- The study investigates the effects of Dapagliflozin (DAPA), an SGLT2 inhibitor, on diabetic retinopathy (DR) in mice, highlighting its potential benefits for eye health in diabetes.
- Treatment with DAPA for 8 weeks showed metabolic improvements in mice, such as better glucose tolerance and reduced retinal damage, alongside increased levels of a beneficial growth factor, FGF21.
- Results suggest that inhibiting SGLT2 could be a promising new therapeutic approach for preventing retinal damage in diabetic patients, indicating the role of SGLT1 in this process as well.