Front Neuroinform
August 2024
Background: The above studies indicate that the SCZ animal model has abnormal gamma oscillations and abnormal functional coupling ability of brain regions at the cortical level. However, few researchers have focused on the correlation between brain complexity and connectivity at the cortical level. In order to provide a more accurate representation of brain activity, we studied the complexity of electrocorticogram (ECoG) signals and the information interaction between brain regions in schizophrenic rats, and explored the correlation between brain complexity and connectivity.
View Article and Find Full Text PDFAim: To assess the likelihood of dementia in individuals with type 2 diabetes (T2D), distinguishing between those with and without microvascular diseases.
Methods: Leveraging the National Health Insurance Research Database in Taiwan, we identified individuals newly diagnosed with T2D from 1 January 2009 through 31 December 2014. Multivariable Cox proportional hazard models were used to compare the risk of outcomes.
The incidence of male infertility has been increasing year by year, and one of the major causes is testicular spermatogenic epithelial injury, which affects the spermatogenic function of the testis. Ferroptosis is a novel mode of cell death and plays an important role in testicular cell injury. Some traditional Chinese medicines can intervene in the progression of testicular injury by regulating the ferroptosis pathway in testicular spermatogenic epithelia.
View Article and Find Full Text PDFPositron emission tomography (PET) targeting translocator protein 18 kDa (TSPO) can be used for the noninvasive detection of neuroinflammation. Improved in vivo stability of a TSPO tracer is beneficial for minimizing the potential confounding effects of radiometabolites. Deuteration represents an important strategy for improving the pharmacokinetics and stability of existing drug molecules in the plasma.
View Article and Find Full Text PDFFree Radic Biol Med
November 2024
Computational imaging using a Pancake lens can help reduce the size of optical systems by folded optics. However, Pancake cameras frequently exhibit inferior image quality due to stray light, low light transmission, and spatially varying aberrations. In this Letter, we propose a thin and lightweight camera comprising a polarization-based catadioptric Pancake lens and a Fourier Position encoding Network (FPNet).
View Article and Find Full Text PDFChem Commun (Camb)
September 2024
With the rapid development of sensors and other devices, precise control for the generation of new energy, especially in the context of highly stochastic wind power generation, has been strongly supported. However, large-scale wind farm grid connection can cause the power system to enter a low inertia state, leading to frequency instability. Battery energy storage systems (BESSs) have the advantages of a fast response speed and high flexibility, and can be applied to wind farm systems to improve the frequency fluctuation problem in the process of grid connection.
View Article and Find Full Text PDFThis study explores the potential of β-SnSe monolayers as a promising material for ozone (O) sensing using density functional theory (DFT) combined with the non-equilibrium Green's function (NEGF) method. The adsorption characteristics of O molecules on the β-SnSe monolayer surface were thoroughly investigated, including adsorption energy, band structure, density of states (DOSs), differential charge density, and Bader charge analysis. Post-adsorption, hybridization energy levels were introduced into the system, leading to a reduced band gap and increased electrical conductivity.
View Article and Find Full Text PDFConvalescent sera, rich in pathogen-specific antibodies, offers passive immunity to patients with infectious diseases. Screening assays using convalescent sera are crucial for evaluating therapeutic efficacy, selecting suitable serum donors, and standardizing assays. They measure antibody levels, neutralizing potential, and specificity against viruses like SARS-CoV-2, ensuring therapeutic serum contains potent antibodies.
View Article and Find Full Text PDFFiber quality improvement is a primary goal in cotton breeding. Identification of fiber quality-related genes and understanding the underlying molecular mechanisms are essential prerequisites. Previously, studies determined that silencing the gene resulted in longer cotton fibers; however, both the underlying mechanisms and whether this transcription factor is additionally involved in the regulation of cotton fiber strength/fineness are unknown.
View Article and Find Full Text PDFThe integration of terrestrial- and satellite-based quantum key distribution (QKD) experiments has markedly advanced global-scale quantum networks, showcasing the growing maturity of quantum technologies. Notably, the use of unmanned aerial vehicles (UAVs) as relay nodes has emerged as a promising method to overcome the inherent limitations of fiber-based and low-Earth orbit (LEO) satellite connections. This paper introduces a protocol for measurement-device-independent QKD (MDI-QKD) using photon orbital angular momentum (OAM) encoding, with UAVs as relay platforms.
View Article and Find Full Text PDFPYR/PYL/RCAR proteins are abscisic acid (ABA) receptors that play a crucial role in plant responses to abiotic stresses. However, there have been no research reports on potato PYL so far. In this study, a potato gene named was identified based on transcriptome data under drought stress.
View Article and Find Full Text PDFQuinoa ( Willd) sprouts are rich in bioactive compounds that offer numerous health benefits. However, limited research exists on their cultivation, nutritional value, and processing potential. This study compared the nutritional composition and antioxidant activity of quinoa sprouts from different varieties at various time points.
View Article and Find Full Text PDFLactic acid bacteria (LAB) are the most common probiotics, and they present excellent inhibitory effects on pathogenic bacteria. This study aimed to explore the anti-biofilm potential of the purified active substance of , named Z102-E. The effects of Z102-E on were investigated in detail, and a transcriptomic analysis was conducted to reveal the anti-biofilm mechanism.
View Article and Find Full Text PDFAnimals (Basel)
August 2024
Pig carcass traits are among the most economically significant characteristics and are crucial for genetic selection in breeding and enhancing the economic efficiency. Standardized and automated carcass phenotyping can greatly enhance the measurement efficiency and accuracy, thereby facilitating the selection and breeding of superior pig carcasses. In this study, we utilized phenotypic images and data from 3912 pigs to propose a deep learning-based approach for the automated determination of pig carcass phenotypic traits.
View Article and Find Full Text PDFThe prevalence and impact of Getah virus (GETV) are significant concerns in China. GETV can infect a wide range of animals, including horses, pigs, sheep, cattle, birds, and humans, resulting in substantial losses in the livestock and agricultural industries. GETV infection can cause the development of ulcers and inflammation in the mouth and gums of horses, which result in pain and discomfort and lead to symptoms such as reduced appetite, drooling, and difficulty chewing.
View Article and Find Full Text PDFWater contamination poses a significant challenge to environmental and public health, necessitating sustainable wastewater treatment solutions. Adsorption is one of the most widely used techniques for purifying water, as it effectively removes contaminants by transferring them from the liquid phase to a solid surface. Bio-based hydrogel adsorbents are gaining popularity in wastewater treatment due to their versatility in fabrication and modification methods, which include blending, grafting, and crosslinking.
View Article and Find Full Text PDFCD8 T cell activation leads to the rapid proliferation and differentiation of effector T cells (T), which mediate antitumor immunity. Although aerobic glycolysis is preferentially activated in CD8 T, the mechanisms that regulate CD8 T cell glucose uptake in the low-glucose and acidic tumor microenvironment (TME) remain poorly understood. Here, we report that the abundance of the glucose transporter GLUT10 is increased during CD8 T cell activation and antitumor immunity.
View Article and Find Full Text PDFObjective: Qiliqiangxin (QLQX) capsule- a traditional Chinese medicine used for treating heart failure (HF), can modulate inflammatory cytokines in rats with myocardial infarction. However, its immune-regulating effect on dilated cardiomyopathy (DCM) remains unknown. The aim of this study was to investigate whether QLQX has a unique regulatory role in the imbalance of pro- and anti-inflammatory cytokines in patients with DCM.
View Article and Find Full Text PDF