Analysis of prognosis of neurological sequelae in children with carbon monoxide poisoning.

This study retrospectively analyzed children admitted to the Fourth Affiliated Hospital of Guangxi Medical University for CO (carbon monoxide) poisoning from January 2018 to December 2022 and followed up on their neurological sequelae for a long time. The study was approved by the Ethics Committees of the Fourth Affiliated Hospital of Guangxi Medical University (the identification code was KY2023131) and informed consent was obtained from all participants and/or their legal guardians. The study complied with the Declaration of Helsinki.

Spatiotemporal migration of dust pollution during the tunnel mucking process and development of dust removal trolley based on computational fluid dynamics technology.

During tunnel construction, the protracted mucking phase poses significant occupational health risks, particularly from dust exposure. This study delves into comprehensive numerical simulations to examine the spatiotemporal dynamics of dust particles during the mucking process. A distinct 'bimodal pattern' was characterized by higher concentrations in the mucking area (0-30 m) and the inverted arch area (60-110 m), where concentrations exceed 30 mg/m3 under all conditions.

A layered Janus metastructure for multi-physical quantity detection based on the second harmonic wave.

In the field of nonlinear optics and physical quantity detection, the use of the second harmonic wave (SHW) generated in ferroelectric crystals is proposed to realize multi-physical quantity detection with the Janus property. In view of the single physical quantity detected by the current research and the single application scenario, this paper proposes a multi-functional and novel nonlinear Janus metastructure (NJMS), which exploits the SHW to achieve highly sensitive multi-physical quantity detection in the terahertz frequency range and shows Janus properties in both the forward and backward directions of the system. The NJMS is realized to detect refractive indices, thicknesses, and angles with different modes in the forward and backward directions.

Safety and efficacy of intravenous recombinant human prourokinase for acute ischaemic stroke within 4·5 h after stroke onset (PROST-2): a phase 3, open-label, non-inferiority, randomised controlled trial.

Background: Intra-arterial prourokinase has been shown to be a promising thrombolytic agent in patients with acute ischaemic stroke. Given the global shortage of thrombolytics, we aimed to assess the non-inferiority of intravenous recombinant human prourokinase compared with alteplase in patients with acute ischaemic stroke who were ineligible for or who refused endovascular thrombectomy.

Methods: PROST-2 was a phase 3, open-label, non-inferiority, randomised controlled trial conducted at 61 hospitals in China.

Impact of computing infrastructure on carbon emissions in China.

The development of computing infrastructure has brought about increased productivity, but it has also brought about energy consumption and carbon emissions. Based on the panel data and business enterprise registration data of 279 prefecture-level cities from 2008 to 2021, using the econometric model system, this study investigates the relationship between computing infrastructure and carbon emission intensity, yielding several findings: First, our result finds that there is an inverse "U-shaped" pattern in the association between carbon emission intensity and computing infrastructure. According to several robustness tests, such as using IV method and PCSD model, the research conclusion still holds.

New insights into interfacial dynamics and mechanisms of biochar-derived dissolved organic matter on arsenic redistribution in Schwertmannite.

Biochar is extensively utilized for the remediation of environments contaminated with heavy metals (HMs). However, its derived-dissolved organic matter (BDOM) can interact with iron oxides, which may adversely influence the retention of HMs. This study investigates the effect of BDOM derived from tobacco stalk (TS) and tobacco petiole (TP) biochar on the redistribution behavior of As(V) in acid mine drainage (AMD)-impacted environments, particularly concentrating on the interactions with Schwertmannite (Sch).

Heatwaves increase the polystyrene nanoplastic-induced toxicity to marine diatoms through interfacial interaction regulation.

Marine heatwaves, prolonged high-temperature extreme events in the ocean, have increased worldwide in recent decades. Plastic pollution is widespread in the ocean, and the continuous weathering of plastics leads to a substantial release of nanoplastics (NPs). However, the interactive impacts and in-depth mechanisms of heatwaves and NPs on diatoms are largely unknown.

Age-related variations in heart rate variability profiles among patients with schizophrenia and major depressive disorder.

Patients with psychiatric disorders exhibit general autonomic dysregulation and elevated cardiovascular risks, which could be indexed by heart rate variability (HRV). However, HRV is susceptible to age and other patient-specific factors. This study aimed to investigate the HRV profile and age-related variations, as well as the potential influence of sex, BMI, and HR on HRV in psychiatric populations.

Osteogenesis promotion on MC3T3 by micro-area potential difference (MAPD) on titanium alloy.

The ability of osseointegration of implants is an important factor in ensuring the long-term stability of bone implants in their recipient sites. In this paper, Ti-M titanium alloys with different surface micro-area potential difference (MAPD) were prepared and the adhesion, proliferation, spreading, and differentiation behavior of osteoblasts (MC3T3) on the surface of Ti-M alloy were investigated in detail to reveal the effect of MAPD on cell compatibility and osteogenic differentiation. The results showed that the alloy with high MAPD facilitated bone differentiation, demonstrating that MAPD significantly enhanced the alkaline phosphatase activity and mineralization ability of osteoblasts, and upregulated the expression of osteogenic differentiation-related factors.

Two case reports of breast cancer combined with synchronous primary intrahepatic cholangiocarcinoma/mixed liver cancer.

Rationale: This case report discusses multiple primary malignant tumors, which refer to the occurrence of 2 or more different histological types of malignant tumors simultaneously or successively in the same individual.

Patient Concerns: We present 2 female patients who were admitted to the hospital due to a "left breast mass" and were found to have multiple solid masses in the liver upon imaging.

Diagnoses: Postoperative pathology revealed that one patient had breast invasive ductal carcinoma was complicated with primary intrahepatic cholangiocarcinoma and mixed hepatocellular carcinoma with intrahepatic cholangiocarcinoma.

Landscape of cardiorenal syndrome research: A bibliometric analysis.

To comprehensively review cardiorenal syndrome (CRS)-related research, this study analyzes its whole landscape and future trends from a bibliometric perspective. Using "cardiorenal syndrome" as the key word, a representative dataset of CRS was constructed in the Web of Science Core Collection (Science Citation Index Expanded) database up to November 2023. VOSviewer (version 1.

Driving mechanisms of the spatial distribution of industrial parks and the relative hazard level of the surrounding environment.

Analyzing the formation mechanisms of industrial parks and quantitatively evaluating the related hazard levels are important for understanding the development and planning of industrial parks, but there is currently a lack of relevant research. In this study, Beijing was taken as a case study. The analysis results showed that (1) the overall spatial distribution of industrial parks in Beijing followed a clustering pattern, with nested spatial distribution pattern, where larger structures contributed 53.

Clinical observation on warming needle moxibustion combined with rehabilitation techniques in the treatment of anterior disc displacement without reduction.

Objective: To observe the effect of warming needle moxibustion combined with rehabilitation techniques on clinical symptoms and quality of life of patients with anterior disc displacement without reduction (ADDwoR).

Methods: This randomized controlled trial included 66patients, with ADDwoR, attending the Hangzhou Hospital of Traditional Chinese Medicine. Patients were assigned to the Experimental (12 sessions of warming needle moxibustion combined with rehabilitation manipulation therapy) and Control (rehabilitation therapy only) group (n = 33, each).

Strengthened High-Concentration Quasi-Solid Electrolytes for Lithium Metal with Ultralong Stable Cyclability.

The lithium metal batteries coupled with nickel-rich LiNiCoMnO ( > 0.7) cathodes hold promise for surpassing the current energy density limit of lithium-ion batteries. However, conventional electrolytes containing free active solvents are highly susceptible to decomposition, particularly at the interfaces of lithium anode and high-voltage cathode.

Black phosphorus nanoplatform coated with platelet membrane improves inhibition of atherosclerosis progression through macrophage targeting and efferocytosis.

Plaque rupture in atherosclerosis (AS) is a major cause of acute cardiovascular events. Macrophage-induced inflammatory responses and accumulation of excess reactive oxygen species (ROS) primarily induce unstable plaques. Therefore, targeting ROS clearance and functional modulation of macrophages are clinically crucial for improving plaque stability and inhibiting AS progression.

Unravelling depth layers of microbial communities, nitrogen transformation rate, and extracellular polymeric substances in anammox granules.

Anammox granules harbor a variety of bacteria, with each granule layer providing a niche for bacteria with specific metabolic functions. To investigate microbial distribution, nitrogen transformation rates, and extracellular polymeric substance (EPS) content across the depth layers of anammox granules, granules sized 0.9-2.

Keystone design perforator island flap for reconstruction of vermillion defects: A case series and literature review.

Background: Many repair techniques have been recommended to treat lower lip defects. Although effective in many instances, some techniques are accompanied by complications, such as flap necrosis, dysesthesia of the lip, lip flattening, shortening, and loss of the vermillion roll. This study aimed to report the use of keystone design perforator island flap (KDPIF) in small to medium defects to achieve an effective and functional reconstruction of vermillion defects after Mohs surgery for lip cancer.