Emergency pancreaticoduodenectomy for pancreatitis-associated necrotic perforation of the distal stomach and full-length duodenum: A case report.

Background: Non-ulcerative necrosis of the stomach and duodenum is rare because of the abundant blood supply in the gastrointestinal tract. Duodenal necrosis is a rare complication of severe acute pancreatitis. Emergency pancreaticoduodenectomy (EPD) is a rare procedure, with extensive duodenal necrosis being one of its indications.

A dual-region speech enhancement method based on voiceprint segmentation.

Single-channel speech enhancement primarily relies on deep learning models to recover clean speech signals from noise-contaminated speech. These models establish a mapping relationship between noisy and clean speech. However, considering the sparse distribution characteristics of speech energy across the entire time-frequency spectrogram, constructing the mapping relationship from noisy to clean speech exhibits significant differences in regions where speech energy is concentrated and non-concentrated.

An Anti-Noise Convolutional Neural Network for Bearing Fault Diagnosis Based on Multi-Channel Data.

In real world industrial applications, the working environment of a bearing varies with time, and some unexpected vibration noises from other equipment are inevitable. In order to improve the anti-noise performance of neural networks, a new prediction model and a multi-channel sample generation method are proposed to address the above problem. First, we proposed a multi-channel sample representation method based on the envelope time-frequency spectrum of a different channel and subsequent three-dimensional filtering to extract the fault features of samples.

FGD5‑AS1 is an oncogenic lncRNA in pancreatic cancer and regulates the Wnt/β‑catenin signaling pathway via miR‑577.

The objective of the present study was to clarify the expression characteristics of long non‑coding RNA (lncRNA) FGD5 antisense RNA 1 (FGD5‑AS1) in pancreatic cancer, as well as its biological function and underlying mechanism. Reverse transcription‑quantitative polymerase chain reaction (RT‑qPCR) was utilized for the detection of FGD5‑AS1 and microRNA (miR)‑577 expression levels in pancreatic cancer tissues. Transfection was performed to upregulate or downregulate FGD5‑AS1 in pancreatic cancer cell lines.

Administration of isoliquiritigenin prevents nonalcoholic fatty liver disease through a novel IQGAP2-CREB-SIRT1 axis.

Isoliquiritigenin (ISO) is a flavonoid extracted from the root of licorice, which serves various biological and pharmacological functions including antiinflammatory, antioxidation, liver protection, and heart protection. However, the mechanism of its action remains elusive and the direct target proteins of ISO have not been identified so far. Through cell-based screening, we identified ISO as a potent lipid-lowering compound.

Cyclic helix B peptide alleviates sepsis-induced acute lung injury by downregulating NLRP3 inflammasome activation in alveolar macrophages.

Acute lung injury (ALI) exhibits high clinical morbidity and mortality rates. Our previous study has indicated that the novel proteolysis-resistant cyclic helix B peptide (CHBP) exerts an anti-inflammatory effect in mice with AKI. In the present study, we evaluated the effect of CHBP in an in vivo sepsis-induced ALI model and in vitro using lipopolysaccharide (LPS) and ATP stimulated bone marrow-derived macrophages (BMDMs).

Transorbital nonmissile penetrating brain injury: Report of two cases.

Background: Penetrating brain injury (PBI) is an uncommon emergency in neurosurgery, and transorbital PBI is a rare type of PBI. Reasonable surgical planning and careful postoperative management can improve the prognosis of patients.

Case Summary: The first case is a 68-year-old male patient who was admitted to the hospital because a branch punctured his brain through the orbit for approximately 9 h after he unexpectedly fell while walking.

Understanding Gene Therapy in Acute Respiratory Distress Syndrome.

Acute Respiratory Distress Syndrome (ARDS) and its complications remain lifethreatening conditions for critically ill patients. The present therapeutic strategies such as prone positioning ventilation strategies, nitric oxide inhalation, restrictive intravenous fluid management, and extracorporeal membrane oxygenation (ECMO) do not contribute much to improving the mortality of ARDS. The advanced understanding of the pathophysiology of acute respiratory distress syndrome suggests that gene-based therapy may be an innovative method for this disease.

Efficacy of methylphenidate for the treatment of mental sequelae after traumatic brain injury.

Background: This study aimed to evaluate the effect of methylphenidate for treating mental sequelae after traumatic brain injury (TBI).

Methods: Thirty-six patients with TBI were randomly divided into the intervention group and placebo group. The participants in the intervention group received methylphenidate, while subjects in the placebo group were administered a placebo.

Characteristics Analysis of the Thyroid Gland Surface of Normal Human with Fourier Transform Infrared (FTIR) Spectra.

In order to obtain 240 cases of the surface Fourier transform infrared (FTIR) spectra of normal human thyroid gland, 120 healthy volunteers were enrolled in this study and scanned by using two mid-infrared optical fibers equipped with an attenuated total reflectance (ATR) to probe through the skin of two lobes of thyroid gland. Then whether there were differences between the surface FTIR spectra of the right lobe and that of the left part of the normal human thyroid gland was explored by comparing the 35 variables of 12 bands, including peak positions, relative intensity ratios and full width at half maximum of FTIR spectrums. Also the spectra characteristics of unique absorbent bands that represent changes of structure and quantity of variance biochemical substances such as nucleic acids, proteins and carbohydrates were illustrated.

Oddi sphincter preserved cholangioplasty with hepatico-subcutaneous stoma for hepatolithiasis.

Aim: To evaluate the long-term outcomes of Oddi sphincter preserved cholangioplasty with hepatico-subcutaneous stoma (OSPCHS) and risk factors for recurrence in hepatolithiasis.

Methods: From March 1993 to December 2012, 202 consecutive patients with hepatolithiasis underwent OSPCHS at our department. The Oddi sphincter preserved procedure consisted of common hepatic duct exploration, stone extraction, hilar bile duct plasty, establishment of subcutaneous stoma to the bile duct.

Correlation between microRNA-21 and expression of Th17 and Treg cells in microenvironment of rats with hepatocellular carcinoma.

Objective: To study the correlation between miR-21 and Treg/Th17 ratio in the microenvironment of rats with hepatocellular carcinoma.

Methods: Diethylnitrosamine was used to build the hepatocellular carcinoma model of rats; the content of Treg cells and Th17 cells and the expression of miR-21 in the peripheral blood of rats with hepatocellular carcinoma were detected. The statistical analysis was performed on the correlation between miR-21 expression and Treg/Th17 ratio.

Phloroglucinol protects the urinary bladder via inhibition of oxidative stress and inflammation in a rat model of cyclophosphamide-induced interstitial cystitis.

Background: Phloroglucinol plays an important role in oxidative stress and inflammatory responses. The effects of phloroglucinol have been proven in various disease models. The aim of the present study was to investigate the efficacy and possible mechanisms of phloroglucinol in the treatment of interstitial cystitis (IC).

[Recent progress in diagnosis of malignant tumors by Fourier transform infrared spectroscopy].

Malignant tumors pose a serious threat to mankind health and life. As a result, early diagnosis is very important. In recent years, Fourier transform infrared spectroscopy has shown enormous development potential of cancer diagnosis.

Clinical manifestations and imaging characteristics of gliomatosis cerebri with pathological confirmation.

Objective: To explore the clinical manifestations and imaging characteristics of gliomatosis cerebri to raise the awareness and improve its diagnostic accuracy for patients.

Materials And Methods: Clinical data, imaging characteristics and pathological examination of 12 patients with GC from Jan., 2008 to Jan.

Adaptive quasi-Newton algorithm for source extraction via CCA approach.

This paper addresses the problem of adaptive source extraction via the canonical correlation analysis (CCA) approach. Based on Liu's analysis of CCA approach, we propose a new criterion for source extraction, which is proved to be equivalent to the CCA criterion. Then, a fast and efficient online algorithm using quasi-Newton iteration is developed.

Combination of (18)F-fluorodeoxyglucose positron emission tomography/computed tomography and magnetic resonance imaging is an optimal way to evaluate rheumatoid arthritisin rats dynamically.

Background: Rheumatoid arthritis (RA) is a chronic, systemic autoimmune inflammatory disorder. Many methods have been used to observe the progress of RA. The purpose of this study was to observe the progress of RA in rats with 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT), magnetic resonance (MR) imaging and arthritis score, and analyze the relationships among different methods in evaluation of RA.

Quantitative T2 mapping evaluation for articular cartilage lesions in a rabbit model of anterior cruciate ligament transection osteoarthritis.

Background: Quantitative T2 mapping has been a widely used method for the evaluation of pathological cartilage properties, and the histological assessment system of osteoarthritis in the rabbit has been published recently. The aim of the study was to investigate the effectiveness of quantitative T2 mapping evaluation for articular cartilage lesions of a rabbit model of anterior cruciate ligament transection (ACLT) osteoarthritis.

Methods: Twenty New Zealand White (NZW) rabbits were divided into ACLT surgical group and sham operated group equally.

Iterative algorithm for joint zero diagonalization with application in blind source separation.

A new iterative algorithm for the nonunitary joint zero diagonalization of a set of matrices is proposed for blind source separation applications. On one hand, since the zero diagonalizer of the proposed algorithm is constructed iteratively by successive multiplications of an invertible matrix, the singular solutions that occur in the existing nonunitary iterative algorithms are naturally avoided. On the other hand, compared to the algebraic method for joint zero diagonalization, the proposed algorithm requires fewer matrices to be zero diagonalized to yield even better performance.

[Studies on genetic diversity and phylogeny of slow-growing rhizobia isolated from Vigna radiata at main ecotypes of China].

Studies on genetic diversity and phylogeny of slow-growing rhizobia isolated from Vigna radiata at main ecotypes of China were conducted by using 16S rRNA gene PCR-RFLP, 16S rRNA gene sequencing and 16S-23S rRNA IGS PCR-RFLP assays. Results of 16S rRNA gene PCR RFLP analysis reveal that all the strains tested are clustered into three groups at the similarity of 76%. Group I contains 13 slow-growing rhizobia tested including LYG1; Group II consists of 21 strains tested and the type strains of B.

Genotypic characteristics of the rrn operon and genome of indigenous soybean Bradyrhizobia in cropping zones of China.

Four genetic assays, 16S rRNA restriction fragment length polymorphism (RFLP), 16S rRNA sequencing, 16S-23S rRNA intergenetic spacer (IGS) RFLP, and amplified fragment length polymorphism (AFLP), were conducted to determine the genotypic characteristics of 44 indigenous strains of Bradyrhizobium from soybean (Glycine max L.) cropping zones of China. The results generated from different assays showed that soybean bradyrhizobial isolates comprised four genomic groups.

[Genetic diversity and phylogeny of soybean bradyrhizobia isolated from south and north region of China].

Studies on genetic diversity and phylogeny of soybean bradyrhizobia isolated from south and north region of China were investigated through 16S rRNA gene PCR RFLP, 16S rRNA gene sequencing and 16S-23S rRNA IGS PCR RFLP assays. Results of 16S rRNA gene PCR RFLP and 16S rRNA gene sequencing analysis reveal that strains tested are ascribed into Bradyrhizobium japonicum and B. elkanii species.

[Application of two parallel Kirschner wires in internal fixation for digital replantation: experience with 14 cases].

Objective: To improve the method for internal fixation in digital replantation.

Method: In 14 cases of finger fractures (17 fingers) admitted in our hospital between October, 2000 and March, 2003, intramedullary fixation was performed with two-parallel Kirschner wires, and the effects were compared with those of other internal fixations in cases treated within the same period.

Result: All the digital fractures healed and none of the 10 patients followed up suffered nonunion or delayed healing.