Publications by authors named "Wei Jia Zhi"
Background: The effects of heat acclimation (HA) on the hypothalamus after exertional heatstroke (EHS) and the specific mechanism have not been fully elucidated, and this study aimed to address these questions.
Methods: In the present study, rats were randomly assigned to the control, EHS, HA, or HA + EHS groups (n = 9). Hematoxylin and eosin (H&E) staining was used to examine pathology.
Exertional heatstroke (EHS) is an emergency with a high mortality rate, characterized by central nervous system dysfunctions. This study aims to establish a Heat acclimation/acclimatization (HA) rat model in locomotion to recapitulate the physical state of human in severe environment of high temperature and humidity, and investigate the mechanism of organism protection in HA. (2) Methods: Wistar rats were exposed to 36 °C and ran 2 h/d for 21 days, acquired thermal tolerance test was conducted to assess the thermotolerance and exercise ability.
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- Microwave technology raises health concerns, particularly regarding its effects on the central nervous system, where exposure can disrupt neurotransmitter release and lead to cognitive dysfunction.
- The study investigates how microwave exposure alters the phosphorylation of SYN1, specifically focusing on the roles of kinases like Cdk5 and MEK in regulating neurotransmitter release, especially GABA.
- Findings suggest that increased levels of Cdk5 may negatively impact SYN1 phosphorylation, leading to issues in synapse formation and GABA release, which could underlie cognitive impairments associated with microwave exposure.
Article Synopsis
- * A detailed review of recent research highlights various aspects affected by microwave radiation in the brain, especially the hippocampus, including learning, memory, and brain wave patterns.
- * The studies analyzed have inconsistencies due to differing experimental parameters like frequency and power, leading to unreliable data; thus, further rigorous research is needed to clarify the relationship between microwave exposure and its biological effects.
The popularization of microwave raised concerns about its influence on health including cognitive function which is associated greatly with dendritic spines plasticity. SNK-SPAR is a molecular pathway for neuronal homeostatic plasticity during chronically elevated activity. In this study, Wistar rats were exposed to microwaves (30 mW/cm for 6 min, 3 times/week for 6 weeks).
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