Coptis chinensis Franch., one ancient Chinese herb, has been widely used for the treatment of intestine disease, such as diarrhea.

Tanshinone IIA protected against lipopolysaccharide-induced brain injury through the protective effect of the blood-brain barrier and the suppression of oxidant stress and inflammatory response.

Brain microvascular endothelial cells are essential components of the blood-brain barrier (BBB) that acts as a selective physical barrier and plays protective roles in maintaining brain homeostasis. Tanshinone IIA (Tan IIA), isolated from , exhibited healthy effects such as antioxidant effects, anti-inflammatory effects, and cardiovascular protective effects. Here, we tried to investigate the positive effect and the potential mechanism of Tan IIA on the lipopolysaccharide (LPS)-induced brain injury in mice and brain microvascular endothelial cells .

[Effect of phospholipid composition on characteristics of liposomes containing zedoary turmeric oil].

Objective: To study the effect of phospholipids composition on pharmaceutical characteristics of liposomes containing zedoary turmeric oil (ZTO).

Methods: The ZTO was extracted supersonically by solvent and then colored by sulfuric acid-vanillin reagent. The ZTO liposomes were prepared by ethanol injection method.