Discovery and evaluation of 3-(2-isocyanobenzyl)-1-indole derivatives as potential quorum sensing inhibitors for the control of infections .

Quorum sensing (QS) inhibition stands out as an innovative therapeutic strategy for combating infections caused by drug-resistant pathogens. In this study, we assessed the potential of 3-(2-isocyanobenzyl)-1-indole derivatives as novel quorum sensing inhibitors (QSIs). Initial screenings of their QS inhibitory activities were conducted against PAO1 and CV026.