Potential Biochemical Mechanisms of Brain Injury in Diabetes Mellitus.

The goal of this review was to summarize current biochemical mechanisms of and risk factors for diabetic brain injury. We mainly summarized mechanisms published in the past three years and focused on diabetes induced cognitive impairment, diabetes-linked Alzheimer's disease, and diabetic stroke. We think there is a need to conduct further studies with increased sample sizes and prolonged period of follow-ups to clarify the effect of DM on brain dysfunction.

[Succession Characteristics and Water Quality Responsiveness Evaluation of FG and MBFG in Yanlong Lake Water Source Ecological Purification System].

To explore the water purification efficiency and phytoplankton control efficiency of the water source ecological purification system, and evaluate the effectiveness of the functional group (FG) and morphology-based functional group (MBFG) in response to the internal environment and water quality of the water source ecological purification system, in the summer of 2018, the water quality and phytoplankton functional groups of each unit of the Yanlong Lake ecological purification system were monitored and analyzed. The results showed that the Yanlong Lake water source ecological purification system can effectively purify the water. The average values of total phosphorus, total nitrogen, dissolved oxygen, and turbidity in the influent water were 0.

Reductive Stress-Induced Mitochondrial Dysfunction and Cardiomyopathy.

The goal of this review was to summarize reported studies focusing on cellular reductive stress-induced mitochondrial dysfunction, cardiomyopathy, dithiothreitol- (DTT-) induced reductive stress, and reductive stress-related free radical reactions published in the past five years. Reductive stress is considered to be a double-edged sword in terms of antioxidation and disease induction. As many underlying mechanisms are still unclear, further investigations are obviously warranted.

5-Methoxyindole-2-Carboylic Acid (MICA) Fails to Retard Development and Progression of Type II Diabetes in ZSF1 Diabetic Rats.

5-Methoxyindole-2-carboxylic acid (MICA) is a well-established reversible inhibitor of mitochondrial dihydrolipoamide dehydrogenase (DLDH). This chemical, as an indole derivative, has been shown to be neuroprotective against ischemic stroke injury when administered either before or after ischemic stroke in animal models. MICA has also been studied as a potential antidiabetic agent by numerous investigators, though the underlying mechanisms remain sketchy.

[Analysis of the Optical Properties and Factors Influencing DOM in an Ecological Purification System: A Case Study of Yanlong Lake in Spring].

An investigation the optical properties and spatial distribution of dissolved organic matter (DOM) in an ecological purification system and the primary factors that affect the optical properties of the DOM was conducted. Taking the Yanlong Lake ecological purification system as an example, data from spring 2017 and 2018 were compared. The results show that the concentrations of total phosphorus and total nitrogen and the permanganate index in Yanlong Lake were 0.

Indoor Heating Drives Water Bacterial Growth and Community Metabolic Profile Changes in Building Tap Pipes during the Winter Season.

The growth of the bacterial community harbored in indoor drinking water taps is regulated by external environmental factors, such as indoor temperature. However, the effect of indoor heating on bacterial regrowth associated with indoor drinking water taps is poorly understood. In the present work, flow cytometry and community-level sole-carbon-source utilization techniques were combined to explore the effects of indoor heating on water bacterial cell concentrations and community carbon metabolic profiles in building tap pipes during the winter season.

Impact of short-term climate variation and hydrology change on thermal structure and water quality of a canyon-shaped, stratified reservoir.

Climate variation can have obvious effects on hydrologic conditions, which in turn can have direct consequences for the thermal regime and quality of water for human use. In this research, weekly surveys were conducted from 2011 to 2013 to investigate how changes of climate and hydrology affect the thermal regime and water quality at the Heihe Reservoir. Our results show that the hydrology change during the flooding season can both increase the oxygen concentration and accelerate the consumption of dissolved oxygen.

Vertical Distribution of Bacterial Community Diversity and Water Quality during the Reservoir Thermal Stratification.

Reservoir thermal stratification drives the water temperature and dissolved oxygen gradient, however, the characteristic of vertical water microbial community during thermal stratification is so far poorly understood. In this work, water bacterial community diversity was determined using the Illumina Miseq sequencing technique. The results showed that epilimnion, metalimnion and hypolimnion were formed steadily in the JINPEN drinking water reservoir.

Structure, photoluminescent properties and photocatalytic activities of a new Cd(II) metal-organic framework.

A new metal-organic framework, [Cd(TDC)(bix)(H2O)]n (H2TDC = thiophene-2,5-dicarboxylic acid; bix = 1,4-bis(imidazol-1-ylmethyl)benzene), has been synthesized under hydrothermal conditions and structurally characterized by elemental analysis, infrared spectroscopy, thermogravimetric analysis, UV-vis and single X-ray diffraction. Cd-MOF is a 2D infinite layer framework, which is further interconnected by hydrogen-bond interactions leading to a 3D supramolecular architecture. The photoluminescent properties of the Cd-MOF were investigated and this compound shows intense fluorescent emissions in the solid state.