Role Overload and Work Performance: The Role of Psychological Strain and Leader-Member Exchange.

The relation between role overload and work performance remains insufficiently understood. Drawing upon conservation of resources theory, we expected role overload to negatively relate to performance through psychological strain and this relation to be buffered by leader-member exchange (LMX). Study 1 ( = 212) examined depression as a severe type of strain that mediates between role overload and in-role performance, job dedication, and voice behavior.

Potential GM-CSF Antagonists Selected from a Peptide Phage Display Library.

Peptide phage display libraries have been successfully applied in areas of mapping antibody epitope, finding ligands for enzymes, receptors, and many other molecules. But it has been demonstrated to be very difficult to select cytokine-binders from peptide phage display libraries probably because cytokine is not so sticky as antibody that there are rare chances of capturing peptide phages during biopanning. A pVIII-based peptide phage display library was panned with the cytokine GM-CSF and some GM-CSF binding clones were selected based on high throughput screening (HTS) method and confirmed by ELISA and micropanning assays.

Phages Displaying Peptides with beta Turn Conformation.

Peptide CX(2)GPX(4)C, which was supposed to adopt a typical beta turn conformation, was displayed on the surface of filamentous phages by fusing to the N-terminus of minor coat protein g3p. The diversity of this library was 1.04x10(8).