Publications by authors named "Wei Wangl"
Article Synopsis
- Adenovirus-mediated gene therapy using hepatocyte growth factor (HGF) shows potential for treating coronary heart disease by promoting blood vessel growth and improving heart function, as indicated by positive preclinical studies.
- An open-label trial with 18 coronary heart disease patients evaluated the safety and effectiveness of Ad-HGF through intramyocardial injections during bypass surgery, using varying doses.
- Results showed no adverse effects and improved myocardial perfusion, especially at higher doses, suggesting Ad-HGF is well tolerated and warrants further investigation in larger trials.
