Zhen Ci Yan Jiu
October 2024
Scalp-electroacupuncture (scalp-EA) is an effective traditional Chinese medicine characteristic therapy for ischemic stroke and frequently employed in clinical practice, but there is still lack of normative standard of stimulation parameters. After searching the relevant articles, we summed up the stimulation parameters of scalp-EA for ischemic stroke from 5 aspects: 1) stimulating frequency (Low frequency is better when continuous waveform is used, and high frequency is better when dense-sparce waveform or discontinuous waveform employed), 2) waveform (Dense-sparce or discontinuous waves are better than continuous waves), 3) intensity (A tolerable stimulation strength may result in better outcomes), 4) needle retention time (In general, the needle retention time is 30 min, but still needing being determined), treatment course (Some studies showed that once a day EA for 3 continuous days is effective, 7 days, significantly effective, 14 days, further enhanced in the therapeutic effect), and 5) intervention time window (Generally, EA intervention within 6 h was mostly effective, shown by animal study). However, these parameters do not exist independently, and they can influence and interact with each other.
View Article and Find Full Text PDFPhotobiomodul Photomed Laser Surg
March 2024
The development of cutting-edge techniques to study specific brain regions and neural circuits that regulate sleep-wake brain states and general anesthesia (GA), has increased our understanding of these states that exhibit similar neurophysiologic traits. This review summarizes current knowledge focusing on cell subtypes and neural circuits that control wakefulness, rapid eye movement (REM) sleep, non-REM sleep, and GA. We also review novel insights into their interactions and raise unresolved questions and challenges in this field.
View Article and Find Full Text PDFHydrogen evolution reaction (HER) has a dominant function in energy conversion and storage because it supplies a most effective way for converting electricity into sustainable high-purity hydrogen. Layered double hydroxides (LDHs) have shown promising performance in the process of electrochemical water oxidation (a half-reaction for water splitting). Nevertheless, HER properties have not been well released due to the structural characteristics of related materials.
View Article and Find Full Text PDFObjective: To explore the role of RN181 in the pathogenesis of oral squamous cell carcinoma (OSCC) cells via mediating ERK/MAPK signaling.
Methods: The expression of RN181 was detected in OSCC tissues and cells. CAL27 and SCC-15 cells were divided into Control, Empty, RN181, si-RN181, U0126 (an inhibitor of ERK/MAPK pathway) and si-RN181 + U0126 groups.
Although general anesthesia (GA) enables patients to undergo surgery without consciousness, the precise neural mechanisms underlying this phenomenon have yet to be identified. In addition to many studies over the past two decades implicating the thalamus, cortex, brainstem, and conventional sleep-wake circuits in GA-induced loss of consciousness (LOC), some recent studies have begun to highlight the importance of other brain areas as well. Here, we found that population activities of neurons expressing dopamine D1 receptor (D1R) in the nucleus accumbens (NAc), a critical interface between the basal ganglia and limbic system, began to decrease before sevoflurane-induced LOC and gradually returned after recovery of consciousness (ROC).
View Article and Find Full Text PDFThe water oxidation reaction plays a major role in many alternative-energy systems because it provides the electrons and protons required for the use of renewable electricity. We report the tuning of the iron molybdate (FeMoO) electron structure via a coupled interface between the catalytic centers and the substrate. Our developed FeMoO catalysts can provide a 50 mA cm current density at 1.
View Article and Find Full Text PDFObjective: To discover the role of miR-590-5p in oral squamous cell carcinoma (OSCC) progression and the corresponding mechanism via the targeting RECK.
Methods: OSCC (n=85) and normal oral tissues (n=60) were collected to quantify the miR-590-5p expression by using qRT-PCR. Then SCC-15 and OEC-M1 cells were selected and divided into Mock, inhibitor NC, miR-590-5p inhibitor, si-RECK and miR-590-5p inhibitor + si-RECK groups.
We report FeOOH supported on Ni foam which enables highly efficient UOR electrocatalysis and can be readily produced through a hydrolysis reaction. Our developed UOR catalyst as the anode can provide a current density of 200 mA cm at 1.427 V vs.
View Article and Find Full Text PDFFront Chem
September 2020
The study aims to investigate how DANCR can alter the growth and metastasis of oral squamous cell carcinoma (OSCC) cells by regulating miR-216a-5p. The expression of DANCR and miR-216a-5p in OSCC patients and cells were measured. SCC15 and CAL-27 cells were selected to divide into Control, sh-NC, DANCR shRNA, DANCR, miR-216a-5p mimic, and DANCR + miR-216a-5p mimic groups.
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