Serum urea concentration and risk of 16 site-specific cancers, overall cancer, and cancer mortality in individuals with metabolic syndrome: a cohort study.

Background: The relationship between serum urea concentration and cancer in patients with metabolic syndrome (MetS) remains unclear. This study aimed to investigate the association between serum urea concentration and 16 site-specific cancers, overall cancer incidence, and cancer mortality in individuals with MetS.

Methods: We analysed the data of 108,284 individuals with MetS obtained from the UK Biobank.

Effects of Psychological Intervention Based on the Self-Transcendence Theory on the Sleep Quality of Chinese Nurses.

Background: COVID-19 infection is transmitted easily and quickly, exposing medical care workers, especially nursing workers, to tremendous stress. Therefore, identifying the factors influencing the sleep quality of nurses and implementing corresponding interventions are conducive to improving the sleep quality of nurses and enhancing their nursing quality.

Methods: Form September to December 2022, a survey-based evaluation was conducted on 1074 front-line clinical nurses randomly selected from three hospitals in Zhejiang Province, China.

Association of tea and coffee consumption with the risk of all-cause and cause-specific mortality among individuals with metabolic syndrome: a prospective cohort study.

Background: The relationship between tea and coffee consumption and mortality among patients with metabolic syndrome (MetS) remains barely explored. Herein, this study aimed to examine the association between tea and coffee consumption and the likelihood of all-cause and cause-specific mortality in patients with MetS.

Methods: A total of 118,872 participants with MetS at baseline from the UK Biobank cohort were included.

Impact of the Interaction Model of Client Health Behavior on the Physical and Psychological Health of Patients with Limb Fracture.

Background: During rehabilitation, patients with limb fracture should receive physical and psychological nursing. The study aimed to explore the intervention effect of the Interaction Model of Client Health Behavior on the physical and psychological health of patients with limb fracture.

Methods: Convenience sampling was used to recruit patients with limb fracture who underwent orthopedic treatment in three hospitals in Zhejiang Province, China from 2021-2022.

Reliability and validity of the Chinese version of the spiritual health scale.

Background: In recent years, spiritual health became a focus of interest and nurses' spiritual health is crucial to the quality of their own lives and patients' health care. In China, high workloads, tense nurse-patient relationships, and low social status have been found to have negative impacts on the work attitude and nursing quality and spiritual health offers direction for solving this problem. This study assessed the spiritual health levels of nurses on the Chinese mainland using a revised Chinese version of the spiritual health scale (SHS-C).

Antifungal itraconazole ameliorates experimental autoimmune encephalomyelitis through a novel mechanism of action.

Background: Multiple sclerosis (MS) is an autoimmune disease characterized by a loss of myelin, limb disabilities and dysregulation of gene expression. Unfortunately, there still is no treatment to cure MS.

Objectives: To explore a novel way to treat MS using currently available antifungal drugs.