Mechanisms of Linezolid Resistance in Mycobacteria.

Mycobacteria form some of the most notorious and difficult-to-treat bacterial pathogens. As a group, they are intrinsically resistant to many commonly used antibiotics, such as tetracyclines and beta-lactams. In addition to intrinsic resistances, acquired multidrug resistance has also been observed and documented in (MTB) and non-tuberculous mycobacteria (NTM).