Effects of the modified electric convulsive treatment (MECT) on cell factors of schizophrenia.

The expression of cell factors of schizophrenia and the effect of the modified electric convulsive treatment (MECT) were studied. In total, 156 patients with schizophrenia were selected, and divided into the drug group (70 cases) and the drug combined with MECT group (combined group) (86 cases) according to the treatment methods. In addition, 70 cases of healthy volunteers (control group) were selected according to the closest matching method based on 1:1 of age and gender.

Low-Dose Versus Standard-Dose Tissue Plasminogen Activator in Acute Ischemic Stroke in Asian Populations: A Meta-Analysis.

Recent studies have investigated the most efficacious dose of intravenous tissue plasminogen activator (IV-tPA) for acute ischemic stroke (AIS) patients. There remains no definitive consensus concerning the superior efficacious IV-tPA dose (standard- vs. low-dose), prompting us to perform a meta-analysis comparing the efficacy and safety profile of standard- versus low-dose IV-tPA.

[The clinical efficacy and safety of tacrolimus in patients with myasthenia gravis].

Objective: To evaluate the efficacy and safety of tacrolimus in patients with generalized myasthenia gravis (MG).

Methods: A total of 69 cases admitted to our hospital were given 2-6 mg/day tacrolimus (FK506) for 12 months. The MG absolute and relative clinical scores were used to monitor the efficacy of tacrolimus.

A cohort study on myasthenia gravis patients in China.

Clinical classification and age distribution in myasthenia gravis (MG) cases seem different between Oriental and Caucasian populations, but there have rarely been any clinical studies on MG patients from mainland China. The goal of the current study was to perform a comprehensive survey of myasthenia gravis in a hospital in China, establishing contemporary cohort data and clinical features. 1,108 unselected patients with MG attending the 309th Hospital of PLA, Beijing, China were studied during a 36-month period from July 2008 to June 2011.

[The clinical characteristics of patients with thymoma-associated myasthenia gravis].

Objective: To investigation the clinical characteristics in myasthenia gravis (MG) patients with thymomas.

Methods: A total of 856 MG patients admitted to the department during 2008.7 - 2010.

[Thymoma T helper type 17 cells and related cytokines in myasthenia gravis].

Objective: To investigate the immunoregulatory role of Th17 cell and the related cytokines in myasthenia gravis.

Methods: Totally 51 myasthenia gravis (MG) patients were divided into MG with thymomas (TM group) and the MG with normal thymus (NT group), as well as 22 healthy subjects as controls. Th17 cells from peripheral blood mononuclear cells were measured by flow cytometry.

[The clinical characteristics of early-onset versus late-onset types of myasthenia gravis].

Objective: To compare the clinical characteristics of early-onset and late-onset myasthenia gravis (MG).

Methods: A total of 819 MG patients admitted in our department during the same period were reviewed retrospectively. The patients with MG were divided into two groups by the age of onset, which were the early-onset MG (< 49 years) and late-onset MG (≥ 50 years).

[Clinical value of low-frequency repetitive nerve stimulation in myasthenia gravis].

Objective: To explore the value of low-frequency repetitive nerve stimulation (RNS) in the diagnosis of myasthenia gravis (MG).

Methods: A total of 436 MG patients admitted during the period of July 2008 and August 2010 and undergoing the repetitive nerve stimulation test were reviewed retrospectively. We analyzed the positive rates of RNS in MG patients and compared the abnormalities in different nerves including facial, accessory, axillary and ulnar nerves.

[The clinical features of myasthenia gravis associated with thyroid abnormalities].

Objective: To analyze the clinical characteristics of myasthenia gravis (MG) associated with thyroid abnormalities.

Methods: A total of 300 MG patients admitted to the department of neurology from July 2008 to September 2009 were reviewed retrospectively. Based on the thyroid function and abnormality of thyroid related antibodies (thyroglobulin antibody and peroxidase antibody), the patients with MG were divided into two groups (260 cases without thyroid disease and 40 cases with thyroid abnormalities).