Surviving Sepsis After Burn Campaign.

Introduction: The Surviving Sepsis Campaign was developed to improve outcomes for all patients with sepsis. Despite sepsis being the primary cause of death after thermal injury, burns have always been excluded from the Surviving Sepsis efforts. To improve sepsis outcomes in burn patients, an international group of burn experts developed the Surviving Sepsis After Burn Campaign (SSABC) as a testable guideline to improve burn sepsis outcomes.

Evaluating the impact of rehabilitation nursing intervention on quality of life in patients with burn injuries: A protocol for systematic review and meta-analysis.

Background: Despite the availability of pharmacological intervention, patients with burn injuries experience pain during the treatment of wounds. Supplementary rehabilitation nursing intervention are required to enhance the wellbeing of patients sustaining injuries from burns. The present study aims to conduct a systematic exploration of the impact of rehabilitation nursing intervention on the wellbeing in patients sustaining burn injuries.

Epidemiology and outcome analysis of facial burns: A retrospective multicentre study 2011-2015.

Background: The head and neck regions are frequent sites of burns, but few studies have analysed and reported the epidemiology of facial burns. As the face is the centre of one's identity and persona, facial injuries often result in physical and psychological morbidity. The aim of this article is to describe the epidemiology and outcome of facial burns in China and to suggest future preventive strategies.

[Treatment of thoracic and abdominal cavity perforation complicated by Henoch-Schonlein purpura nephritis in a patient with high-voltage electric burn].

A 55-year-old male patient suffered from severe high-voltage electric burn with an area of 20%TBSA full-thickness injury. The injury involved the distal end of left upper limb, right trunk, and whole abdominal wall. Fracture of the 7th-10th ribs was found in the right side of chest, with perforation of abdominal cavity, and bilateral pleural effusion was found.

[An overview on the establishment of the system of burn prevention and treatment in China by comparing with that of foreign countries].

The number of burn patients in China is still huge because of the demographic and socio-economical reasons. Distinguished achievements have been made in Chinese burn surgery during decades of development, with a generally acknowledged high survival rate of burn victims. However, there are still many problems, including an emphasis on the treatment rather than on prevention, poor pre-hospital care system, unbalanced development of burn centers, shortage of burn rehabilitation and psycho-social support, shortage of financial support, and underdevelopment of social charity for burn patients.

[Change in expression of vascular endothelial growth factor in serum and wound tissue of rats with electrical burns].

Objective: To observe the change in expression of vascular endothelial growth factor (VEGF) in serum and wound tissue of rats with electrical burn (EB), and to explore its regulation mechanism in the pathological changes of EB.

Methods: Sixty-four SD rats were divided into normal control group (n = 8) and EB group (n = 56) according to the random number table. Eight rats in EB group were sacrificed at post injury hour (PIH) 6 and on post injury day (PID) 1, 3, 7, 14, 21, and 28, to collect wound muscle tissue and serum samples.

[Research into the prevention and treatment of burns due to specific causes should be highly strengthened].

So far there is no clear and accurate definition for burns due to specific causes, though they are encountered sometimes. Burns due to specific causes sometimes are neglected because of their low incidence, and many surgeons, even burn specialists are not familiar with them because of low incidence, thus leading to poor results in the treatment. Burns due to specific causes are often involved in complicated and compound injuries.

[Role of biological protective dressing in microskin grafting in rabbit].

Objective: To study the effect of biological protective dressing made from porcine peritoneum in covering wounds with microskin grafts.

Methods: Twenty New Zealand rabbits were divided into ten couples according to the random number table. Rabbits in each couple underwent surgery at the same time.

[Treatment of facial pigmentation after burns with traditional Chinese medicine mask and skin care].

Objective: To observe the effects of traditional Chinese medicine mask combined with skin care in the treatment of facial pigmentation after burns.

Methods: Forty-one patients with facial pigmentation after burns hospitalized from January 2009 to June 2010 were enrolled and divided into treatment group (n = 26, odd number) and control group (n = 15, even number) according to the visiting order. After cleaning, massaging, and steam spraying to faces, patients in treatment and control groups were respectively treated with traditional Chinese medicine mask developed by physicians in our hospital and common commercial beauty mask.

[Burn rehabilitation and community reintegration-new challenge to burn surgery in China].

Burn patients often have severe disfigurement, dysfunction, and psychological disorder after discharge, which may last for a long time, even for a whole life. These problems may prevent patients from returning to normal life and re-entering society. Because of demographic and socioeconomic reasons, the number of burn patients in China is huge.

[Distribution and vicissitude of drug resistance of Acinetobacter baumannii in burn intensive care unit of Wuhan City Hospital No.3 in three years].

Objective: To study the clinical distribution characteristics and vicissitude of antibiotic resistance of Acinetobacter baumannii (AB), and to look for the risk factors of AB infection in order to provide reasonable reference for the prevention and treatment of its infection.

Methods: Specimens of blood, venous catheters, sputum, wound exudates and pharyngeal swabs from 156 patients hospitalized in our burn ICU from January 2006 to December 2008 were collected and cultured. The clinical distribution and antibiotic resistance of AB were determined and analyzed.

[Diagnosis of the deep partial-thickness burn wound of Skh-1 mouse with Optical Coherence Tomography].

Objective: To evaluate the application value of Optical Coherence Tomography (OCT) in the diagnosis of the depth of burn wound.

Methods: Deep partial-thickness scald models of Skh-1 mice were reproduced using self-made steam scald appliance. The scald wounds were scanned with OCT 3 hours, or 3 and 8 days after injury respectively.

[Repair of electrical burns on hands with flaps].

Objective: To summarize the experiences and shortcomings of repair of wounds on hands due to electrical burns with flaps, aiming at further improvement.

Methods: Clinical data of 425 patients with electrical burn of hands admitted to Burn Institute of Wuhan, City Hospital NO. 3 & Tongren Hospital of Wuhan University from January 2000 to December 2006 were collected and summarized.

[Repair and reconstruction of penile defects due to devastating deep burn].

Objective: To summarize the experience of repair and reconstruction of penile defects as a result of devastating deep burn.

Methods: Twenty-four patients with penile defects in early or late (a half year after wound healed, the same below) stage after burn were involved. Their suspensory ligaments of penis were dissected to lengthen the penis after escharotomy with the necrotic distal part removed.

[Rescue and treatment for the mass burn casualties of yellow phosphorus explosion].

Objective: To summarize the characteristics and treatment of burn casualties of yellow phosphorus explosion, so as to share the experiences in emergency treatment.

Methods: By analyzing the data related to this accident, the characteristics of the injury and experiences of treatment for mass burn casualties from yellow phosphorous explosion were summarized.

Results: Eighty-one patients, 72 males and 9 females, were injured in a yellow phosphorus explosion.

[Application of reverse island flaps pedicled with cutaneous nerve nutrient vessels to repair defect on distal parts of extremities].

Objective: To analyze the feasibility of reverse island flaps pedicled with cutaneous nerve nutrient vessels in repairing the defect on distal parts of extremities.

Methods: Thirty patients with tissue defect in distal extremities, complicated by exposed vessels, nerve, tendons, and/or bones ,were repaired with island flaps pedicled with neurocutaneous nutrient vessel. Among them, five cases were grafted with flaps with external forearm cutaneous nerve vessels, eleven cases were grafted with flap containing sural neural nutrient vessels in its pedicle,and 14 cases with saphenous nerve nutrient vessels in the pedicles.

[Subarea ostectomy of mandible for lower face re-shaping].

Objective: Dividing the mandible into lower part of mandibular ramus, mandibular angle, mandibular body, chin, we designed subarea ostectomy for reduce the width of anterior, body, posterior part of of the lower face.

Methods: Combide with splitting ostectomy of the out layer of mandible, ostectomy of inferior border of mandible and augmentation of the chin, re-shape the mandibular angle, body, and chin, corrected the un-beauty of the lower face and side-face.

Results: From May 2003 to August 2005 , a total of twenty-three patients have been operated on by this method with satisfactory results.

[Improvement of reduction of prominent malar complex through an intraoral incision].

Objective: To improve the technique of prominent malar complex reduction.

Methods: The improvements of the operation procedure included double-oblique osteotomy of the prominent malar complex, accessorial tiny preauricular incision and the way that the complex was moved upward, inward or posteriorly. The zygomatic body was fixed with microplate screw or steelwire.

[Influence of vascular endothelial growth factor gene modification on skin substitute grafted on nude mice].

Objective: To investigate the influence of vascular endothelial growth factor (VEGF) gene modification on skin substitute grafted on nude mice.

Methods: Human fibroblasts were transfected with VEGF adenovirus vector. Then the genetic modified fibroblasts were seeded on patches of Integra artificial skin.

[Diagnosis and treatment of penetrating injury to the left ventricle].

Objective: To review our experiences with diagnosis and treatment of 6 cases of penetrating injury to the left ventricle.

Methods: Six patients were admitted to the emergency department 0.5 to 3 h after the injury, all with shock and 3 with obvious pericardiac tamponade.

[The histological changes and the revascularization process in the grafted dermal substitutes].

Objective: To observe the revascularization process and histological changes in the dermal substitutes after grafting.

Methods: Twenty-one SD rats were enrolled in the study and were randomly divided into swine acellular dermal matrix (sADM), human acellular dermal matrix (hADM), and artificial dermal equivalent (Integra) groups according to different dermal substitutes grafted underneath the skin of SD rats. The gross appearance of the grafts was observed, and the tissue biopsies were harvested at 2, 3, 4, 7, 10, 14, 21, 30, 60, 90, 120, 150, 180 post grafting day (PGD) for the observation of the revascularization process and their histological changes.

[Optimal time for the administration of rhGH in severely burned patients--analysis of the dynamic changes of IGF axis and blood sugar].

Objective: To investigate the effects of recombinant human growth hormone (rhGH) on the changes in serum insulin-like growth factor-I (IGF-I), IGF binding protein 3 (IGFBP-3) and blood sugar in severely burned patients, so as to validate the optimal time of rhGH administration.

Methods: Forty severely burned patients were enrolled in the study and were randomly divided into control (C), treatment 1 (rhGH given from 7 - 9 PBD, T1) and treatment 2 (rhGH from 10 - 14 PBD, T2) groups. The dynamic changes in serum IGF-I, IGFBP-3 and blood sugar on the 1, 3, 5, 7, 10, 14 and 21 PBDs in all 3 groups of burn patients were determined, analyzed and compared with one another.