Publications by authors named "Wei Zhu Ju"

Introduction: The incidence and clinical outcome of pericardial and pleural effusion after cryoballoon ablation (CBA) or radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF) have not been fully investigated.

Methods: A total of 60 patients with paroxysmal AF were treated with either CBA (n = 30) or RFCA (n = 30) groups, with assessment of serum troponin I level, left atrial pulmonary vein computed tomography (CT) angiography and echocardiography within 24 hours before ablation, and serum troponin I level at 12 hours, and chest CT and echocardiography within 24 hours postablation. Repeat chest CT was performed 1 month after the index procedure in patients with pericardial or pleural effusion.

View Article and Find Full Text PDF

Objective: Hypertension is a significant risk factor for atrial fibrillation (AF). The role of pulmonary vein (PV) remodeling in the mechanistic association between hypertension and AF is not definitive. In this study, we aimed to identify changes in the electrophysiology and histology in PVs in two-kidney, one-clip (2K1C) hypertensive rats.

View Article and Find Full Text PDF

Background/aims: Chronic myocardial infarction (MI) results in the formation of arrhythmogenic substrates, causing lethal ventricular arrhythmia (VA). We aimed to determine whether mesenchymal stem cells (MSCs) carrying a hepatocyte growth factor (HGF) gene modification (HGF-MSCs) decrease the levels of arrhythmogenic substrates and reduce the susceptibility to developing VA compared with unmodified MSCs and PBS in a swine infarction model.

Methods: The left descending anterior artery was balloon-occluded to establish an MI model.

View Article and Find Full Text PDF

Objective: To evaluate the clinical characteristics and long-term results of non-pulmonary veins (PV) trigger ablation in patients with paroxysmal atrial fibrillation (AF).

Methods: Eighty-six patients [48 men, mean age (52.3 ± 10.

View Article and Find Full Text PDF

Objective: To report the single-center clinical experience of catheter ablation of epicardial accessory pathway associated with coronary sinus musculature.

Methods: The data of 721 cases of left sided accessory pathway ablation were retrospectively analyzed. Ablation in the coronary sinus was performed in 17 (2.

View Article and Find Full Text PDF

Objective: To evaluate the acute and long-term effects of catheter radiofrequency ablation for the treatment of ventricular arrhythmia storm (VAS) post implantable cardioverter-defibrillators (ICD) implantation.

Methods: Acute and long-term effects of catheter radiofrequency ablation for the treatment of VAS post ICD implantation were retrospectively assessed in 11 patients from September 2008 to August 2011.

Results: A total of 15 ablation procedures were performed in 11 patients.

View Article and Find Full Text PDF

Objective: To explore the topographic distribution and long-term outcome of catheter ablation for focal atrial tachycardia (AT).

Method: The data of 207 patients who underwent electrophysiologic study for AT were retrospectively analyzed.

Results: A total of 200 AT were identified in 185 patients.

View Article and Find Full Text PDF

Objective: To summarize the clinical characteristics of congenital ventricular aneurysm and diverticula in inland China.

Methods: To identify the literature of congenital aneurysm and diverticula from Wanfang, China National Knowledge Infrastructure (CNKI) and PubMed databases, and to analyze the clinical characteristics of congenital aneurysm and diverticula from January of 2001 to December of 2009.

Results: A total of 116 patients [78 men, 1 - 80 (33.

View Article and Find Full Text PDF

Background: Radiofrequency catheter ablation (RFCA) necessarily produces an area of myocardial necrosis. However, the difference of the extent of myocardial injury between circumferential pulmonary vein isolation (CPVI) and complex fractionated atrial electrograms (CFAE) ablation in patients with atrial fibrillation (AF) has not been investigated before.

Methods: Twenty-nine consecutive male patients (n = 29) with either paroxysmal or persistent AF were selected for CPVI or CFAE ablation.

View Article and Find Full Text PDF

Objective: To evaluate the effects of N-acetylcysteine (NAC) on hypoxia-reoxygenation (H/R) injury induced apoptosis in neonatal rat cardiomyocytes.

Methods: Neonatal rat cardiomyocytes were cultured for 48 h and then randomized into control group, H/R group and H/R + NAC group. Cardiomyocytes underwent hypoxia for 6 h, reoxygenation for 72 h in the absence (H/R group) or presence (H/R + NAC group) of NAC (100 micromol/L).

View Article and Find Full Text PDF

Introduction: the aim of this study was to delineate the electroanatomic substrates of right-sided free wall (RFW) accessory pathways (APs) that were refractory to conventional catheter ablation utilizing 3-dimensional (3-D) mapping.

Methods And Results: eleven patients with RFW APs that failed initial conventional catheter ablation(s) by a mean of 1.9 ± 0.

View Article and Find Full Text PDF

Objective: To investigate the prevalence of Epsilon wave in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC).

Methods: The epsilon wave was detected in 32 patients [24 men, mean age (42.3 +/- 13.

View Article and Find Full Text PDF

1. The purpose of the present study was to explore the relationship between electrocardiogram (ECG) patterns of right ventricular outflow tract (RVOT) premature ventricular contractions and the three-dimensional distribution of the target sites. 2.

View Article and Find Full Text PDF