Publications by authors named "Wei Ping Zhang"

Dinoflagellates, both armored and unarmored, with distinct cell wall difference, are being affected by elevated CO-induced ocean acidification (OA). However, their specific responses to OA are not well understood. In this study, we investigated the physiological and molecular response of the armored species Prorocentrum obtusidens and the unarmored species Karenia mikimotoi to OA over a 28-day period.

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  • The study investigates how the timing of sowing different crops (wheat and maize) affects their competitiveness and yield when intercropped compared to being grown separately.
  • Field experiments were conducted over two years with various sowing times and planting methods, revealing that delaying wheat sowing reduced its yield while increasing maize's, yet wheat maintained a competitive edge during growth.
  • Ultimately, aligning the sowing times of wheat and maize shifted their interaction from unbalanced to more mutually beneficial, but wheat still retained some competitive advantages despite these changes.
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  • - Nicotinamide phosphoribosyltransferase (NAMPT) is vital for producing nicotinamide adenine dinucleotide (NAD) and has been studied for its protective effects in neurodegeneration, particularly in Alzheimer's Disease, but its role in Parkinson's Disease (PD) is less understood.
  • - Research indicates that dopaminergic neurons in the substantia nigra have higher NAMPT levels, and removing NAMPT leads to the loss of these neurons, dopamine pathway impairment, and symptoms similar to PD in mice.
  • - The study suggests that NAD precursor nicotinamide ribose (NR) can counteract neurodegeneration in PD by repairing dopamine pathways and highlights the potential for using NAD precursors in
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  • - The study aimed to explore the features of high-frame-rate contrast-enhanced ultrasound (H-CEUS) in solid renal tumors by analyzing 89 renal masses from 75 patients through both qualitative and quantitative assessments.
  • - Researchers observed significant differences in various characteristics (like gender, surgical approach, and echogenicity) between benign and malignant tumors, as well as differences in wash-out patterns and enhancement uniformity between conventional contrast-enhanced ultrasound (C-CEUS) and H-CEUS.
  • - Quantitative findings showed that several time-intensity curve (TIC) parameters were notably lower in H-CEUS compared to C-CEUS for both benign and malignant tumors, indicating potential differences in tumor assessment between the
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  • * A study revealed that rising temperatures (from 22°C to 26°C) significantly influenced the dinoflagellates, enhancing growth and photosynthetic efficiency but decreasing overall nutrient content.
  • * The research highlighted that elevated temperatures interact with other stressors, leading to heightened energy production and material synthesis, showcasing the complex effects of combined environmental changes on these organisms.
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  • Central precocious puberty due to Leydig cell tumors is rare but was observed in a retrospective study of 12 children treated at Beijing Children's Hospital from 2016 to 2023.
  • The analysis included various clinical evaluations, and all patients showed abnormal hormone levels, with ten experiencing peripheral precocious puberty at admission.
  • The study found a high occurrence of central precocious puberty post-surgery, with effective treatment using gonadotropin-releasing hormone analogs, though more extensive research is recommended for future insights.
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  • - The study aimed to identify risk factors for postoperative delirium in elderly patients (average age ~71.58 years) undergoing spine surgery, analyzing data from 566 patients over two years.
  • - Univariate analysis linked several factors—such as age, duration of surgery, preoperative anxiety, blood loss, and history of opioid use—to higher incidences of delirium post-surgery, with 41 patients affected.
  • - Binary Logistic regression confirmed that age, opioid use, blood loss, preoperative anxiety, and elevated C-reactive protein levels were independent risk factors for developing delirium in this population.
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  • The research focuses on integrating carbon neutrality goals into territorial planning for Gansu Province to enhance sustainable development and reduce carbon emissions.
  • An analysis of land use carbon budgets from 87 counties over different years highlighted rising carbon emissions, with construction land being a primary source and woodlands serving as essential carbon sinks.
  • The study identified a "core-edge" model in carbon emission networks, indicating key areas in Gansu that play crucial roles in overall carbon dynamics and proposing differentiated low-carbon development strategies for effective regional management.
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  • * A total of 70 patients were analyzed, divided into three groups based on how the tumors interacted with the collecting system, with varying rates of surgery success and tumor recurrence.
  • * Overall, the results showed similar survival rates but highlighted the challenges of preserving kidney tissue while managing tumor growth and preventing long-term renal issues.
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  • Non-clear cell renal cell carcinoma (nccRCC) is a rare form of kidney cancer that can be misdiagnosed, making it crucial to identify its unique characteristics through contrast-enhanced ultrasound (CEUS).
  • This study analyzed imaging features from 21 patients with confirmed nccRCC to evaluate the effectiveness of both qualitative and quantitative CEUS in diagnosis.
  • The results revealed that nccRCC commonly shows specific traits in ultrasound imaging, like hypoechoic appearance and clear boundaries, and CEUS analysis indicated significant differences in blood flow parameters between nccRCC lesions and normal renal tissue.
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  • The study aimed to create a deep learning radiomics network (DLRN) that combines ultrasound images, radiomics, and clinical features to differentiate between parotid pleomorphic adenoma (PA) and adenolymphoma (AL).
  • A total of 287 patients were used in various cohorts for training and validating machine learning classifiers that generated different models, including logistic regression and deep learning radiomics models.
  • The DLRN model outperformed other models in distinguishing between PA and AL, demonstrating a significant enhancement in diagnostic accuracy and providing an important non-invasive solution for clinicians.
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  • Ghost introgression involves the transfer of genetic material from extinct lineages into currently existing species, with limited evidence found in plants, particularly for Carya sinensis and Carya cathayensis.
  • Researchers assembled chromosome-level genomes for these species and re-sequenced 43 C. sinensis individuals and 11 diploid hickory species to explore genetic patterns and confirm ghost introgression.
  • Their analysis, employing methods like D-statistic and BPP alongside phylogenetic network analysis, provided strong evidence of ghost introgression in C. sinensis from an extinct lineage, enhancing the understanding of Carya's evolutionary history and biogeography.
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  • - The study aimed to assess how effective high-frame-rate contrast-enhanced ultrasound (H-CEUS) is in distinguishing between two types of kidney tumors: clear cell renal cell carcinoma (CCRCC) and angiomyolipoma (AML).
  • - Researchers analyzed data from 110 patients (79 with CCRCC and 31 with AML) who underwent ultrasound and H-CEUS exams before surgery, utilizing various statistical methods to identify differences in tumor characteristics and risk factors.
  • - Results showed significant differences in clinical features and ultrasound characteristics between the two groups, particularly in aspects like blood flow and enhancement patterns, indicating H-CEUS could be a promising diagnostic tool for differentiating these tumors.
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  • This study focuses on assessing high frame rate contrast-enhanced ultrasound (H-CEUS) to differentiate between benign and malignant renal tumors in patients.
  • A total of 140 patients underwent various ultrasound examinations, and their results were compared using statistical methods to analyze differences in various characteristics of the tumors.
  • Key findings indicated significant differences in factors like gender, nodule composition, echo patterns, and blood flow between benign and malignant lesions, highlighting H-CEUS’s potential for improving diagnostic accuracy.
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  • PARP-1 activity increases significantly during cerebral ischemia/reperfusion, leading to NAD deficiency and contributing to neuronal death.
  • Activation of PARP-1 results in PARylation of key metabolic enzymes, hexokinase-1 and lactate dehydrogenase-B, disrupting energy metabolism in neurons.
  • Inhibiting PARP-1 improves enzyme activity, reduces brain injury, and, when combined with pyruvate, shows promise as a therapeutic strategy for ischemic brain injury in mice.
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  • Autopolyploidy serves as an effective model for studying how whole-genome duplication affects genomic changes; this research focuses on Cyclocarya paliurus, a species with both diploid and autotetraploid forms.
  • The study revealed that the autotetraploid genome has 64 chromosomes with clusters showing similarity in length and gene expression, alongside significant genetic structural variations.
  • It was found that many genes displayed allelic loss, particularly near structural variations and transposable elements, though genes with multiple copies had higher expression linked to stress response, indicating evolutionary advantages for autotetraploids.
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  • - The study investigates how resource complementarity, specifically phosphorus facilitation, enhances ecosystem functioning in diverse plant communities, with a focus on the species Carex korshinskyi.
  • - In pot experiments on phosphorus-deficient soils, it was found that mixtures containing C. korshinskyi produced greater biomass and improved complementarity compared to those lacking it, showing interspecific facilitation effects.
  • - A meta-analysis supports the finding that phosphorus facilitation increases the relative complementarity effect in low-phosphorus environments, highlighting the importance of root trait adaptability in enhancing plant interactions and ecosystem health.
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  • * The study focuses on two species of plants: a karst endemic species and its widely distributed relative in East Asia, using advanced genome sequencing to explore their evolutionary relationship.
  • * Findings highlight significant genetic differences between the two species, including adaptations to high calcium stress, revealing both convergent evolution traits and the early stages of speciation within their genus.
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  • 5α-reductase 2 deficiency leads to issues with testosterone conversion, resulting in abnormal urogenital development and hypospadias in affected patients.
  • The study analyzed 69 patients who underwent hypospadias surgery, showing that preoperative hormone stimulation (PHS) significantly improved penile growth.
  • Results indicated differences between one-stage and staged surgeries in terms of recovery, with specific genetic mutations influencing surgical outcomes and future development considerations.
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  • This text discusses how different species can evolve similar traits (convergent evolution) when faced with similar environmental challenges, while closely related species can diverge when adapting to extreme habitats.
  • The research focuses on two species of the Platycarya genus—Platycarya longipes and Platycarya strobilacea—by analyzing their genomes to understand the molecular processes involved in their evolutionary paths.
  • The findings suggest that P. longipes has undergone significant genetic differentiation influenced by long-term selection, particularly in the calcium influx channel gene TPC1, which may highlight a shared adaptation to high calcium environments in karst regions.
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  • - The study focuses on how different types of straw and soil environments influence the decomposition of plant litter in maize/legume intercropping systems, which are more diverse than typical agricultural monocultures.
  • - Three experiments were conducted over 341 days, exploring litter quality, soil effects on root decomposition, and the advantages of decomposing litter in its original plot versus a different plot.
  • - Results showed that different straw types significantly affected mass loss during decomposition, with varying percentages of litter mass loss observed in both 'home' and 'away' plot environments across different nitrogen levels and cropping systems.
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  • The study focuses on nephron-sparing surgery (NSS) for children with bilateral Wilms tumors (BWT) and analyzes cases from January 2008 to June 2022.
  • Of the 70 patients studied, the majority were treated with preoperative chemotherapy, resulting in a significantly higher rate of bilateral NSS compared to those who didn't receive it.
  • The findings indicate improved long-term survival rates, with a 4-year event-free survival (EFS) of 67.9% and overall survival (OS) of 89.3%, suggesting that preoperative chemotherapy enhances NSS effectiveness.
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  • The study investigates the genetic relationships within the walnut family (Juglandaceae) using data from seven chromosome-level genomes, including two newly assembled genomes.
  • Through analyses of microsynteny and gene content, the research confirms previous findings that associate Platycarya with Engelhardia, contrasting with DNA alignment methods that link Platycarya to Carya and Juglans due to past hybridization.
  • The research also suggests that Juglandaceae likely originated from hybridization events involving now-extinct or unsampled progenitors closely related to Myricaceae, with Rhoiptelea chiliantha exhibiting a unique slower evolutionary rate and a higher proportion of DNA repair genes compared to other species in the family.
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